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Closing the Funding Gap in Europe 

18 Apr

By Greg Mannix, Vice President International Business Development, General Manager Europe, LSN

We have all heard that 2023 was a difficult year for early-stage funding. One theory is that pharma M&A activity lagged and reduced the incentive for investment into new life sciences funds, combined with the general expectation that a global recession was coming, leading VCs to invest mainly in their current portfolio companies and not so much into new ventures.

Thankfully, the recession didn’t materialize, and some pharma execs point to favorable conditions that connote an uptick in M&A activity that will bring a kind of trickle-down effect and benefit the early-stage folks. The impressions I have gathered at this year’s first two RESI conferences have been upbeat about the months ahead.

In Europe, I have always been impressed by the government-backed grant and other funding programs available in each country to help the earliest startups get off the ground. These programs are augmented by excellent EU initiatives like Horizon and EIT. But what happens when European biotech and MedTech startups need to raise larger amounts to move their technologies along on the road to commercialization?

That’s where companies hit a wall; there isn’t enough venture capital on the old continent to fund all the fantastic technologies being developed. A European investor recently told me about one of his very successful portfolio companies that was at a stage where they needed to raise a significant round. Having difficulty finding sufficient co-investors in Europe, they eventually brought in a US investor to complete the round. This was only possible thanks to the European and US investors already having a relationship.

At LSN it has long been our goal to facilitate cross-border relationships, not only between companies and investors, but also between investors from different regions or countries. RESI Europe – Barcelona on June 17-19, 2024 is shaping up to be an especially international gathering. Hope to see you there!

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Hot Investor Mandate: VC Firm Invests in and Builds Companies in Healthtech and Tech-Enabled Health Services, Seeking Technologies in USA & Canada

18 Apr

A USA-based VC firm builds and invests in companies in the healthcare sector, with a focus on personalized health and consumer health.  The firm typically invests in seed or Series A rounds and initial investments range from  $150,000-$1.5 million, with a potential commitment of up to $5 million over the life of the investment.  The firm invests in the USA and Canada. 
 
The firm focuses on healthtech and tech-enabled health services. The firm is interested in disease management (includes chronic, autoimmune, mental/behavioral, neurology, microbiome, and digital therapeutics), care management, precision medicine, remote monitoring (including pushing the point of care into ambulatory settings such as retail clinics and the home), population health management (including underserved patients and Medicaid recipients, and patients living in areas outside the East Coast and West Coast).  The firm is also open to investing in devices and diagnostics, but only if they are targeted at consumers/patients as users, rather than physicians. 
 
The firm generally does not invest in companies that face FDA regulatory risk; the firm invests in companies with products that are already approved or do not require FDA approval. The firm prefers to invest in revenue generating companies but will consider startups that will begin to generate revenue in 6-12 months.

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com.   

Hot Investor Mandate: Global Investment Firm Seeks Novel Medical Device Opportunities, With Strong Interest in PMA Devices Across All Subsectors & Indications

18 Apr

Founded in 2019, a global venture capital firm specializes in investing in early-stage medical device companies. The firm is an active investor and can leverage their expertise and industry resources to provide support in many aspects. The firm prefers taking a leading role in investment rounds and may seek board seats in such cases. 
 
The firm focuses on medical devices and is open to looking at all subsectors and indications. The firm seeks innovative technologies, primarily investing in Class III devices and occasionally considering Class II devices if they demonstrate innovation. The firm is open to working with companies of all stages, including those in the early, “idea phase”. 
 
The firm prefers founding teams that have solid scientific expertise in their respective field and comprehensive knowledge of the space. 

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com.   

Announcing RESI Europe Panel Lineup 

11 Apr

By Joey Wong, Senior Investor Research Analyst, Hong Kong BD, LSN

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As a global conference series, RESI has organized events in North America, Europe, and Asia. This year, LSN (Life Science Nation) is bringing back our first RESI Europe since Covid, taking place in Barcelona, Spain on June 17th, 2024, and we are excited about expanding RESI’s global footprint and fostering connections and deal-making in Europe. For this highly anticipated conference, LSN has carefully curated a program of 10 investor panels covering a wide range of pertinent topics for early-stage investments and fundraising in life sciences and healthcare.

The panels at RESI Europe aim to bring forward a diverse group of investors and strategic partners, providing a comprehensive representation of the current investor landscape. This includes big pharma and corporate VCs, players capable of working with companies of all stages with various deal structures. The panels will also highlight groups that focused on providing early-stage funding, such as angels & family offices, and seed funds. Additionally, panels at RESI Europe will delve into different sectors or target areas, from the traditional “4 Ds” – drug/therapeutics, medical devices, diagnostics, and digital health – to innovative hot areas such as oncology innovation. Additionally, a panel will discuss cross-border investments, and how investors partner internationally. Please see the panel agenda below:

RESI Europe 2024 Investor Panels
Times
(All in CET)
Track 1
(Investor Panels)
Track 2
(Investor Panels & Workshops)
9:00
Seed Funds
Investing in the Earliest Stage Technologies
Big Pharma
Strategies for Pre-Clinical & Early Clinical Assets
10:00
Digital Health
Novel Approaches to Improve Quality of Care
Oncology Innovation
The Search for New Approaches to Diagnosing & Treating Cancer
11:00
Medical Devices
Forward Looking Trends in Medical Device Innovations
Early-Stage Therapeutics
Bringing the Newest Therapies to the Clinic
13:00
Angels & Family Offices
How Do Family Offices & Angels View Early-Stage Rounds?
Workshops
14:00
Diagnostics
Advancements for Personalized Care and Medicine
15:00
Cross Border Investments
Fostering Partnerships with Global Partners
16:00
Corporate VC
Firms Investing Beyond Financial Return

Whether you are an entrepreneur seeking funding or an active investor, these panels offer a full day of exceptional learning experiences along with your scheduled partnering meetings. Through organizing these investor panels, our goal is to provide entrepreneurs with valuable insights into early-stage fundraising and bridge the gap between entrepreneurs and investors, facilitating more efficient deal-making processes. For active investors in early-stage life sciences and healthcare, this also presents an unparalleled opportunity to share your investment strategies and highlight your firm/fund to a global audience. If you are interested in speaking at RESI Europe, please contact us.

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Liquet Medical has First-Time RESI Success!

11 Apr

Interview with John Schindler, CEO at Liquet Medical and John Newby, CEO at Virginiabio By Caitlin Dolegowski, Marketing Manager, LSN

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John Schindler
John-Newby
John Newby
Caiti
Caitlin Dolegowski

Caitlin Dolegowski (CD): Please introduce us to Liquet Medical and the company’s technology. How did Liquet Medical come to be?

John Schindler (JS): Liquet Medical is a development stage medical device company. Our first product to market is the Versus™ Catheter – a localized drug delivery catheter to treat blood clots in the lungs, a condition known as Pulmonary Embolism, or PE. This device has the ability to track the patient through real-time biometric data monitoring, allowing the physician to optimize the delivery of medication and the duration of the therapy. It will speed up time-to-treatment, lower hospital costs, and has the potential to reduce procedural complications and readmission rates.

The genesis of our company is rooted in a long-term business relationship with the inventor of the Versus Catheter, Dr. Patrick Kelly. Dr. Kelly is a serial inventor and practicing Vascular surgeon in Sioux Falls, SD who has routinely treated patients suffering from PE and decided there was a better way. I have worked closely with Dr. Kelly on several projects over the course of a 30+ year career in the medical device industry. This one being very personal to me in that my own mother passed from a Pulmonary Embolism shortly after the birth of my sister. As you can imagine, this has had a profound impact on my career and is what drives my passion to bring this particular innovation to the market.

CD: John, please introduce us to Virginia Bio. Virgnia had four companies participate in the Innovator’s Pitch Challenge at RESI South, what technology in the life sciences are you excited about coming from Virginia?

John Newby (JN): Virginia Bio is our Commonwealth’s life sciences trade group, representing and supporting a diverse group of med tech, diagnostic, pharmaceutical, digital health and other companies. We partner with regional and national coalitions to bring capital and impactful partnerships to our biotechs to grow Virginia’s $8.4 billion life sciences industry. In addition to exciting technologies like Liquet’s medical device, we are also particularly excited about our growing advanced pharmaceutical manufacturing capability that is a national leader in the onshoring of essential medicine production.

CD: John Schindler, this was your first RESI conference. I’d like to ask both of you about your experience at RESI? What was effective for you at RESI South?

JS: What I enjoyed most was how intimate this meeting felt despite the large number of attendees. The poster session gave attending companies a great opportunity for investors, fellow entrepreneurs, and ecosystem partners to understand and spend time together in an easy informal way. The pitch sessions were also a nice opportunity to share our innovation and coupled with a QA session led by panelists to help guide the conversation, provided opportunities for us to expand the audience understanding of the innovation. Also, providing opportunities for us to engage with investors in the partnering platform and also over breakfast, lunch and during the evening reception was outstanding. I managed to connect with many of the investors I was interested in meeting, and we’ve been able to follow up with them since. And lastly, I took a lot of notes listening to the curated panels and found the Seed Fund and VC panels particularly interesting. You all did a great job of attracting a lot of high-quality panelists for us to learn from.

JN: This was the first time that a coalition of seven southeastern states partnered to bring this well known investor conference to our region. RESI South brought over 200 investors into contact with a nearly equal number of life sciences companies, allowing scores of new connections and (ultimately, we hope) investments. The pitch competition that John competed in allowed our Virginia companies to both showcase their technologies and gain broader view into the work being done across our region. Our coalition’s goal in bringing RESI to Atlanta was to showcase all of our companies and increase investor visibility of our region. To this end, RESI South was more than effective.

CD: John Schinder, what stage of fundraising is Liquet Medical in and what milestone are you working toward currently?

JS: We are in the midst of closing our Seed round prior to a Series A offering early next year. And the major milestones ahead of us are our submission for our FDA 510(k) in the next few months and our expected FDA clearance later this year. We have an open convertible note and if any of your readers are investors interested in joining this round, let’s find some time to connect and discuss.

CD: Congratulations on your third-place finish at RESI JPM’s Innovator’s Pitch Challenge (IPC)! What do you think was the key to your success and standing out at RESI JPM?

JS: Thank you! It was great fun to share our innovation. I think the big key to our pitch success was having the opportunity to spend time with the meeting attendees around our poster before the pitch presentation. It made it easy to get them excited about what we are working on. I would encourage future companies to invest in the quality of their content. It’s a great tool and opportunity and I think what made the RESI meeting so interactive and successful for us. So, I’d give the credit to RESI for providing the additional visibility that ultimately contributed to our success.

CD: Another question for both of you. What advice would you like to give to entrepreneurs about RESI conferences?

JS: My advice would be not to fret about the 4-min time allotment for your pitch presentation – it’s plenty of time to share your innovation and ample available time in the QA to clarify your story further. Also, there is plenty of time to meet investors during the poster sessions, over lunch, and during the reception.

JN: An entrepreneur’s time an energy is very limited, and not every investor conference is likely to yield the results sought in terms of investor contact. RESI South was a unique opportunity for our entrepreneurs to attend an event that aimed for and achieved a nearly 1:1 ratio of investors to companies, and offered numerous opportunities to either pitch or present their technologies to those same investors. We understand that RESI conferences, generally have the same aims as RESI South in terms of opportunities for happy “collisions” with investors. Accordingly, for entrepreneurs looking to maximize their available time, RESI conferences may be a great choice.


If you’re interested in the next upcoming Innovator’s Pitch Challenge, you can apply for the RESI Europe 2024 IPC taking place June 17-19 with a 1-day in-person conference follow by 2-day virtual partnering at Hilton Diagonal Mar Barcelona in Barcelona, Catalonia, Spain. Applications are accepted on a rolling basis, so get your application submitted today!

RESI Europe registration opens at super early bird rates. Register now to save $500 by Tomorrow, Friday, April 12.

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Tech Hubs at RESI Europe

11 Apr

By Erika Wu, Business Development Manager, Global Tech Hubs, LSN

For the first time, Life Science Nation, Biocat are working together to host a RESI conference in Barcelona, Spain at the Hilton Diagonal Mar Barcelona Hotel.

RESI Europe will be a hybrid conference: June 17th will be in-person, followed by two days of virtual 1-1 partnering on June 18-19th. Attendees will represent early-stage life science startups, tech hubs, service providers, investors and strategic partners.

Global tech hubs ranging from bioclusters, incubators, accelerators, universities, non-profits, and government agencies are welcome to attend alongside their early-stage life science startups. Tech hubs and their startups are eligible for up to €500 off ticket options. To redeem a discount code or discuss your eligibility, please reach out to Erika Wu at e.wu@lifesciencenation.com

If your startups are not in fundraising mode, they can attend RESI Europe with an “Audience Access Pass” for €495, which gets access to view all in-person sessions (June 17th) including IPC pitch sessions, investor-led panels, workshops, exhibition, and a post-RESI networking reception.

Tech hubs that are interested in hosting an exhibition table and logo features will be eligible for a discounted rate to the “exhibitor level”, €3000 –> €2190 at RESI Europe. View sponsorship brochure.

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Congratulations to the RESI South Innovator’s Pitch Challenge Winners! 

4 Apr

By Claire Jeong, Chief Conference Officer, Vice President of Investor Research, Asia BD, LSN

At the inaugural RESI South, we had 43 companies participate in the Innovator’s Pitch Challenge (IPC). These finalist companies pitched to an audience and fielded questions from a panel of investor judges and exhibited a poster showing their technology at the conference. Many of the pitch companies were representative of the seven southern states that were selected by the SE Life Science Investor Coalition and the entities that make up the investor group; Bio Alabama, Bio Florida, Georgia Bio, Life Science Tennessee, NC Life Sciences Organization, SC Bio and Virginia Bio.

Registered RESI attendees (startup executives, early-stage investors, and industry experts), ‘invest’ or vote for their favorite IPC company with RESI cash provided, based on the pitch company’s poster board displayed at RESI’s exhibit hall and their performance in their pitch session.

Life Science Nation is pleased to share the winners who received the most votes during the RESI South. Congratulations to the winners!

1st Place – SiNON Nano Sciences

At SiNON Nano Sciences we specialize in a patented Carbon Nano Particle (CNP) drug delivery system, specifically designed for targeted treatment of Central Nervous System (CNS) diseases. Our unique release mechanism sets us apart in the market. Our tunable platform delivery system can encapsulate multiple therapeutics, including biologics weighing up to 500kD, and efficiently deliver them across the blood-brain barrier (BBB) to treat various neurological diseases. One of the key advantages of our CNPs is that they only open at the site of the disease, enabling higher concentrated doses while significantly reducing overall toxicity and enhancing therapeutic efficacy. Additionally, our carbon-based nanoparticles go undetected by the immune system.

1st-place

Cameron Hurlburt, Director of Business Development – West Coast (US), LSN | Dennis Ford, Founder and CEO of Life Science Nation, Creator of the RESI Conference Series | Afreen Allam, CEO, SiNON Nano Sciences | Laura Gunter, President, North Carolina Life Sciences Organization


2nd Place – Sanguina

Sanguina is a B2B company with a digital health platform and test kits for point of care and home-based diagnostics that measure key biomarkers of wellness and chronic disease.

The first release on the platform, AnemoCheck, is for anemia management and consists of a patented and FDA-cleared home test kit that uses a fingerstick and smartphone app (patent pending and trade secret algorithms) that noninvasively estimates hemoglobin level from a “fingernail selfie”. Anemia is defined as low hemoglobin levels and is a biomarker of disease/treatment progression. The platform is designed to serve clinical trial, point-of-care and home testing markets for those at high risk of anemia via pharmaceutical, supplement, pharmacy and telehealth B2B customers. Specifically, Sanguina focuses on development of tests for biomarkers that are associated with chronic diseases, often associated with treatments, that have traditionally been inaccessible or invasive.

2nd-place

Claire Jeong, Chief Conference Officer, Vice President of Investor Research, Asia BD, LSN | Dennis Ford, Founder and CEO of Life Science Nation, Creator of the RESI Conference Series | Erika Tyburski, CEO, Sanguina | Maria Thacker, President & CEO, Georgia Bio


3rd Place – Liquet Medical

Liquet Medical is a development stage medical device company. Their first product to market will be the Versus™ Catheter – a localized drug delivery catheter to treat blood clots in the lungs. This device allows for a personalized approach to each patient through real-time biometric data monitoring. It will also speed time-to-treatment and lower hospital costs.

3rd-place

Momo Yamamoto, Investor Research Analyst, LSN | Dennis Ford, Founder and CEO of Life Science Nation, Creator of the RESI Conference Series | John Schindler, CEO & Co-Founder, Liquet Medical | John Newby, CEO, Virginia Bio

If you’re interested in the next upcoming Innovator’s Pitch Challenge, you can apply for the RESI Europe 2024 IPC taking place June 17-19 with a 1-day in-person conference follow by 2-day virtual partnering at Hilton Diagonal Mar Barcelona in Barcelona, Catalonia, Spain. Applications are accepted on a rolling basis, so get your application submitted today!

RESI Europe registration opens at super early bird rates. Register now to save $500 by Friday, April 12.

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