Highlights of 2015: Next Phase’s Top 10 Articles

By Lucy Parkinson, Director of Research, LSN

Nono Hu, Director of Marketing, LSN

We’ve covered many topics in life science fundraising over the last year, and here’s a roundup of the articles that won the most reader appeal. The list includes some retrospectives and look-aheads, some deep dives on working with a pharma company or with a philanthropic fund, and some tactical tips on how to meet an investor and build a productive relationship. We hope you’ll enjoy taking a second look at these 2015 highlights.

Year-End Roundup: Pharma Licensing Deals

By Lucy Parkinson, Senior Research Manager, LSN

In recent years, big pharmaceutical companies have filled their pipelines by turning to smaller partners to find innovative products, and 2014 has been no exception. This year has produced so much dealmaking news that you may have lost track of all the new partnerships. But we’ve dug into the LSN Licensing Deals Platform to examine the key data points from the year’s pharmaceutical licensing activity.

READ MORE

11 Tips for Creating a Successful Pitch Deck

By Shaoyu Chang, Research Analyst, LSN

Coming from a scientific background, I thought I knew well enough about using slides and making presentations, whether in laboratory journal clubs or at hundred-attendee conferences. However, as I start to help fellow scientists on their fundraising campaigns, it has become apparent to me that academia and business speak very different languages.

READ MORE

Formulating the Introductory Email to Potential Investors

By Michael Quigley, Research Manager, LSN

Having personally scheduled and held several hundred interviews with Life Science investors over the past year, I have developed and refined a formula for getting “in the door” with an introductory email. As anyone who has embarked on a fundraising campaign knows, initiating the dialogue is often the hardest part of the process. Few introductory emails ever get opened, and even fewer earn a reply at all. However, there are a few concepts and tactics that can increase your efficacy substantially when it comes to initiating a dialogue and locking in that first meeting. This article will share some insights from my personal experience that may be helpful in your email outreach.

READ MORE

CRO Trends in 2015

By Alejandro Zamorano, VP of Business Development, LSN

LSN maintains regular dialogue with a broad spectrum of contract research organizations (CROs) – from top-tier full service organizations, to small niche-specialized research companies; some are customers of the LSN Company Platform, and others are friends. Every year we talk to hundreds of business executives in the field. Based on our market insight, here are the top trends we see in 2015.

READ MORE

How to Write a Compelling Partnering Message

By Alejandro Zamorano, VP of Business Development, LSN

Life Science Nation attends many partnering conferences, in addition to hosting our own quarterly Redefining Early Stage Investments (RESI) Conference series. After taking the time to study the most successful partnering requests and interviewing investors about what they look for in an introductory note, we have created a template email, which should increase your response rate when soliciting investment:

READ MORE

The Life Science Venture Philanthropy Landscape

By Michael Quigley, Director of Research, LSN

LSN researchers recently decided to take a deep dive into interviews we have held with venture philanthropy groups from around the world to see what the future likely has in store. After analyzing data gathered over the past three years from more than 150 investors, we uncovered a few notable trends.

READ MORE

Getting the Most from a 30-Minute Investor Meeting

By Michael Quigley, Director of Research, LSN

As a fundraising entrepreneur, you will likely find yourself engaging in initial face-to-face meetings with investors, whether at a conference, coffee shop, or in an office. Given the time constraints inherent in these kinds of meetings, it is crucial that you have a plan in place in order to get as much as possible out of them. What follows are suggestions for how best to manage one of these conversations.

READ MORE

How Do Investors Assess a Management Team?

By Lucy Parkinson, Senior Research Manager, LSN

LSN Research often hears from investors that when choosing a company to invest in, a sound management team is just as important a factor as the quality of that company’s technology. Developing an innovative biotech or medtech product is a lengthy process fraught with risks, and it takes a strong management team to successfully guide a scientific discovery through all the challenging steps. So what are the qualities of the ideal management team, and how will investors judge whether yours has what it takes? Investors have reported the following important attributes:

READ MORE

Family Offices: The New VCs

By Dennis Ford, CEO, Life Science Nation

There is not enough capital to fund all of the good ideas from life science companies, which is a major challenge for life science CEOs today. To identify the next not-so-obvious investors, fundraising executives should look to the capital-raising practices of start-ups in other industries. If they do, they will learn that the basic premises include thinking outside the box and being flexible and more creative.

READ MORE

Pitching to a Foundation? Be Prepared for These Issues

By Lucy Parkinson, Director of Research, LSN

Earlier this year, we offered an in-depth exploration of foundations that provide funding to startup companies. Many foundations and patient groups are now interested in working with startup companies to fund projects that further their mission, and while many life science companies could benefit from approaching foundations for funding, there are certain criteria that foundations typically have to follow in order to bring their support for startup companies in line with their broader mission.

READ MORE

Redefining Early Stage Investments (RESI) Conference: Biotech Family Office Panel

By Cole Bunn, Research Analyst, LSN

cole-wp

Family offices are an investor class that has recently garnered a lot of attention from life science entrepreneurs. Their wide variety of motivations and transaction types and generally speaking, more flexible term sheets, make these investors a great partner for biotech companies undertaking the daunting task of commercializing therapeutic products.

At RESI San Francisco, the Biotech Family Office Panel will provide insights into each represented firm’s current interests and outlook on the biotech sector, how they source and evaluate deals and their position in the investment ecosystem.

Moderated by Lisa Rhoads, Managing Director, Easton Capital, this panel will feature:

If you’re interested in listening to this panel live at RESI, you can register for RESI San Francisco now. RESI provides a great opportunity to expand your network in the life sciences and to get a better understanding of fundraising process, and January 12th will be our largest gathering yet.

RESI-San-Francisco-2016

Happy Holidays from Life Science Nation

By Dennis Ford, Founder & CEO, LSN

dennis-websit

As we head home to our families today, Life Science Nation would like to wish you all a very happy holiday. We’re looking forward to a new year full of further growth in the life science sector, and new connections and dialogues between all sides of the health technology marketplace. Next Phase will return next week with more insights into the year’s fundraising trends; until then, keep warm, and have good cheer.

xmaslsn1

RESI Panel Announcement: Early Stage Therapeutics

By Nicholas Civitarese, Research Analyst, LSN

nick-wp

Early stage therapeutics companies have a long road ahead to reach the marketplace, and will require significant investment along their way. The search for development capital is therefore a constant challenge for therapeutics startups.

Life Science Nation is pleased to announce a panel of 5 people with extensive experience in early stage therapeutics for RESI San Francisco on January 12th. Moderated by Dennis Purcell, Founder and Senior Advisor at Aisling Capital, the panel will feature:

This panel will give fundraising entrepreneurs a firsthand look at the strategies used by early stage therapeutic investors to assess companies at the earliest, riskiest stage of development, and will help the audience to position their companies as an attractive investment opportunity.

By registering for RESI San Francisco, you’ll be able to listen to the early stage therapeutic panel live in person. January 12th will be our largest conference yet and provides fundraising entrepreneurs with numerous opportunities to expand their network in the life sciences and to learn more about the fundraising process.

RESI-San-Francisco-2016

Crowdfunding & Reg A+ Workshop: Hear From the Experts

By Laura Chess, Business Development, LSN

laura-10-10The SEC has just released the long awaited crowdfunding regulations on the heels of Regulation A+ that went effective in June. Together they create two new exciting pathways to raise capital for your growing life science company.

This workshop will take place at RESI San Francisco at 11am on January 12th. Whether you are raising $1 million or up to $50 million, hear from experts who can guide you through the process with practical advice to see if these new alternatives are right for you. You’ll learn how to “Test the Waters” to assess potential investor interest, learn how to prepare the streamlined Form 1-A and how to create a market for your shares.

This RESI workshop will be presented by four experts in the field:

RESI-San-Francisco-2016

Redefining Early Stage Investments (RESI) Conference: Healthcare IT Investors Panel

By Shaoyu Chang, MD, MPH,  Senior Research Manager, LSN

Shaoyu 10*10

At the intersection between life science and computer science, healthcare IT continues to attract strong interests from both camps. VC funds, big pharmas, and tech corporates are all actively seeking the next big thing in HCIT that would transform healthcare fundamentally.

Some of the biggest players in HCIT investment will speak at RESI San Francisco to share their expertise and advice with entrepreneurs. Moderated by Anne DeGheest, Founder of HealthTech Capital, the panel will feature:

This panel will provide fundraising entrepreneurs with an inside peak into the strategy of these HCIT investors – How do you make your company stand out in this crowded marketplace? What do investors see as the most high-potential fields of innovation in healthcare IT? How do you demonstrate to an investor that your product has the potential to succeed?

If you’re interested in listening to this panel live at RESI, you can register for RESI San Francisco now. RESI provides a great opportunity to expand your network in the life sciences and to get a better understanding of fundraising process, and January 12th will be our largest gathering yet.

RESI-San-Francisco-2016

How the Affordable Care Act Affects Investor Mandates

By Lucy Parkinson, Director of Research, LSN

The Affordable Care Act (ACA), passed in 2010, has had a profound impact on the US healthcare industry; its provisions have been implemented gradually, and investors in the life science sector have been paying close attention to its impact in their search for new opportunities. The ACA has been particularly impactful in healthcare IT investment, and we have also seen some effects in medical technology. As LSN’s research staff continue to converse with investors, several have spoken about this trend in depth. Here are a few effects of the ACA that our investor dialogues have brought to light.

Investors Find Opportunities in ACA Incentives

The ACA provides financial incentives and penalties for care providers to meet certain care quality goals. Some investors are therefore seeking technologies that will help care providers achieve these ACA-defined goals, as these technologies have the potential to be rapidly adopted by care providers seeking to meet ACA targets and avoid penalties.

For example, since 2012 hospitals have been penalized by a reduction in Medicare payments if they have high readmission rates. Some investors are therefore focused on services that can prevent readmission, such as data-driven care management platforms that will identify patients that need more support after being discharged from hospitals and connect those patients with services outside the hospital setting. Hospital safety is another area in which the ACA has created incentives, and some investors are focused on technologies that improve surgical safety or address hospital-acquired infections.

Investor Relationships with Hospitals Matter

As the aforementioned ACA incentives focus significantly on hospitals, investors with an eye to the ACA are typically seeking to invest in products that will be used in a hospital setting, or which focus on hospitals as their customer market. Several investors have focused on building relationships with hospitals or hospital networks; the investors can tap these relationships to help them assess deals, or to drive adoption of a product in which they’ve invested. Hospital consolidation is a significant trend within healthcare, and this consolidation often leads to hospitals becoming more powerful as customers, with the potential to drive rapid adoption of a product if it offers them better value than the status quo. In addition to building their own relationships with hospitals, investors will also consider whether a company is well positioned for working with hospital networks as customers and what existing relationships the companies have formed with major hospitals.

Insurance Companies Making Venture Investments

The health insurance industry is rapidly changing and consolidating in the new environment. An ACA feature called the Medical Loss Ratio compels insurers to spend 80-85% of premiums on providing care or improving the quality of care; as investing in new technologies can be classed as quality improvement spending, several insurance companies are now getting hands-on about investing in new healthcare technologies that can be deployed throughout their networks. Some insurers have become LPs in venture capital funds, whereas others have launched their own corporate VC arms. Consistently, LSN has found that these entities are primarily focused on healthcare IT and healthcare service opportunities that align with the ACA incentives; in many cases, the insurer may become investor and customer, and can use their internal resources to assess the value of a new product or service.

If your company’s technology aligns with one of the incentives outlined in the ACA, it’s definitely an angle that’s worth emphasizing in your pitch to investors, as many have a specific interest in investing in helping care providers meet their ACA goals. ACA implementation is changing many aspects of the healthcare industry, and a savvy CEO will position their company favorably in the new landscape.