Unlocking Preclinical Success: Learn from Radyus Research’s Workshop

22 Jun

By Candice He, Vice President of Business Development, Global Investment Strategist, LSN

Dear RESI Community,

We are excited to present an exclusive opportunity to delve into the world of preclinical development and gain valuable insights from Radyus Research, one of our esteemed sponsors of RESI Boston June. Radyus Research hosted a captivating workshop titled “Maximizing Pre-clinical Development Success for VC-Backed Startups Through CRO Partnerships,” and we are delighted to share the recording with you.

Maximizing Pre-clinical Development Success for VC-Backed Startups Through CRO Partnerships

Preclinical development is often complex and non-linear. You need to coordinate several CROs, CDMOs and an army of consultants while project managing it all. Join our workshop as we discuss best practices in finding and engaging with the right CRO partners to increase your chance of getting to IND faster, with greater success. Choosing the right CRO partner not only saves you time, money and whole lotta nerves, but gets the attention of investors. Investors appreciate well thought out, fully integrated product development plans that clearly identify value inflection milestones, contingencies, and mitigation strategies. The right CRO partner will make you look good in the eyes of investors—make sure to take advantage of that!

  • Marta New, PhD, MBA, CEO, Radyus Research (Moderator)
  • Omar Khalil, PhD, General Partner, Sante Ventures
  • Livija Deban, CSO, Prokarium Ltd
  • John Foglesong, MBA, CEO, Grannus Therapeutics
  • Paul Tebbey, PhD, MBA, Board Member & Advisor, Radyus Research

We invite you to watch the recording of this insightful workshop and unlock the secrets to enhancing preclinical development outcomes. Gain practical tips, expert strategies, and real-world examples that can propel your venture forward. By leveraging the knowledge shared in this workshop, you can optimize your approach to CRO partnerships and position yourself for greater success.

Moreover, if you are an industry expert interested in hosting workshops at future RESI conferences, we invite you to join our exclusive group of sponsors. Showcase your expertise, connect with a diverse community of early stage life science investors and innovators, and gain unparalleled visibility. Together, we can shape the future of the life science and healthcare sectors.

For sponsorship inquiries and to learn more about the RESI Conference, please visit our website or contact our team today at resi@lifesciencenation.com. Join us in fostering collaboration, driving innovation, and revolutionizing the future of healthcare.

Hot Investor Mandate: USA-Based VC Firm Invests in Therapeutics & Medical Technologies in North America, Europe, Asia With Strong Interest in Oncology and Rare Diseases

22 Jun

A global venture capital and commercial development firm based in the USA is currently investing out of its sixth fund. In addition, the firm recently closed on a new fund through its Specialized Funds business unit, and is investing in companies domiciled in Singapore, Hong Kong and China. The firm generally looks to support companies with lead assets that can reach high value inflection points in 3-4 years and will consider opportunities in US, Canada, Europe, Singapore, Hong Kong and China.

The firm is currently seeking companies developing therapeutics or medical technologies to treat true unmet medical needs. The firm is therapeutic area agnostic, although the firm has historically been most active in immunology, oncology, and rare diseases. The firm typically prefers to invest in Series A/B rounds with a preference for lead assets between 18 months pre-IND and Phase 2a. Within devices, the firm generally prefers to invest in later stage opportunities, particularly those devices that have received market approval with early revenue.

The firm does not have any specific requirements for a firm’s management team. The firm is an active investor and seeks a director or observer position on a company’s board.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Hot Investor Mandate: Strategic Corporate Venture Fund Seeks Early-Stage Therapeutics & Platform Technologies in CNS, Inflammation, and More

22 Jun

A strategic corporate venture fund of a pharmaceutical company actively invests in early-stage biotech companies that are of strategic interest to the parent pharmaceutical. The firm invests in global opportunities, but focuses primarily on North America and Europe.

The firm invests in early-stage therapeutics and platform technology companies. The firm’s main areas of interest include immunology and inflammation, kidney disease including transplant, serious diseases treated in hospitals, neurodegenerative disease, and rare disease. Regarding platform technologies, the firm is interested in drug discovery technologies for small molecule, peptide, nucleic acid, and other novel modalities, delivery systems (CNS, kidney disease), and cell therapies (excluding those targeting oncology). The firm invests primarily in pre-clinical opportunities, and can consider those as early as discovery stage. The firm does not actively seek opportunities in medical devices, diagnostics, or digital health at this time.

The firm has no specific company or management team requirements. The firm, alongside with the parent pharmaceutical company and an in-house Open Innovation Center, can help companies beyond capital. The firm can offer scientific expertise, and is able to collaborate on early stage proof-of-concept experiments and projects with emerging companies.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Hot Investor Mandate: Venture Fund Formed by High-Net Worth Individuals Invests in Novel Devices, Diagnostics, and Digital Health With Focus in USA and China

22 Jun

A venture fund formed by a group of high net-worth individuals in China has offices in USA and China. The fund is currently seeking investment opportunities globally with a focus on China and the US. Projects based in Canada, Germany, and Switzerland may also be considered.

The fund pays close attention to investment opportunities from seed and early stages to growth stage. For seed and early stage projects, the fund makes investments in convertible notes and equity and is flexible on investment size. For growth stage projects, the fund makes equity investments of US$1-5 million in businesses with valuation of up to US$18-20 million. Due to its evergreen fund structure, the fund takes a long-term approach to investment. The fund typically syndicates in a financing round and would like to partner with local co-investors in case of overseas investments.

The firm focuses on high-growth fields in medical devices, diagnostics, digital health, and consumer products. The firm is agnostic to disease areas. In diagnostics, the fund is interested in portable imaging devices, high-intensity ultrasound, point-of-care diagnostics, and molecular diagnostics. In digital health, the fund is interested in technologies that can be applicable to the Chinese market, such as connected devices, telemedicine, and patient-physician platforms. In consumer products, the fund in interested in OTC, nutrition and dietary supplements that have proven efficacy and are on market.

The firm is looking to work with serial entrepreneurs from seed and early stages to growth stage to form complete and strong teams. The fund typically cooperates with local co-investors who play a supervisory role in overseas operations.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Hot Investor Mandate: Medtech Company Strategically Invests in Medical Device Companies, Particularly Implantable Devices in Early and Late Development Stages

22 Jun

A high-tech enterprise with offices in Europe and Asia focuses on the R&D, manufacturing and sales of implantable medical devices. The firm’s line of products include dural substitutes and cranioplasty implant for neurosurgery, and more. Now, the firm is actively seeking external opportunities for investment and other types of strategic partnerships. With regard to investment, the firm will generally invest within one million dollar per deal. The firm is open to global opportunities.

The firm is interested in expanding their business by investing and partnering with medical device companies. The firm is not interested in therapeutics, diagnostics, or digital health. The firm is most interested in Class III implantable medical devices, but will not exclude Class I or II. The firm is open to working with companies across all stages of development.

The firm has 2 main focuses within medical devices, according their stage of development:

(1) Products at early development stage: the firm is open to investing in companies at the idea-level, or those with a prototype that have not yet started clinical trials. In addition to direct equity investment in these stages, the firm is also interested in accelerating the path to market by helping with product development, regulatory and preclinical tests. The firm can act as a lead or co-investor.

(2) Products at later stage: For products that have demonstrated efficacy through clinical trials with patients, the firm is open to exploring beyond direct investment, such as joint venture, licensing, co-development, etc. The firm can provide strategic value to these companies and also assist with China market entry.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Congratulations to the Top 3 IPC Finalists at RESI Boston June 2023!

15 Jun

By Claire Jeong, Chief Conference Officer, Vice President of Investor Research, Asia BD, LSN

Last week, Life Science Nation hosted RESI Boston at the Westin Copley Place, for which over 700 attendees registered.

This time, we had 50+ companies from 10 different countries participate in the Innovator’s Pitch Challenge (IPC). As with the usual IPC format, all finalist companies pitched in front of a judging panel and exhibited a poster showcasing their technology in the exhibit hall. All attendees were provided with “RESI Cash”, which was used to vote for their favorite Innovators. IPC winners will receive complimentary RESI tickets valued up to 12K for the future RESI conference.

Here are the Top 3 IPC finalists who secured the most RESI Cash and were crowd favorites at RESI.

1st Place – Thrive Bioscience

Claire Jeong, Chief Conference Officer, Vice President of Investor Research, Asia BD, LSN | Thomas Forest Farb-Horch, CEO & Board Director, Thrive Bioscience | Dennis Ford, Founder & CEO, LSN

Thrive Bioscience, founded in 2014 and based in the Boston area sells a family of instruments and software that provide previously unavailable data, imaging, analytics, and automation for live cell biology. Thrive is providing automated, extensive, and comparable images and data sets on live cells that are needed for artificial intelligence, machine learning, data mining, improved processes, and breakthrough insights. Thrive is also developing and delivering software modules for key drug discovery workflows that use machine learning to improve experimental assays and research insights. Thrive has raised $34M to-date and is in the last few weeks of closing an oversubscribed $9.25m Series B Convertible Note. Thrive is seeking $5M of financing for an acquisition of a small profitable company and expects to conduct a $15M Series B this year. Thrive has sold and received orders for 75 of its automated live cell imaging instruments, with a price range from $120k to $275k. Thrive has limited competition and has filed 86 patent applications of which 28 have issued. Even though live cells and tissues in culture are key to biomedical research, the collection and analysis of data on live cells has been inefficient, insufficient and non-comparable. Thrive instruments solve these problems for applications that include drug discovery/development, cancer research, in vitro toxicology, infectious disease research, growing stem cells, and regenerative medicine.

2nd Place – Clinials

Emily Thompson, Marketing and Community Lead, Clinials | Maree Beare, CEO, Clinials | Karen Deyo, Director of Product, Israel BD, LSN | Dennis Ford, Founder & CEO, LSN

Clinials is an AI driven participant recruitment platform, solving the problem where 80% of clinical trials fail to meet enrolment deadlines. Clinical trials are costly necessities for research and development (R&D) of novel devices and treatments, yet with more than half failing to finish they become even costlier for pharmaceutical companies. Without R&D we wouldn’t have products like birth control or cancer treatments, this is why fixing the problem of clinical trials being unable to recruit participants is so important.

Clinials’ platform works with AI, converting complex trial protocol into plain language anyone can understand. We’re also speaking to participants when they’re ready to sign up for a trial, unlike the old methods which call databases of uninterested patients out of the blue. Clinials started when my husband enrolled in a clinical trial and was not only drowned in paperwork but had a difficult time understanding the trial despite working in health. Our constructive methods are working for vaccine, diabetes, chronic pain and a host of other therapeutic trials which had previously failed in recruitment.

3rd Place – Untech

Candice He, VP, Business Development & Global Investment Strategist, LSN | Rubén C. Salim Brovia, CEO & Co-Founder, Untech | Alberto N. Ramos Vernieri, CTO & Co-Founder, Untech | Dennis Ford, Founder & CEO, LSN

Untech Inc is a biotech company that has developed a proprietary breakthrough medication for chronic wounds. This dramatic problem affects more than 120 million patients in the world and there is no definitive solution available. After 15 years of research, Untech has developed a unique all-in-one solution that heals these wounds. The product is expected to enter the global market in 2026. Series A is currently open. Chronic wounds, like diabetic, venous and pressure ulcers are complex injuries that do not heal, often leading to amputations. The FDA considers chronic wounds as an Unmet Medical Need because of the increasing number of patients (diabetes, life expectancy and obesity), the huge disease severity, and the lack of efficacy of the available treatments (60% of patients take more than 1 year to heal). Based on a novel approach, Untech has developed a gel that, applied directly to the wounds, attacks all the causes at the same time, achieving healing, and making it the most promising solution for the patients. It has the potential to accelerate the healing time from years to months, drastically reduce the probability of amputation and allow patients to remain ambulatory. The global wound care market was over USD $18B in 2022 (CAGR: 6.2%). Currently, Untech is starting Clinical Phase I, has the patent granted in the US and finalized in 45 countries the national phases of the IP process (90% of global market).

If you’re interested in the upcoming Innovator’s Pitch Challenge, apply to the IPC for RESI Boston September 18-20. Pitching will take place on the in-person day, September 18th. Applications are accepted on a rolling basis, so get your application submitted today!

Deadline: Wednesday, August 9

RESI Boston September 2023 registration opens at super early bird rates. Register now to save $500 by Friday, June 30.

Introducing IPC Judges at RESI Boston June

1 Jun

By Momo Yamamoto, Investor Research Analyst, LSN

After announcing RESI Boston June’s IPC finalists last week, LSN is excited to announce our IPC judges! Our judges will be participating in 14 IPC sessions taking place all day on June 5th at the Westin Copley Place with 50+ companies pitching. Representing investment and industry experts of therapeutics, medical devices, diagnostics, and R&D and life science tools, IPC judges will hold a Q&A session following each pitch. Company poster boards will also be available to view at the RESI Exhibitor Hall, so don’t worry if you can’t attend a session! All registered attendees will receive “RESI Cash” to “invest” or vote for their favorite companies. The Top 3 companies with the most votes will be announced at the end of the day and will receive a prize along with a feature in the LSN newsletter!

Take a look below for to see who is judging!


Christopher Aleong
Managing Director, North America
BioEngine Capital

Jay Batchu
Analyst
Xontogeny

Alexandra Bause
Co-Founder & Venture Partner
Apollo Health Ventures

Rick Berenson
Director – Executive Board
Mass Medical Angels

Randy Berholtz
Senior Advisor
Mesa Verde Venture Partners

Kumar Bhargava
Managing Partner
PharmaCatalyst

Barri Blauvelt
Investment Advisor
Tamer Group

Karthik Bolisetty
Senior Associate
Gilde Healthcare Partners

Rebecca Brandes
Managing Director
Agilent Technologies

Lee Burnes
Senior Vice President, Global Research & Development
Avanos Medical

Jeffrey Champagne
Screening Committee
Boston Harbor Angels

Bruce Cohen
Venture Partner
Xeraya Capital

Alex de Winter
Vice President of New Ventures
Danaher Corporation

Ronald Dorenbos
Principal
Charles River Laboratories

Bettina Ernst
Director
BERNINA BioInvest

Marissa Fayer
U.S. Partner
Goddess Gaia Ventures

Justin Feng
Senior Associate
MRL Ventures Fund (MRLV)

Daniel Franke
Principal
M Ventures

Tom Gibbs
Director
Debiopharm Innovation Fund

Tai Harada
Vice President
Fast Track Initiative

Michael Huang
Managing Partner
Taiwania Capital

Hanuman Jampani
Founder & President
Samrus International

Anil Jina
Executive in Residence
Iaso Ventures

Jennifer Jordan
Venture Partner
iGlobe Partners

Adam Kundzewicz
Executive Director
Boehringer Ingelheim Venture Fund

Seo Lee
Director
SV Investment

Carla Lema Tomé
Search & Evaluation Lead
Spark Therapeutics

Jeffrey Moore
President
MP Healthcare Venture Management (MPH)

Ahmed Mousa
Business Development Executive
Tamer Group

Iris Ohrn
Investment Adviser
Business Region Goteborg

John Pennett
Angel Investor
Mid Atlantic Bio Angels

Jon Popke
Member
Mid Atlantic Bio Angels

Kou Qin
Investment Principal
Eisai Inc.

Chandra Ramanathan
Global Head, Innovation Hubs
Danaher Corporation

Rachel Rath
Director, BARDA Alliance
Johnson & Johnson Innovation

Brock Reeve
CEO and Co-Founder
Eos BioInnovation

Jack Resnick
Inception Program Specialist
NVIDIA VC Alliance

Stephanie Rusinkiewicz
Sr. Manager of Business Development & Licensing, Surgical Innovation, Hernia & Wound Management
Medtronic

Sara Secall
Investment Director
Inveready Asset Management

Colin Sheehan
Associate Director, Ventures
Orange Grove Bio

Jill Sorensen
Chief Operating Officer
Medical Technology Enterprise Consortium (MTEC)

Avi Spier
Director, Strategic Alliances
Novartis

Christopher Tan
Executive Director, Search & Evaluation, Business Development & Licensing, ID & Vaccines
Merck & Co., Inc.

Mark Tang
Managing Director
Good Health Capital

Wei Tao
Board Director & Chair, Bio/Genomics
Life Science Angels

Hung-Loi (Lloyd) Tran
Partner
Transpacific Venture Capital Partners

Jingjing Wang
Senior Associate
Lightstone Ventures

Tim Xu
Senior Director, Business Development, Search & Evaluation
Karuna Therapeutics

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