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Hot Life Science Investor Mandate 4: US Based Hedge Fund Seeking Range of Therapeutics Opportunities Globally

19 Mar

A biotechnology-focused equity hedge fund based in Western US is looking to invest in therapeutics space. The investment size can vary greatly and the fund is very flexible depending on each company’s needs. The fund is geographically agnostic and looks to invest globally.

The firm is highly interested in biotech therapeutics. The fund is extremely opportunistic in terms of subsectors and indications and will consider companies at all stages of development. The fund recently invested in a European-based company developing small molecule therapeutics for CNS diseases and a US-based company developing therapeutics for oncology.

The firm seeks a company with a strong and experienced management team or technical experts in the relevant technology. The fund will require either a board seat or observer status.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Life Science Investor Mandate 1: Family Office Seeking Early Stage Oncology Opportunities

12 Mar

A specialist investor that is funded by private capital was founded in 2011 and has operations in Luxembourg, Belgium and USA. The firm exclusively focuses on investments in early-stage drug development companies targeting cancer therapies. The firm is most interested in companies from late seed stage to series A. The investment size will vary, and it can range from a few hundred thousand dollars up to a couple of million dollars. The firm may make 3-4 investments in the next year, depending on the opportunity. The firm has no geographic restriction and is actively seeking new investment opportunities across the globe.

In the life sciences, the firm is currently looking for new investments targeting the development of oncology therapies. The firm will not invest in medical device or diagnostics. The firm typically invests in companies with solid preclinical proof of concept (late preclinical stage/ pre-IND), and it will fund the companies at least up to human proof of concept (clinical phase Ib/ phase IIa). The firm prefers to invest in companies with small pipeline and a clear regulatory pathway. Historically, the firm was active in companies targeting immune therapy and tumor cell metabolism within the oncology field.

The firm primarily invests in private companies with experienced management team and breakthrough potential. The firm looks to be a lead investor and may take a board seat.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Life Science Investor Mandate 2: Russian Corporate VC Fund Seeking Life Science Investments Globally

12 Mar

A venture capital fund financed entirely by a Russian pharmaceutical company is looking to make investments ranging from $5-$15 million in companies in the life science space. The firm could make as many as 2-3 investments over the next 6-9 months and is willing to allocate to companies around the globe. Besides equity investment, the firm would consider local licensing opportunities for Russian/CIS market.

The fund is currently looking for companies developing therapeutics and is open to both small molecules, biologics, and cell/gene therapy. The firm is more interested in companies working with single assets though they are also willing to consider platform technologies. Indications of interest include Oncology, Inflammation, Neurodegenerative diseases, Orphan genetic diseases, Critical care, Regenerative medicine and Cardiovascular. The firm looks for companies that have at least reached in-vivo proof of concept with their lead asset.

The fund is looking for privately held companies and prefers companies with experienced management teams in place. The firm looks to act as a value-added investor through their strategic alignment with its parent company, and looks to take a seat on the company’s board on a case by case basis. The firm is willing to both lead and co-invest in financing rounds.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Life Science Investor Mandate 3: South Korean Pharmaceutical Company Seeking to In-License Clinical Stage Therapeutics in Neurology, Hepatology, and Gastroenterology

12 Mar

A South Korean pharmaceutical company that specializes in Gastrointestinal, CNS, and Metabolic products is actively searching for promising therapeutic candidates under development around the world to incorporate into its pipeline. The company is flexible in terms of the structure, but mostly in-licensing or co-development. The company is interested in world wide/major territories such as the US, EU, APAC, and East Asia. 

The firm is currently seeking promising therapeutic candidates to incorporate into its pipeline. The company is most interested in neurology, hepatology, and gastroenterology. However, the firm is also interested in other therapeutic areas that address large unmet medical needs. The company will look at both small molecules and biologics and will consider only NCE or NCE-like molecules (such as repositioning molecule, new indication, etc). The company prefers assets in phase I, II, or IND-ready. However, the company will also look at assets in phase III and NDA stage.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

February Mandate Roundup: 79 Investors from 13 Countries

5 Mar

By Lucy Parkinson, Senior Research Manager, LSN

lucy 10*10This February, LSN’s research staff in Boston has seen not only a lot of snowfall, but also a lot of mandates. We spoke with a total of 79 investors during this short, snowy month. As Figure 1 demonstrates, we had conversations with every type of life science investor that LSN tracks:

 

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Figure 1 | Source: LSN Investor Platform, Data as of February 28, 2015

These investors are also diverse geographically; although most are based in the U.S., we also spoke to investors in 12 other countries around the world (see Figure 2). Fourteen of these investors are based in Asia, a region often untapped by entrepreneurs located outside of it; LSN has discovered through our mandate interviews that most Asia-based life science investors are looking beyond the region for investment opportunities. 

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Figure 2 | Source: LSN Investor Platform, Data as of February 28, 2015

As you can see in Figure 3 below, almost half of these investors are interested in opportunities globally. The rest focus on one or several specific geographic regions, with the U.S. being the most common.

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Figure 3 | Source: LSN Investor Platform, Data as of February 28, 2015

The investors we contact have varied interests across the life sciences; some invest opportunistically in any part of the field, whereas others focus on a particular area of speciality. In February 2015, the diagnostics sector attracted interest from the greatest number of investors, followed by medical technology and biotech therapeutics (see Figure 4). We’ve found from our discussions with investors that diagnostics companies receive attention from both medtech investors interested in diagnostic devices and imaging technologies, and also from biotech investors interested in molecular diagnostics and personalized medicine. In addition to these three sectors, we also speak to investors who are interested in engineering companies (including companies developing lab equipment or healthcare IT products), biotech R&D companies (including CROs), and other biotech opportunities such as industrial biotech or agricultural biotech.

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Figure 4 | Source: LSN Investor Platform, Data as of February 28, 2015

LSN focuses on researching investors who are open to early stage life science opportunities, and those represented in February’s mandates are no exception. The investors we spoke with are most likely to be focused on companies that have successfully passed through the IDE/IND stage and have products in early clinical trials. However, we also spoke to many investors who look at other opportunities, including those offered by very early stage companies as well as late stage companies that have begun marketing their product. Figure 5 shows the stages at which diagnostic and medical technology investors prefer to invest:

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Figure 5 | Source: LSN Investor Platform, Data as of February 28, 2015

Figure 6 shows the stage at which biotech therapeutics investors prefer to invest. In this sector, you can see that interest in fully developed products drops off sharply, due to the much longer development cycle involved.

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Figure 6 | Source: LSN Investor Platform, Data as of February 28, 2015

While this roundup provides an overview of the information we have recently gathered regarding investor interest, we collect many other details that help us identify suitable opportunities for each investor, including which indication areas and technological approaches the investor focuses on, and what kind of financing rounds the investor is open to participating in. These details are invaluable to a life science company looking to find the right investor fit. We look forward to speaking with more life science investors during March and beyond.

Hot Life Science Investor Mandate 1: Corporate Venture Capital Firm Seeking Pre-Clinical Stage Novel Platform Therapeutics

5 Mar

A large European pharmaceutical company recently opened a US office to invest out of a $130 million evergreen corporate venture fund. The fund is interested in life science opportunities globally, and expects to make 3-4 new investments per year. The fund typically invests about $10 million over the life of an investment.  The fund is typically a lead investor, and participates in syndicates with other investment firms.

The fund seeks to invest in companies with preclinical assets.  The firm prefers to invest in companies developing therapeutic platform technologies.  The fund is only interested in novel technologies; while the fund will consider investing in any form of therapeutic technology, gene therapy and regenerative medicine are particularly of interest.  The fund is focused on investing in oncology, but will also consider opportunities in other indication areas.

The fund invests in technologies of strategic importance to its parent company. The fund only invests in privately held companies.  The fund typically does not invest in single asset opportunities; only companies with multiple pipeline assets are of interest.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Life Science Investor Mandate 2: Chinese PE Firm Looking Globally for Medical Device, Diagnostic and Healthcare IT Opportunities

5 Mar

A private equity firm that was founded in 2004 and is headquartered in China is currently seeking new opportunities. The firm provides venture capital and growth capital to early-stage companies across various industries, including life sciences, energy, Internet and software. The firm is interested in all types of life science companies except drug development. The allocation size will vary, but the firm has the capability to allocate up to $20 million per company, depending on the opportunity. The investment is typically in form of equity, but convertible loan will be considered as well. The firm has an emphasis on technologies and products, and it is currently seeking new investment opportunities globally.

The firm is currently seeking to invest in medical device, diagnostics, biotech R&D services and healthcare IT sectors. The firm is very opportunistic in terms of subsectors and indications. Currently the firm will not invest in companies targeting drug development.  The firm will consider companies at all stages of development, from pre-clinical stage all through to commercial stage; however, the firm is most interested in companies in the pre-commercial stage.

The firm primarily invests in early-stage private companies. The firm does not have specific requirements for companies’ management team or revenues. The firm will take a board seat post-investment.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com