By Gregory Mannix, Vice President International Business Development, LSN
One of the highlights of the RESI Boston First Coast Innovators’ Gathering (which features 16 top Tech Hubs from the US’s Northeast Corridor) is the RESI Pitch Challenge. After reviewing dozens of applications submitted to the Expert System by the constituent companies from these great programs, the LSN Review Committee has selected 9 companies as finalists to pitch at RESI before a panel of 5 investors. See below to meet these innovative startups.
The Pitch Challenge is a fantastic booster for these early-stage companies, providing the chance to pitch to a top line-up of investors, getting valuable questions and feedback that will help them hone their pitching skills, plus the chance to follow up with the investors on the panel after the conference is finished.
Good luck to all the RESI Pitch Challenge participants!
By Claire Jeong, Director of Research, Asia BD, LSN
In one of our recent newsletters, Dennis Ford, CEO of Life Science Nation, wrote about the Redefining Early Stage Investments (RESI) Conference series’ expansion into Asia Pacific. LSN has established a global partnering ecosystem, and by bringing RESI to Asia we are forming a bridge between promising early-stage innovation and investors/strategic partners. Last month, several colleagues and I traveled to different parts of Asia with the ultimate goal of expanding LSN’s network, promoting the inaugural RESI Asia (11/12 Shanghai & 11/14 Taipei), and identifying synergies with various groups in the life science industry, as well as attending BIO Asia Taiwan.
I had the privilege of presenting a high-level overview of Life Science Nation and RESI to a very intriguing gathering in South Korea called “Innovative Medicine Salon”. The Innovative Medicine Salon started in 2012 in Daejeon – one of South Korea’s leading hub in science and technology – as a small gathering of life science professionals (scientists, professors, doctors, etc.) who would organize talks highlighting various thought-provoking topics regarding the theme of “innovative drug discovery”. As South Korea’s biotech ecosystem rapidly grew, the Innovative Medicine Salon continued to expand into other key cities such as Pangyo, another emerging city in the fields of biotech and IT, as well as Osong, Daegu, and Songdo. Earlier this year in May, South Korea President Jae-In Moon visited the Innovative Medicine Salon gathering in Osong as part of his Nationwide Economic Tour. During his visit in Osong, President Moon announced plans to help foster the South Korean biotech ecosystem, especially in the early stages of research and development (for those who are interested, I’ve added a more detailed history of the Innovative Medicine Salon at the end of this article).
▲ South Korea President Jae-In Moon visits the Innovative Medicine Salon in Osong (May 2019).
I participated in the July “Innovative Medicine Salon” in Pangyo, speaking alongside James Jungkue Lee, CEO of Bridge Biotherapeutics, a venture-stage biotech company that recently entered into a collaboration and global license agreement with Boehringer Ingelheim for their BBT-877 (autotaxin inhibitor for the treatment of idiopathic pulmonary fibrosis). Despite the session taking place on a weekday evening, there were over 100 life science professionals in the audience; from budding scientist-entrepreneurs to researchers, everyone in the audience shared a genuine curiosity for novel research and the global promise of South Korea’s biotech industry.
▲ LSN presented at the Innovative Medicine Salon in Pangyo (July 2019).
South Korea is a key example of the emergence and growth of biotech industries globally. With the ever-increasing surge of new therapies and technologies, the need for a global platform that can successfully connect early-stage innovations with investors and strategic partners is evident. LSN was founded in 2012 to fulfill this very purpose, when no full-fledged infrastructure for early-stage life science technologies existed.
Now could not be a better time for people to take advantage of the global ecosystem LSN has fostered, and we hope that our expansion into Asia could lead to more valuable connections that will ultimately lead to investment, licensing, and/or other win-win partnerships.
Special thanks to Sung Joo “SJ” Lee, Founder of Innovative Medicine Salon, for contributing to this article. SJ remarked that LSN and Innovative Medicine Salon have a lot of similarities – both were established in the same year and are working on growing the life science ecosystem with their own unique approaches. SJ has been inspired by LSN’s role in connecting early-stage innovations with investors and strategic partners, and hopes that LSN and Innovative Medicine Salon can continue to positively impact the life science community.
In previous years, South Korea’s bio industry was focused on the development of incrementally modified drugs (IMDs) and biosimilars. As the field of novel drug discovery and development continued to grow, so did the need for a “first mover” approach, as opposed to the existing “fast follower” strategy. The need for collaborating and interacting with various external experts, creating new ideas, and fostering open innovation became a high area of need in the industry. The “Innovative Medicine Salon” started in 2012 with a small group of researchers in Daejeon who shared this vision.
The group members gathered and listened to seminars of domestic and global experts on the theme of “innovative medicine” and debated about various topics. Their passion for innovative drug discovery and thirst for knowledge and exchange of information fueled discussions in the casual networking sessions that followed.
Information about the Innovative Medicine Salon quickly spread via word of mouth among academia, researchers, and other industry professionals. Attendance from other regions of South Korea grew, with people often trekking 2 hours or more to reach the event. It was only a matter of time before the Innovative Medicine Salon expanded to Pangyo, a city well-known for their thriving biotech and IT startup community. At Pangyo, 50 to as many as 180 attendees gathered every month, continuing the exchange of valuable opinions to everyone’s mutual benefit. Naturally, IMS fortified its position as an important support system for everyone embarking on new challenges in the field of innovative drug discovery. From thereon, Innovative Medicine Salon gatherings expanded into (1) Osong (home to the Ministry of Food and Drug Safety and other institutions dedicated to accelerating new drug development), (2) Daegu (home to the Korea Brain Research Institute and several biotech companies), and (3) Songdo (home to leading CMOs such as Samsung Biologics and Celltrion).
IMS is unique in that it is volunteer driven, independent from large institutions or corporations, which enables a more free, spontaneous academic exchange – the members who voluntarily take on operating roles include full-time biotech CEOs, professors, service providers, patent lawyers, and more.
Apart from offline meetings, the Innovative Medicine Salon operates a thriving Facebook group with over 4,000 members through which people regularly share and exchange information.
By Karen Deyo, Senior Investor Research Analyst, LSN
The panels at RESI are designed to help companies in their approach to their fundraising campaign, learning from investors what’s trending, what’s oversaturated, what to expect of the process and what red flags they should avoid. However, there is also a lot to be gained from learning from those who have been there before.
On the Tales from the Road panel, CEOs who have raised capital share their stories. These CEOs have succeeded in the fundraising process in the not-so-distant past and will share their perspective on what was absolutely crucial to their success.
Moderated by Greg Mannix, LSN’s VP of International Business Development, these five CEOs share their experiences, what worked and what didn’t, in their fundraising campaigns. Taking place from 4:00-4:50 PM at RESI Boston, come hear their stories and learn from their successes (and mistakes)!
Greg Mannix – VP at Life Science Nation (Moderator)
Greg Mannix is Vice President of International Business Development at Life Science Nation. After graduating from the University of California, he moved to Europe where he began a career in the life sciences and obtained a Master’s degree from IE Business School in Madrid. He has extensive experience in sales and marketing management in the medical devices field. He has worked extensively in Europe, North America and Latin America and he speaks English, Spanish and French. Greg’s role at LSN is to provide international early-stage companies with the tools and strategies to succesfully fundraise and to facilitate cross-boarder investments, licensing and M&A transactions.
Ilana Odess – CEO at Woven Orthopedics
Ms. Odess has spent her entire career within the healthcare & science industries and has held senior executive roles for multinational companies and start-ups such as Israel Chemicals, Johnson & Johnson, Advanced Stent Technologies, CID. As an operator, Ms. Odess is an expert in leading companies from concept to clinical application and has created multiple businesses acquired by multi-billion dollar medical device companies, negotiated over 30 worldwide partnerships, and commenced direct corporate operations in Israel for Johnson & Johnson. As an investor, Ms. Odess has led international medical technology investments and management buyouts for an international family office and led Johnson & Johnson’s acquisition of two businesses. Ms. Odess has been recognized for her ability to create successful innovative solutions and has received both a Frost & Sullivan award for innovation and the state of Connecticut’s “2014 Woman of the Year” award for Entrepreneurial Innovation and Leadership. Ms. Odess graduated with a BS in Biochemistry and an MBA from Bar-Ilan University.
Kasper Roet – CEO at Quralis
Kasper Roet is CEO and co-founder of QurAlis Corporation, is an experienced entrepeneur and worked both in industry and academia. Kasper has relevant expertise in ALS and other neuro indications. He received his PhD at the Netherlands Institute for Neuroscience working on gene therapies for paralysis. He co-founded Netfase, was BD and alliance manager at the Harvard Stem Cell Institute and fellow at the Boston Children’s Hospital. He worked at Janssen Vaccines as adjunct technical integrator and assay development lead.
Hank Wu – CDO at Luminopia
Hank Wu serves as serial entrepreneur and advisory board member in the Boston, Taipei and Jerusalem digital health communities. His startup highlights include advanced analyticsfor electronic health records, Flagship / Google-backed biotech, digital therapeutics for neuro-visual disorders and multi-sided healthcare platforms.
Previously, Hank led digital strategy and innovation at Biogen, where he worked on digital biomarkers using computer vision, machine learning and wearables; created the talent development program for digital health; and put the company on the map as thought leader at Bio-IT World and AWS:reInvent.
Hank received his left brain from the University of California, Berkeley (electrical engineering and computer science), his right brain from Johns Hopkins University (biotech) and his hindbrain from MIT Sloan. He is a co-author of peer-reviewed scientific publications and patents through his early work at the University of California, Berkeley, the J. Craig Venter Institute and the National Lab for Cancer Research.
Alejandro Zamorano – VP Business Development at PainQx
Handles all strategic and partnering opportunities for PainQx. Alejandro has 10 years of experience in business development finance, marketing, and fundraising in the life sciences. PainQx is an A.I. powered medical device company that has developed a method to objectively measure chronic pain. The PainQx platform achieves this by assessing neural activity using EEG from a patient’s brain and processing and decoding the data through proprietary algorithms. The output is a scaled pain biomarker correlates to a patient’s pain state. The PainQx platform will be used by physicians as a biomarker to gauge the dosage of medication and the efficacy of a treatment regimen. This is an especially pressing need given the opioid epidemic which in 2017 claimed 49,068 Americans. Previously Alejandro was Co-Founder & VP of Business Development at Life Science Nation (LSN), an online platform that helps entrepreneurs connect with investors that fit their investment needs. During Alejandro’s tenure at LSN, the business grew from 1 to 22 employees, opened of a broker-dealer (Boston Innovation Capital), created a quarterly conference (Redefining Early Stage Investments), and the launched the LSN Company and Investor Platform. Previous to LSN Alejandro was Business Development Executive at Abpro a CRO specializing in the development of recombinant proteins, monoclonal antibodies, and the associated assay development. Alejandro joined Abpro as a financial analyst responsible for securing funding. He was then promoted to a role in Business Development. In this role, Alejandro formed discovery and development-stage collaborations with the industry’s largest pharmaceutical companies such as Novartis, Astellas, Boehringer Ingelheim, and Abbott (Now Abbvie).
The venture capital arm of a global manufacturer of innovative materials is looking for investment opportunities that will align with their parent company’s strategy for either equity investments, partnerships, licensing or acquisition. Within the life sciences, the firm will consider medical devices, novel materials, diagnostics, instruments and tools. The firm is willing to invest globally, and will invest as early as prototype/proof-of-concept stage.
The firm is interested in medical device, diagnostic or instrument and tool companies. The firm will consider all medical devices, but, if FDA approval is required, the firm prefers the company to be in the approval process. For diagnostics, the firm will consider both diagnostic/monitoring machines, tools, instruments & novel materials for Genomics & Cell & Gene therapies. The firm is also interested in instruments or tools that can be used in the medical field or for research purposes.
The firm can lead or co-invest in equity investing, and their involvement in the company after investment will depend on the partnership.
If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.
A healthcare venture capital investment firm based in Boston, Massachusetts recently raised a healthcare IT and services fund of over $250 million. The firm generally makes investments in early stage companies targeting healthcare technology and services. The investment size will vary, depending on the opportunity. The firm typically invests in companies based in the United States though is open to companies based on a global level.
In the healthcare technology sector, the firm is actively seeking new investments in healthcare software and tech-enabled services sectors with a specific focus on payment reform, patients as consmers, healthcare analytics, healthcare infrastructure, and novel service delivery models. The firm has a specific interest in transformational technologies and services that enable value-based healthcare. The firm currently is not focused on therapeutics or traditional medical device investment opportunities, though may consider medical devices with a software/data component, such as sensors, that have either already obtained FDA clearance or are not subject to FDA regulation. The firm is indication agnostic and invests in pre-revenue to growth stage products.
The firm seeks to invest in privately held companies with a strong and experience management team. The group prefers to invest in companies with cutting-edge technologies and large market potential.
If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.
A midwest-based VC firm invests in several sectors, including health and life sciences. Within healthcare, the firm invests primarily in digital heath and digital therapeutics technologies, although they will consider medical device and diagnostics companies. In addition, the firm is also now interested in investing in cell and gene therapies and manufacturing technologies as well. The firm is highly flexible regarding investment size, and will allocate from $1-50M depending on the opportunity and stage of development, with a smaller range of $2-5M for cell and gene therapy technologies. The firm frequently invests in businesses with a significant presence in the Midwest, but will consider strong opportunities elsewhere in the US, or global companies expanding to the US.
For digital health and digital therapeutics companies, the firm will invest in all stages, from pre-revenue to companies with revenue in the tens of millions, and will tailor their investment size accordingly. The firm is fairly agnostic to the type of technology, but is less interested in provider-focused tech. While the firm will consider tech-enabled medical devices and diagnostics companies, this is a secondary interest. The firm is also now investing in pre-clinical cell and gene therapy technologies, as well as companies developing manufacturing techniques for these therapies.
The firm generally prefers to lead investments, but is more likely to co-invest in companies in the cell and gene therapy space. The firm is flexible about board representation, but is more likely to take a board seat in digital-based technology companies.
If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.
A newly launched investment fund seeks to provide seed financing in promising therapeutics to help establish proof of concept for new clinical compounds and to identify novel clinical uses for existing therapeutics. The firm’s founder has robust experience with investing in and operating biotechnology and healthcare companies, and seeks to leverage this expertise to help foster innovation. The firm’s initial size of investment will be in the range of $250K to $1M. The firm has been in active discussions with academia and corporate-funded researchers to identify promising early-stage therapeutic candidates. In addition to traditional investment approaches, the firm is interested in new company creation based on promising drug candidates. For traditional investment, the firm will prioritize companies that are based in the USA, but will seek global assets for potential in-licensing and company creation around this IP. The firm expects to invest and work with 5-10 companies across the fund.
The firm is primarily interested in small molecule therapeutics, as the cost of characterizing new biologics and cell therapies is outside of its investment scale. The firm is seeking very early-stage, pre-IND assets, and will assist with successful IND filing and completion of required studies. The firm primarily seeks therapeutics for rare diseases that qualify for orphan drug designation, but apart from that the firm is indication agnostic.
If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.