February Mandate Roundup: 79 Investors from 13 Countries

By Lucy Parkinson, Senior Research Manager, LSN

lucy 10*10This February, LSN’s research staff in Boston has seen not only a lot of snowfall, but also a lot of mandates. We spoke with a total of 79 investors during this short, snowy month. As Figure 1 demonstrates, we had conversations with every type of life science investor that LSN tracks:

 

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Figure 1 | Source: LSN Investor Platform, Data as of February 28, 2015

These investors are also diverse geographically; although most are based in the U.S., we also spoke to investors in 12 other countries around the world (see Figure 2). Fourteen of these investors are based in Asia, a region often untapped by entrepreneurs located outside of it; LSN has discovered through our mandate interviews that most Asia-based life science investors are looking beyond the region for investment opportunities. 

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Figure 2 | Source: LSN Investor Platform, Data as of February 28, 2015

As you can see in Figure 3 below, almost half of these investors are interested in opportunities globally. The rest focus on one or several specific geographic regions, with the U.S. being the most common.

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Figure 3 | Source: LSN Investor Platform, Data as of February 28, 2015

The investors we contact have varied interests across the life sciences; some invest opportunistically in any part of the field, whereas others focus on a particular area of speciality. In February 2015, the diagnostics sector attracted interest from the greatest number of investors, followed by medical technology and biotech therapeutics (see Figure 4). We’ve found from our discussions with investors that diagnostics companies receive attention from both medtech investors interested in diagnostic devices and imaging technologies, and also from biotech investors interested in molecular diagnostics and personalized medicine. In addition to these three sectors, we also speak to investors who are interested in engineering companies (including companies developing lab equipment or healthcare IT products), biotech R&D companies (including CROs), and other biotech opportunities such as industrial biotech or agricultural biotech.

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Figure 4 | Source: LSN Investor Platform, Data as of February 28, 2015

LSN focuses on researching investors who are open to early stage life science opportunities, and those represented in February’s mandates are no exception. The investors we spoke with are most likely to be focused on companies that have successfully passed through the IDE/IND stage and have products in early clinical trials. However, we also spoke to many investors who look at other opportunities, including those offered by very early stage companies as well as late stage companies that have begun marketing their product. Figure 5 shows the stages at which diagnostic and medical technology investors prefer to invest:

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Figure 5 | Source: LSN Investor Platform, Data as of February 28, 2015

Figure 6 shows the stage at which biotech therapeutics investors prefer to invest. In this sector, you can see that interest in fully developed products drops off sharply, due to the much longer development cycle involved.

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Figure 6 | Source: LSN Investor Platform, Data as of February 28, 2015

While this roundup provides an overview of the information we have recently gathered regarding investor interest, we collect many other details that help us identify suitable opportunities for each investor, including which indication areas and technological approaches the investor focuses on, and what kind of financing rounds the investor is open to participating in. These details are invaluable to a life science company looking to find the right investor fit. We look forward to speaking with more life science investors during March and beyond.

Hot Life Science Investor Mandate 1: Corporate Venture Capital Firm Seeking Pre-Clinical Stage Novel Platform Therapeutics

A large European pharmaceutical company recently opened a US office to invest out of a $130 million evergreen corporate venture fund. The fund is interested in life science opportunities globally, and expects to make 3-4 new investments per year. The fund typically invests about $10 million over the life of an investment.  The fund is typically a lead investor, and participates in syndicates with other investment firms.

The fund seeks to invest in companies with preclinical assets.  The firm prefers to invest in companies developing therapeutic platform technologies.  The fund is only interested in novel technologies; while the fund will consider investing in any form of therapeutic technology, gene therapy and regenerative medicine are particularly of interest.  The fund is focused on investing in oncology, but will also consider opportunities in other indication areas.

The fund invests in technologies of strategic importance to its parent company. The fund only invests in privately held companies.  The fund typically does not invest in single asset opportunities; only companies with multiple pipeline assets are of interest.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Life Science Investor Mandate 2: Chinese PE Firm Looking Globally for Medical Device, Diagnostic and Healthcare IT Opportunities

A private equity firm that was founded in 2004 and is headquartered in China is currently seeking new opportunities. The firm provides venture capital and growth capital to early-stage companies across various industries, including life sciences, energy, Internet and software. The firm is interested in all types of life science companies except drug development. The allocation size will vary, but the firm has the capability to allocate up to $20 million per company, depending on the opportunity. The investment is typically in form of equity, but convertible loan will be considered as well. The firm has an emphasis on technologies and products, and it is currently seeking new investment opportunities globally.

The firm is currently seeking to invest in medical device, diagnostics, biotech R&D services and healthcare IT sectors. The firm is very opportunistic in terms of subsectors and indications. Currently the firm will not invest in companies targeting drug development.  The firm will consider companies at all stages of development, from pre-clinical stage all through to commercial stage; however, the firm is most interested in companies in the pre-commercial stage.

The firm primarily invests in early-stage private companies. The firm does not have specific requirements for companies’ management team or revenues. The firm will take a board seat post-investment.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Life Science Investor Mandate 3: Swedish VC Fund Seeking Clinical Stage Therapeutics Throughout Europe

A Swedish venture capital fund that invests in life science companies with a focus on therapeutics is currently seeking new opportunities. The firm has raised six funds to date, with the most recent fund size of €110M (2011 vintage). The firm can allocate up to €10-15M per company and typically provides equity as well as debt financing. The firm generally acts as the lead or co-lead investor and is open to invest in syndicates. Currently, the firm seeks to invest in companies that are based in the European Union or US company that is open to establish an EU entity.

The firm is currently seeking to invest in early to mid stage biotech therapeutics and pharmaceuticals. The firm is also interested in exceptional medical devices with a therapeutic application that is close to market or has generated some sales. The firm is opportunistic across the therapeutic subsectors but prefers products that target niche indications.  Currently, the firm is more interested in oncology and orphan indications.  The firm looks for products with proofs of concept in Phase I and II.

The firm requests a board seat in each portfolio company. The firm seeks a strong and experienced management team.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Life Science Investor Mandate 1: Corporate Venture Arm of Healthcare Consortium Seeking Device, Diagnostic and Healthcare IT Opportunities

The corporate venture capital arm of an integrated health care consortium based in the United States manages ~ $410 million in assets and is making the investments out of a ~$150 million dollar fund. The firm can invest as little as $5 million but tends to allocate $7-$10 million initially, and $10-$15 million over the lifetime of an investment. The firm only invests in preferred equity rounds, is comfortable leading life sciences deals, particularly in healthcare IT. The firm only invests in US-based and incorporated companies. The firm is involved in approximately 4-5 new investments each year.

The firm is currently looking for companies in healthcare IT, healthcare services, diagnostics, medical devices, and drug delivery. Companies that are able to benefit the firm’s existing healthcare members are of particular interest. The firm is indication agnostic, however, and is not interested in investing into companies working with novel compounds or therapeutics. The firm is looking for mid to later stage companies for investment.

The firm looks to invest in companies that have already received institutional funding from highly qualified investors where the investor syndicate has majority stake in the company. The firm will consider companies that are both pre and post revenue, but is primarily interested in companies with early (single digit millions) commercial traction. The firm started making investments out of its fourth fund earlier this year.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Life Science Investor Mandate 2: Taiwanese PE Firm Seeking Global Biopharmaceutical, Medtech, and Diagnostic Opportunities

A life science dedicated PE fund of a Taiwanese company engaged in leasing, finance, and investment businesses is currently seeking new opportunities. The fund prefers to invest in early stage companies but is also interested in growth-expansion stage companies. The fund can invest up to USD 30 million or more per company.  The fund will focus on companies founded and operated in the Greater China region (60% of fund allocation). The fund is also interested in opportunities from Europe (especially in Switzerland, Germany, and the UK) as well as from the US.

The fund seeks to invest in biopharmaceuticals and medical technologies. In biopharma, the fund focuses on novel drugs, drugs with new indication/dosage form, biosimilar, and API for cancer drug. The fund looks for proprietary drug discovery or development technologies that are able to build a multi-product pipeline and products that address large unmet medical needs. For medical technologies, the firm focuses on molecular IVD test/next-generation sequencing, monitor & diagnostics system, invasive devices, cosmetics/plastic surgery, ICT medical device, and combination products with Greater China market potential. The firm looks for new and innovative technologies that can increase performance, lower cost or open up new business models.

The fund prefers to invest in early stage companies and generally acquires a minority stake in the company. However, the fund does not rule out the possibilities of acquiring a controlling stake if the strategic value exists.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Life Science Investor Mandate 3: Southwest Based VC Seeking Pre-clinical Stage Life Science Opportunities throughout US

A venture capital firm based in the southwestern United States manages 2 funds for a combined total of $270 million in assets under management. The firm generally invests between $2-$6 million of equity capital per round and up to $10-$15 million over the life of the investment. The firm plans to invest in 2-5 companies over the next 6-9 months and will consider firms located throughout the United States.

The firm is currently looking for companies developing Medical Devices, Therapeutics, Diagnostics and Healthcare IT products. For medical devices and therapeutics the firm is open to the full spectrum of subsector and indication and will consider companies developing orphan indications. The firm is interested in seed and venture stage companies, generally looking to invest in companies with a lead asset in pre-clinical trials. Only in certain cases of reformulation and repurposing would the firm consider investment into a company with a product in clinical trials. The firm is also willing to consider companies targeting orphan indications. In the Healthcare IT space the firm has stated interest in areas of clinical sequencing and diagnostic platforms but will also consider other companies that fall into the Healthcare IT space as well with the exception of traditional EMR companies. The firm is also considering investment into mobile health companies developing consumer facing apps.

As such an early stage investor, the firm invests almost exclusively in pre-revenue companies. The firm also looks for experienced management teams and generally takes a seat on the company’s board.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com