Hot Investor Mandate: VC Firm Invests Up to $10M, Focused Exclusively in New Investments in Oncology Therapies Across the Globe

17 Dec

A global investor exclusively focused on the development of oncology therapies is headquartered in Western Europe; the firm makes selective investments in early-stage drug development companies targeting cancer therapies that can bring solid proof of concept to the table. Typically, the firm invests in incorporated companies from late seed stage to early series B. The investment size will vary, and it can range from 3 to 10 million dollars with the possibility of investing lower amounts for seed stage companies. The firm may make 3-4 investments in the next year, depending on the opportunity. The firm has no geographic restriction and is actively seeking new investment opportunities across the globe.

In the life sciences, the firm is currently seeking new investments targeting the development of oncology therapies, and is open to all types of therapeutic modalities and all indications within the oncology space, including platform technology that has a lead oncology therapeutic product. The firm will typically not invest in medical devices or diagnostics, unless as companion to a therapeutic solution. Project will be evaluated on solid preclinical proof-of-concept (late preclinical stage/pre-IND or early clinical), and will often fund the companies at least up to human proof-of-concept (clinical Phase Ib – Phase IIa).

Representative portfolio companies include: ARCUS Biosciences (Hayward, CA), developing small-molecule and antibody compounds targeting tumor related immune suppression, enhanced APC function and immune cell efficacy; Tusk Therapeutics (Stevenage, UK), developing novel immune modulating antibody therapeutics to harness the immune system against cancer; Octimet (Beerse, Belgium), a spin-out company from Janssen Pharmaceuticals developing a new generation of highly selective MET kinase activity inhibitors with augmented therapeutic index; Convert Pharmaceuticals (Liege, Belgium), developing hypoxia activated pro-cytotoxic small molecules; and Cristal Therapeutics (Maastricht, The Netherlands), developing a versatile nanoparticle platform which allows payload delivery in the tumor micro-environment.

The firm only invests in private companies with experienced management teams and breakthrough potential. The firm most often takes the responsibility to be lead investor, alone or in syndicate as the opportunity demands, and wants to be actively involved in the successful development and growth of the portfolio companies. To this end, the firm has several experts in oncology, intellectual property and drug development on the investment team and available to the portfolio companies.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Hot Investor Mandate: Strategic Venture Arm of Large USA Health System Seeks to Partner With Early-Stage Medtech and Digital Health Opportunities

17 Dec

The strategic venture capital arm and innovation group of a large health system manages both a seed fund as well as a later-stage corporate venture fund, both dedicated to medtech and healthcare IT. In addition, the group also has an incubator and innovation group that looks to develop and integrate IP generated internally and externally that can be leveraged by the health system. Seed investments usually range from $100k – $500k with additional capital reserved for follow on investments, typically allocating up to $1.5M over the life of the investment. Later stage investments are usually in the range of $1M-$2M. The group is flexible in terms of structure but typically refers convertible notes for seed deals and straight equity for later-stage investments. The firm may lead investments or invest with a syndicate and looks to be active in portfolio companies’ development and add value at the board level as well as through integration into the health system.

The firm is exclusively focused on the medtech and digital health/healthcare IT sectors. The group is fairly opportunistic in these areas, but looks for technologies that can be leveraged by the health system. Both pre-revenue and pre-FDA approval devices, as well as commercial/revenue-generating companies, will be considered. The firm has no preference for regulatory pathway and has a particular interest in the cardio space.

The firm has historically focused on startups in the Midwestern United States, however, is looking more broadly and open to companies across the U.S. The group favors strong management teams that are open to working closely together.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Hot Investor Mandate: USA Investment Firm Invests in Global Early-Stage Life Science Companies, With Strong Interest in Human Augmentation

17 Dec

An investment firm with several offices throughout the USA recently closed a new fund and is actively seeking new investment opportunities. The firm is focused on investing in Seed to Series A rounds, with initial check sizes ranging from $2-3M, and $5-10M reserved for follow-on investment. The firm invests in global opportunities.

The firm has a broad interest in life sciences and will consider opportunities in therapeutics, medical devices, diagnostics, and computationally enabled solutions, and is open to different types of modalities and indications. However, the firm does have a strong interest in human augmentation, which includes technologies dedicated to longevity and enhancing quality of life, cognition, enhancement, etc.

The firm’s management team is comprised of entrepreneurs who have been through the investment and fundraising process – the firm seeks companies run by driven entrepreneurs (open to both first-time and serial) whom they can work together based on mutual trust. The firm prefers to lead investment rounds and seek board representation, but is open to co-investing. The firm invests in a small number of companies and seeks to have a very active, hands-on role in their portfolio companies.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Hot Investor Mandate: Venture Capital & Growth Equity Fund Invests Up to $20M in Clinical Stage Therapeutics, Medical Devices, Diagnostics Across All Indications

17 Dec

A venture capital and growth equity firm making investments in life sciences will invest as early as Series A through growth transactions and is currently investing out of their first fund. The firm looks to invest between $10-20M per investment. The firm is looking for companies with clinical data and/or commercial products. The firm has a preference for funding companies that are repurposing existing approved technologies for new indications. The firm is willing to invest in therapeutics, medical device and diagnostics companies.

The firm has a primary focus on pharmaceuticals / therapeutics, and a secondary focus on medical device, diagnostics. The firm is agnostic to indication.

The firm plays an active role in their portfolio companies. The firm will take a board seat with any company in which they invest.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Venture Capital Firms Invest in Therapeutic Technologies Targeting Age-related Diseases in Europe & USA

16 Dec

A venture capital firm and company builder with headquarters in Western Europe and an additional office in the USA is allocating their funds primarily into companies in Europe and North America. The firm works on equity investments and venture creation, and the initial investment size is in the range from $1-5M in the Seed Round and additional $10-15M for subsequent rounds.

The firm invests in technologies that can treat age-related disease and damages associated with aging, such as altered protein homeostasis, cellular senescence, stem cell exhaustion, etc. The firm is primarily focused on therapeutics, but is also considering advanced therapy medicinal products (gene therapy, cell therapy, tissue engineering) as long as they are relevant to the firm’s mission in targeting the basic mechanisms contributing to age-related disease. However, medical devices are currently not an area of focus. In therapeutics, the firm looks mostly at pre-clinical technologies with a validated proof-of-concept. The firm will consider companies in their later stages but prefers working with early-stage companies to provide company building and strategic support.

The firm can work with all types of management teams. The firm places higher importance in the actual science or technology in development as well as solid IP position. The firm seeks to work closely with their portfolio companies and can assist with building and structuring a full management team. As the firm generally comes in as the first institutional investor, they prefer to lead rounds and take a board seat, but are also open to joining strong syndicates.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

USA Seed Fund Focuses on Women-led, B2C Healthcare Companies, Most Interested in Wearables, Software & Products supporting Patients/Caregivers and Aging in Place

16 Dec

A seed fund based in the US has an initial fund of $20 million. The firm typically makes seed investments of $500,000, with a majority of their capital reserved for follow-on rounds. The firm focuses on investing in women-led startups in healthcare. The firm focuses on US startups but will also consider opportunities outside of the US with a US-based entity.

The firm invests in healthcare companies in which consumers are involved in the use of or purchase of the product or service. The firm does not invest in drugs, PMA devices or in purely B2B technologies. Areas of interest include wearable medical devices, software used by patients or their caregivers, products that support seniors in aging in place, and products for wellness and prevention of disease. The firm does not invest in products based on unproven science, and the company needs to be able to demonstrate that the product or technology improved clinical outcomes; however, the firm is open to investing in pre-revenue products.

The firm only invests in companies with at least one woman on the executive team. The firm will invest in companies that face operational risk, but not companies that face scientific risk. The firm would consider investing in digital health companies that have not yet conducted pilot studies with customers provided these companies have a strong IP position.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Early-Stage Therapeutics Investors on the Front Lines of Longevity & Aging

10 Dec

By Rory McCann, Marketing Manager & Conference Producer, LSN

One of the most active sectors in longevity and aging is drug discovery and development. Life Science Nation (LSN) is pleased to introduce the early-stage therapeutics panel at LSN’s newest partnering conference, Longevity, Health & Innovation (LHI). Led by Anastasiya Giarletta, a Principal at R42 Group, the panel will discuss the latest trends in the marketplace that impact how investors source and vet novel therapeutic assets and how today’s climate impacts their strategy to move these necessary products to commercialization. Get to know the panelists and sign up for Longevity, Health & Innovation to begin partnering with investors who match your product and stage of development.

 Moderator: Anastasiya Giarletta, Principal, R42 Group

Anastasiya Giarletta manages an extensive business network spanning FinTech, artificial intelligence and rapidly growing longevity biotech industries in the UK, Silicon Valley and New York. As a specialist in the early-stage longevity biotech ecosystem, she connects and advises venture funds, angels, and entrepreneurs, aligning them with success and growth, as well as organizing and leading collaborative longevity biotech industry events with her company Aikora Health. Previously, Anastasiya’s focus was on financial services, FinTech and venture capital space. Anastasiya holds a degree in Management and Sustainable Development from the University of St Andrews.

Alexandra Bause, Partner, Apollo Ventures

Alexandra is leading the venture creation programs that aim at founding new biotech startups targeting the aging process at a molecular level. She is also managing the pipeline and diligence process for external investment opportunities, predominantly focusing on preclinical stage biotech companies. Before joining Apollo Ventures, Alexandra worked with The Boston Consulting Group where she specialized in biopharma strategy, market assessment and asset diligence. Her PhD studies at Harvard Medical School were focused on investigating the molecular mechanisms that contribute to cellular aging and could be targeted to increase mammalian health span. She is also a trained pharmacist with expertise in pharmaceutics and pharmacology.

Patrick Burgermeister, Partner, KIZOO Technology Capital

Patrick Burgermeister is an expert in life science investing with a double background in molecular biology (Biozentrum Basel) and business administration (HSG Sankt Gallen). He joined Kizoo in 2019 coming from the venture capital group BioMedPartners where he was one of the partners. Moreover, his industry career encompasses also banking (as a senior analyst for pharma/biotech) and pharma (as a senior portfolio manager at Novartis). Patrick supports various biotech companies as a director on their boards, was a successful business developer for early-stage biotech companies and led collaboration and licensing deals with public and private companies. He headed business development at several companies including Apeiron Biologics and BioVersys.

Sergey Jakimov, Executive Board Member, Longenesis

Sergey Jakimov is a founder and advisor to multiple growth-stage startups in Europe and Asia. His main field of expertise is the industrial integration of digital health solutions and novel biomedical technologies, as well as the commercialization of hard IP assets. After graduating with merit from Central European University and Riga Graduate School of Law, Sergey founded two deep-tech ventures, one of which – Koatum – is a biomedical technology company that develops targeted drug delivery systems for dental and orthopedic implants, that is currently in the last round of validation before being launched as a commercial product into the US market. Using his experience in the field, Sergey, as the CEO of Longenesis – a digital health tech company, provides the R&D industry with tools that facilitate the clinical trial process in multiple research and healthcare institutions around the globe. Sergey is also a guest lecturer and co-author of the study program on product commercialization at the University of Latvia, as well as a guest lecturer in Riga Graduate School of Law (Latvia) and Riga Stradins University (Latvia). Recently, Sergey has co-founded LongeVC – an early-stage longevity-focused VC fund, looking to back emerging longevity tech in seed and pre-A stages.

Joon Yun, MD, President & Partner, Palo Alto Investors

Dr. Joon Yun is President and Managing Partner of Palo Alto Investors LP, a healthcare hedge fund founded in 1989. Board-certified in radiology, Joon served on the clinical faculty at Stanford from 2000-2006. Joon has served on numerous boards, and he is currently a trustee of the Salk Institute. Joon is a member of the President’s Circle of the National Academies of Sciences, Engineering, and Medicine. Joon has published dozens of patents and scientific articles. Joon and his wife Kimberly launched the $1 million Palo Alto Longevity Prize in 2013 to reverse the aging process and recently donated $2 million to launch the National Academy of Medicine Aging and Longevity Grand Challenge. Fun fact: Joon has been going to Burning Man consecutively for the past 18 years.

If you’re looking for increased exposure and opportunities to pitch directly to investors at LHI, look no further than the Innovator’s PItch Challenge (IPC). Start-ups can pitch directly to a panel of investors during a live Q&A session. These sessions will provide valuable insights and feedback, as well as build connections between fundraising founders and potential strategic partners. Each company will be provided with a dedicated landing page on LHI’s virtual agenda, which will include their 4-minute pre-recorded pitch video, slide deck, executive summary, etc. Click here to learn more and apply for LHI’s Innovator’s Pitch Challenge.