A venture capital firm who has raised over $1.9 billion is currently making investments out of its vintage 2016 $616 million fund. The firm seeks opportunities to transform patient’s lives by working at the intersection of science, medicine, strategy and business. The firm typically makes equity investments in the range of $40-$50 million in the companies it builds. Allocations are allocated in milestone driven tranches as their companies progress to and through clinical trials. The firm is geographically focused with portfolio companies near their offices in Boston and San Francisco.

The firm is currently building companies that will develop therapeutics across a diverse set of modalities: small molecules, biologics, gene therapy, and cell therapy. In terms of indication the firm is most interested in areas of oncology, cardiovascular, neurology, rare diseases, metabolic disorders and immunology. The firm typically builds companies with early discovery stage and pre-clinical assets that are within 3 years to filing an IND. The firm is focused on building product engine companies and typically does not build single asset companies, but will consider business development opportunities around assets relevant to companies it is building.

The firm builds companies with highly experienced management teams and focused recruiting great management teams for its companies. The firm acts as a long term strategic investor and takes a board seat into companies following investment.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

A single family office with over 45 years of entrepreneurship experience in the life sciences sector invests broadly in healthcare and is open to companies of all stages. The size of investment can largely vary depending on the stage of the company. The firm has invested mainly in USA-based companies but is open to global opportunities.

The firm has a broad interest in healthcare and is most interested in private biotech companies, with a few investments in medical device companies as well. In therapeutics, the firm’s sweet spot is from pre-clinical to late-stage II, with particular interest in assets with accelerated or de-risked regulatory pathways. The firm is interested in all indications, including oncology and immunotherapies. The firm also considers gene therapy as an area of high interest. In terms of medical devices, the firm is most interested in minimally invasive devices and is open to 510k and PMA regulatory pathways.

The firm seeks to work with experienced management teams with strong scientific expertise. Another important consideration is other investors that have participated in the financing. The firm invests in both public and private companies and will most likely seek board representation.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

A leading investment and advisory firm with USA and China offices is currently interested in investing in privately held companies in the TMT (Tech, Media, and Telecom) and healthcare sector. The firm currently manages two funds, a $150M VC fund which only invests in China, and a $50M early-stage fund that focuses on investments into US start-ups. The firm is planning to raise a second and much larger US fund in next 12 months. On average, the initial size of investment is in the $2-3M range. The firm is looking for attractive investment opportunities in North America and China.

The firm is a flexible and opportunistic investor that is currently considering therapeutics, medical devices, diagnostics, genomics, healthcare services and healthcare IT companies. With respect to medical devices, the firm is interested in devices with all FDA regulatory pathways, including 510k, PMA, and software-enabled devices.

The firm prefers to act as the lead investor but is also open to co-investing. The firm will neither seek a board seat nor seek distribution rights.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

A private, Boston-based family office is currently interested in investing into privately held companies in the life science space. The firm is very flexible and nimble due to its capital base and is able to make investments ranging anywhere from $500,000 to $20 million and more into a given company. The firm is currently looking for companies located throughout the United States. The firm generally would only act as a co-investor from companies located outside the United States.

The firm is open to sectors and subsectors in the life science space including healthcare IT, medical devices, and diagnostics. For devices and diagnostics, the firm is looking for companies that have significant clinical data. Current portfolio companies include those working with antiviral therapies, cloud-based laboratory services, anticoagulant therapies, orthotics and prosthetics, medical devices and diagnostics for male lower urinary tract symptoms, and therapeutics for dermatology and aesthetics.

The firm is looking for companies with experienced manage teams and generally looks to take a board seat following investment. Due to the firm’s capital base they can be more flexible in terms of investment timeframe and have a longer exit horizon than other investors.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

A foundation that focuses on funding for core, academic research in oncology is actively seeking opportunities in the early stage landscape. As one of the leading funders of academic oncology research in the United States, it has funded 60 scientists, generating 57 scientific innovation and invention disclosures, 16 spinoff companies of which 1) five were acquired, 2) one went public, and 3) five licensed their technologies to larger companies – an outstanding track record at the very earliest stages of investment.

The foundation also operates a $25 million fund focused on capitalizing translational opportunities – that is, the commercialization of academic technologies / financing the first round of commercialization. The fund provides funding to early-stage translational companies via $1M – $5M recoverable grants which are essentially structured as convertible notes with 1) no expiration date and 2) no liquidity preference. Such grants do not reflect as debt on the investee’s balance sheet, and are converted to equity at very reasonable terms only in the event the valuation of the company increases about a pre-determined level.

The foundation has also helped to organize, and is a General Partner of a $350 million fund focused on pre-clinical, Phase I, Phase II, and Phase III investments. The foundation expects to execute a first close by June 2018, and a second close by early 2019.

The foundation issues grants primarily within the United States, and via another subsidiary fund throughout Asia. The aforementioned funding vehicles invest primarily within the United States, but have a small allocation for foreign investments.

Sector interests include drugs, medical devices, and novel approaches. The firm is also open to funding technologies designed to accelerate cancer research and drug development, such as novel drug discovery tools or algorithms. By using its 3 funding vehicles, the firm finances projects from the early discovery stage through to Phase III clinical trials. The foundation considers projects in any type of cancer.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

A USA-based international investment group is looking to make equity investments into early stage companies in the life science and technology sectors. The firm makes investments generally ranging from $50,000 to $1,000,000 into companies and is generally involved in 2-4 deals per year. The firm is willing to consider companies around the globe.

The firm is generally open to all areas within the life sciences industry. The firm generally makes investment in the seed and series A stages and as such they are generally looking for companies with pre-clincal or early prototype technologies.

The firm is looking for private or publicly held companies with motivated management teams. The firm looks to take board seats into companies on a case by case basis.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

A venture capital firm allocates capital sourced from family offices based in Europe and is also raising a seed fund focusing on investments in the biopharma space. The firm’s principals generally participate in seed to Series A financing rounds, making equity investments in the range of € 0.1-2 M. The firm invests globally with a focus on North America and Europe.

The firm seeks early stage biotech companies in Europe and North America that develop first or best in class therapeutic agents, currently in pre-clinical and phase I, across all indications. The firm is also considering select later-stage opportunities in medical devices, diagnostics, or healthcare IT as requested by family offices for direct investments.

The firm looks for startups that will be highly attractive for large companies after proof of concept in man. The firm is open to working as early as the time of technology transfer, with academic founding teams that demonstrate strong technical expertise in their field and the willingness to embark complementary management, including a proven CEO.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com