Hot Investor Mandate 2: Major Biotech Firm Looks Externally for Neurology and Rare Disease Assets

A large biotechnology company headquartered in the USA is continuously looking to expand its pipeline through external partnerships and is open to many types of collaboration, including e.g. collaborative research, equity investments, licensing, or M&A. The company considers opportunities from around the globe.

The firm is currently focused on neurodegenerative diseases, neuromuscular disorders, pain, neuroimmunology/-inflammation, other rare neurological diseases, and adjacencies to neurology such as ophthalmology; and other rare and orphan diseases. The firm is seeking platform technologies (e.g. gene therapy/editing) as well as single therapeutic assets that facilitate the identification and validation of new therapeutic targets, biomarkers and patient segmentation strategies. The firm considers projects from post-lead identification and pre-IND to late clinical stages, with an increased interest in Phase Ib and later projects.

Along this line, the company is also interested in diagnostic tools to utilize biomarkers of interest early in clinical trials. The firm is modality agnostic with respect to therapeutic approaches. The firm evaluates deal opportunities on a case-by-case basis, considering a wide range of opportunities from early academic partnerships to M&A.

The firm principally evaluates opportunities based on three key criteria: transformative (‘moonshot’) solution to unmet medical need, sound scientific basis, and clear clinical development and regulatory pathways.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Investor Mandate 3: Global Venture Firm Invests New $400 Million Fund in Novel Therapeutics and Commercial-Stage Medtech

A venture capital firm with offices worldwide closed a new fund in 2017. The firm predominantly focuses on seed and series A and B investments in early stage biotechnology companies, as well as growth equity investments in medical devices companies. The firm’s typical investment size for early stage companies is $5M-$15M and the firm can allocate up to $35-40M total over the life of an investment. The firm focuses on companies that are based in the U.S., Canada and Europe and is actively seeking new investment opportunities.

The firm’s newest fund closed at $400 million, and will invest in 20‐25 biotechnology companies in the U.S., Canada and Europe.

The firm focuses on novel therapeutics and is opportunistic in terms of subsectors and indications. The firm is interested in novel small molecule and biologic therapeutics that address immuno-oncology, orphan/rare or genetic-based diseases, inflammation, infectious diseases and specific viruses, microbiome, and fibrosis and CNS indications. The firm is also interested in regenerative medicine and gene therapy. In medical devices, the firm is generally agnostic to subsector, but is more interested in revenue-generating devices that address cardiovascular, orthopedic, ophthalmic and neurological disorders. Versant prefers devices with proof-of-concept and strong IP.

The firm prefers that a startup company has a strong and experienced management team or technical experts in the relevant technology. The firm generally is flexible with management teams.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Investor Mandate 4: Crossborder Fund Invests in Pharmaceuticals and Devices, Interested in 505(b) Repurposed Assets

A venture capital and private equity firm based in Shanghai, China manages both US dollar and RMB denominated fund. The firm invests in Series A rounds at $1-2M, though its sweet spot is investing $10-15M in Series B/C rounds. The firm works closely with local provincial Chinese governments, allowing them the ability to bring technology successfully into the Chinese market. The firm will generally not invest in the seed stage, and seeks opportunities globally.

The firm invests in pharmaceuticals and Class II medical devices, including an interest in 505(b)(2) repurposed compounds, as well as healthcare-related industries. The firm is interested in all therapeutic areas and in early to mid development stage companies. The firm focuses on unmet medical needs with a China market potential.

The firm does not have management team requirements. The firm will typically take a board seat post-investment, and has the capability to lead and co-invest.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Get Ready, RESI Partnering Opens Monday, August 21st – New Premier Partnering Plus Is On The Docket

By Natasha Eldridge, RESI Conference Manager, LSN

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On Monday August 21st, Partnering for RESI Boston will open and all the entrepreneurs and investors attending the event will be able to start filling out their dance cards for RESI’s one-on-one meetings.  While RESI Partnering has always been the heart of the event, RESI also offers dozens of educational panels and workshops and also an engaging venue for ad-hoc networking.

The new Premier Partnering Plus will feature deep profiles of investors and strategic players that can be used to ensure attending startups get in front of the most relevant, best-fit buy side players possible.  Below is a partial list of investors who are already signed up to take part.  These investors range from family offices to major pharma players, from local funds to international cross border investors. Entrepreneurs can meet an incredible diversity of global investors at RESI Boston and continue the dialogue 6 weeks later at RESI NYC November 15.

While all attendees can use RESI Partnering to send meeting requests to attending investors, Premier Partnering Plus registrants will have a new unique tool to vet investor fits through viewing full mandate data for each investor.  This additional service will inform entrepreneurs as to what kind of opportunities these investors are most focused on, and for the first time, will also provide entrepreneurs with access to direct contact info.  In a previous edition, we took a closer look at what Premier Partnering Plus adds to the RESI experience.  If you’re already registered and would like to talk about upgrading your registration, please contact us at resi@lifesciencenation.com.

CONFIRMED INVESTORS AND STRATEGIC PARTNERS

Pitch Deck Pitfalls – To Get Investor Meetings, Avoid These Common Errors

By Lucy Parkinson, Director of Research, LSN

The LSN team reviews a lot of pitch decks on behalf of our clients, and we also hear many investor responses to startup presentations. We therefore have a unique window into what catches an investor’s eye, and what makes them lose interest. In this article, we’ll take a look at some common mistakes we’ve seen recently.

 

Tell Your Story

It’s all too easy to fill a deck with information on your science and the market but not have any unifying message that brings this information together. A deck is much more likely to get you a meeting if it tells a cohesive story. What motivated you to start this company? What goal is your company working towards? How did your fellow founders get involved? The answers to these simple questions can build your deck’s story and convince an investor to take a meeting. Remember, investors allocate to people rather than to assets – they need to know what your vision is and why you believe in this company. If you do this right, the investor will begin to believe in your company too.

It’s Not A Science Presentation

We often see pitch decks that are laden with graphs, data and images from preclinical studies. Often, these decks are produced by career scientists who have much more experience in presenting at scientific conferences than in marketing a startup to investors.

It’s important to remember that the purpose of a deck is first and foremost to get an investor interested in meeting with you. Every slide should have some important information that you and the investor can then discuss in more depth if there’s an interest. So for example, your slide might briefly summarize the results of your study or state that you found a positive result, then in conversation with the investor you could share these results in more depth if the investor wanted to see them.

Remember that life science investors, even if they’re not scientific experts personally, have access to expert reviewers who will assess your scientific case in great detail if the investor is interested in your company. Neither the deck nor the meeting has to make that deep scientific case for your startup.

Don’t Forget To Talk Business

Some pitch decks devote a lot of space to demonstrating why the scientists believe that their product will successfully demonstrate safety and efficacy in humans, but reserve little space for talking about the business that the product will power. Be realistic about the investor’s motivation: return on capital. Investors will want to know that you’re looking at the competitive landscape for your product, how your product will compete with the current standard of care (or any late-stage assets that might become a new standard of care), and how many patients your product can reach.

Don’t Miss The Exit

Investors will also be focused on how/when your company might be able to exit. Show the investors some comparable companies that IPOed or were acquired recently. In our experience, early stage biotechs benefit from starting discussions with strategic partners as early as possible – how are you positioning the product to such partners to align with their pipeline needs?

Don’t Lose Focus

Early stage biotech companies are often formed around several assets, either related via an underlying platform or created by the same scientist or academic institution. Many new entrepreneurs therefore assume that investors will be interested in the breadth of their portfolio as an opportunity to get several “shots on goal”. However, our experience is that investors generally prefer to see a clear focus on 1 or at most 2 highly promising lead programs. It is useful to mention that you have other assets as well – many strong pitch decks include a ‘Pipeline’ slide that shows all the company’s assets and the stage of development that they’ve reached – but investors primarily value the company according to the development of a lead program.

If you’re interested in getting some feedback on your deck and your investor outreach campaign, we’d be happy to provide a free consultation – you can find more details here.

Need Seed Stage Device Capital? Meet the Medtech Angels at RESI Boston

By James Huang, Research Analyst, LSN

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With medical technology entrepreneurs facing a challenging capital landscape, angel capital remains a vital source of early stage funding in the sector.  According to studies by the Angel Resource Institute, of every angel dollar invested in the USA, nearly 20 cents goes into healthcare and life sciences.  In recognition of the importance of angel financing to early stage companies, RESI features two angel panels, and today we would like to announce our Medtech Angels panel for RESI Boston.  If you’re interested in how to pitch to an angel group, what makes a medtech opportunity suitable for angel investment, or how angels work with their portfolio companies to hit subsequent milestones and follow-on raises, this panel is for you.

LSN has brought together five highly experienced angels who have a focus on medical technology investment.  The participants are:

Hot Investor Mandate 1: Southeast Family Office Looks US-Wide for Medtech Deals

A family office based in the southeast USA focuses its investment interests in healthcare, real estate, energy, and IT. The firm makes equity investments ranging from early-stage to full on commercialization, but also provides debt and convertible loan financing. The firm generally looks for USA-based opportunities but may consider deals outside of the USA and has a track record of working with companies globally. The firm seeks to make approximately 6-10 investments per year.

In the life sciences, the firm has a strong interest in medical device and diagnostic companies. The firm considers healthcare IT opportunities to a lesser degree, and will not consider biopharma companies for the most part. The firm is open to devices of all FDA regulatory pathways including 510k and PMA. The firm is very opportunistic regarding the company’s stage of development and will consider products that are both on- and off-market.

The firm is looking for privately held companies backed by an experienced management team. Companies should have a strong exit strategy, including having a direct line of contact with strategic or financial buyers. The firm is open to both leading and co-investing in a financing round.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com