Hot Investor Mandate: USA-Based VC Firm Seeks Longevity-Focused Investments, Engaging in Seed to Series A Rounds

A venture capital firm based in the US is focused on incubating and investing in longevity-focused companies that aim to improve quality of life for older adults. The firm primarily invests at the Seed and Series A stages, with typical initial check sizes ranging from $100,000 to $500,000. The investment focus is on opportunities based in the United States. 

The firm invests broadly across the life sciences and healthcare sectors, provided there is a clear connection to aging and longevity. Areas of interest include healthcare quality and cost, care capacity, healthcare benefits activation, aging in place, and financial longevity. The firm has made investments in medical devices, diagnostics, and digital health companies, and currently maintains an active portfolio of more than 15 companies. It generally does not invest in biotech. The firm is open to backing companies at the earliest stages of development. 

There are no specific requirements regarding company structure or founding team experience. The firm is flexible in its role and may choose to lead or co-invest depending on the opportunity. 

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com. 

Hot Investor Mandate: Late-Stage Venture & Growth Equity Investor Backing De-Risked Therapeutics and Medical Device Opportunities

A venture capital and private equity firm focuses on investments in the life sciences sector, with a primary emphasis on pharmaceuticals and therapeutics, and a secondary interest in medical devices. The firm invests from Series A through growth-stage transactions and is currently deploying capital from its third fund. Typical investment sizes range from $10 million to $40 million. 

The firm prioritizes opportunities with a de-risked clinical development pathway, such as those involving repurposed or reformulated drugs, established mechanisms of action, 505(b)(2) regulatory strategies, or programs with proof-of-concept clinical data. For therapeutic assets, the firm primarily targets clinical-stage companies, ideally with completed Phase I trials. For medical devices, the firm considers clinical-stage opportunities with a clear regulatory and commercialization path. The firm is indication-agnostic but maintains a strong interest in 505(b)(2) products.  
 
The firm seeks companies with a clearly defined path to regulatory approval, supported by robust intellectual property and market exclusivity. It plays an active role in its portfolio companies and takes a board seat in every investment. 

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com. 

From Lab to Market: Why Life Science Companies Are Drawn to Singapore 

By Claire Jeong, Chief Conference Officer, Vice President of Investor Research, Asia BD, LSN

LSN is proud to announce our partnership with Enterprise SG for RESI JPM 2026, to foster meaningful conversations on global life science innovation, investment and cross-border collaboration. Learn how Singapore is a dynamic launchpad for innovation and home to cutting-edge startups ready to collaborate on your next breakthrough. Join us at our upcoming panel on January 12 to find out more! 

As global healthcare challenges intensify, innovative biomedical technologies from Asia are stepping up to drive change, translating life science research into real-world solutions. Increasingly, investors, corporates, startups, and healthcare systems around the world are seeing the urgency in bridging the East and West to improve healthcare outcomes and deliver value-based care.

Singapore, located at the heart of Asia, is a dynamic hub for biomedical innovation, driven by a strong network of global investors, researchers, mentors, and innovators. With decades of sustained government investments and a robust talent pipeline from world-class universities and research institutes, it is home to over 500 biomedical and medtech companies. The ecosystem has attracted venture capitalists and venture builders like MPM BioImpact, Polaris Partners, and Flagship Pioneering, as well as global pharma leaders such as Pfizer, Roche, and Johnson & Johnson. These players work closely with government agencies, like Enterprise Singapore, that drive startup development, provide patient funding, expertise, infrastructure, and networks crucial for producing globally competitive solutions.

Singapore’s strategic position as a bridge between Asian and global markets enables it to play an outsized role in driving biomedical advancements. This works both ways, as a gateway for global companies to access the growing opportunities in Asia, and as a springboard for regional companies to expand worldwide. For example, through partnerships with healthcare organisations like Cedars-Sinai and Mayo Clinic in the US, Enterprise Singapore supports Singapore startups to test and scale their solutions in overseas markets, facilitating a bi-directional flow of innovation to improve healthcare for communities.

Join Enterprise Singapore at the ‘Asia Cross Border Investments Panel’ to explore how cross-border capital, talent, and technologies are converging to drive breakthroughs in precision medicine, innovative therapies, and next-generation diagnostics. The panel will take place on January 12, 2026, from 11:00 am to 12:00 pm at RESI JPM by LSN, held at the Marriott Marquis, San Francisco. Learn from prominent industry leaders how transcontinental partnerships, including those with Singapore, are shaping the future of healthcare innovation – from discovery to global commercialisation.

To join the conversation, please contact Claire Jeong, VP of Investor Research, Asia BD, at c.jeong@lifesciencenation.com.

Hot Investor Mandate: Early-Stage Focused VC Firm Invests in Pre-Seed to Series A Healthcare Companies With AI-Driven Technologies

This venture capital firm with offices in the US is exclusively focused on the AI transformation of healthcare, operating through a physician-centric model that leverages a broad network of medical professionals actively involved in both the investment process and the development of AI solutions, particularly in medical imaging. 

The firm invests at the pre-Seed, Seed, and Series A stages, with typical check sizes ranging from $1 million to $2 million. While most investments have been made in U.S.-based companies, the firm remains open to international opportunities, including those in Europe and Asia. 

Investment focus is tightly concentrated on disruptive AI-driven technologies in the medical imaging market. The firm does not invest in traditional therapeutics or medical devices, and is currently not considering opportunities outside of AI-centric digital health technologies related to imaging. It is open to investing in companies as early as the pre-prototype stage, provided they are aligned with the firm’s strategic thesis. 

The firm seeks to partner with highly driven management teams who possess deep domain expertise across imaging, artificial intelligence, and medical software. While the firm typically co-invests, it maintains an active, hands-on approach, especially through the support of its physician investor network, which helps accelerate product development and clinical relevance. 

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com. 

Hot Investor Mandate: Family Office-Backed Life Sciences Fund Invests Across Therapeutics, Diagnostics, and Digital Health Globally

This life sciences-focused investment firm backed by a prominent family office is actively investing in life science and healthcare companies across the globe, with a focus on those that are based near their headquarters. 

The firm invests in early-stage healthcare companies, with interest in therapeutics, diagnostics, and digital health. It is agnostic to technology type and therapeutic indication, but prefers opportunities with robust pre-clinical data. The firm is open to both pre-clinical and clinical-stage projects, though it does not invest in medical device companies at this time. 

The firm is focused on supporting innovative technologies and is open to partnering with both first-time and experienced founding teams. It is flexible in its role, willing to act as either a lead investor or a co-investor, depending on the structure and needs of the financing round.

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com. 

Hot Investor Mandate: Evergreen Fund Actively Seeking Therapeutics and Medical Device Opportunities, Investing Up to $10M in the US and Beyond

This corporate strategic evergreen fund based in the US has invested in over 50 life sciences companies and considers both public and private opportunities in the United States and internationally. The firm is a flexible investor, with initial allocations typically ranging from $1 million to $10 million, depending on the developmental stage of the company. 

The firm invests in therapeutics and medical devices, with the latter limited to implantable products requiring PMA submission. It invests exclusively in companies with clinical-stage assets, and is indication-agnostic, open to innovation across all areas of medicine. 

This investor adopts a flexible approach to management teams, and is willing to take a more hands-on role in cases where founding teams have limited internal resources. A high level of transparency is required from portfolio companies, and the firm actively supports strategic planning around value-driving clinical studies that can meaningfully advance the company’s trajectory. 

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com. 

Hot Investor Mandate: Europe-Based VC Invests Across All Life Science Sectors, With A Focus on Those Based in US and Europe

A Europe-based venture capital firm invests across two primary verticals: healthcare innovation and sustainability. The firm typically invests at the seed stage, with initial check sizes ranging from €1 million to €5 million. Its geographic deployment is relatively balanced, with approximately half of investments made in Europe and the other half in the United States. The firm shows particular interest in U.S.-based companies founded by European entrepreneurs. 

The firm invests across therapeutics, diagnostics, medical devices, and digital health, taking an agnostic approach within these sectors. It does not enforce strict criteria regarding the composition or background of founding teams. 

Open to both leading and co-investing, the firm places strong emphasis on the mission and purpose behind each company, placing value on teams with a compelling “why” that drives their approach to solving pressing problems in healthcare. 

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com.