Archive | May, 2017

Finding, Vetting and Profiling Assets – LSN’s Unique Sourcing & Ranking Service (SRS)

4 May

By Dennis Ford, Founder & CEO, Life Science Nation; Creator of RESI Conference Series

Life Science Nation (LSN) has created a funding and partnering platform for early-stage life science companies in biotech, medtech, diagnostics and digital health that is unique to the industry. The platform consists of two databases, one tracks emerging life science companies and the other curates investors from around the world who are funding these entities. Augmenting these two platforms is the Redefining Early Stage Investments (RESI) Conference series and an I-Bank, Boston Innovation Capital (BIC) that help facilitate the matching up of buyers and sellers.

LSN’s unique position and range of capabilities has attracted interest from both domestic and foreign life science entities looking to leverage LSN’s global access to technology, specifically the plethora of technology assets in North America. This has resulted in various projects that utilize LSN’s infrastructure and reach into its partnering network. As a result LSN decided to offer a Sourcing and Ranking Service (SRS) that allows pharma and other buyer/licensees a way to quickly develop a complete picture of and gain access to the assets targeting a particular indication or specific technology type.

LSN’s Sourcing & Ranking Service (SRS) provides a three tier classification of assets, consisting of initial identification and aggregation of “Global Heat Maps” and “Global Target Lists” of the technologies/companies for a specific project.  We then deliver a deep-dive analysis of the select top assets that best fit the client’s objectives.  LSN has developed an expert system that powers this new capability to source, vet and stack-rank assets around virtually any life science sector. This service allows pharma groups and others looking for acquisitions or licensing deals to quickly scan the global landscape for a desired indication or technology type and dial in top contenders for investment and partnering objectives.

*   Level 1 Profile – LSN starts a client’s project by initially creating a “Global Heat Map” identifying where the assets are and then curating a ‘Global Target List” of all the companies and technologies and provide first level profile information on these companies. uncovered that are a potential fit. At the heart of LSN is a very strong and diverse research team that can efficiently gather and parse information using the LSN Company Database of 45,000 emerging biotech, medtech, diagnostic and healthcare IT companies. Which include data on financing rounds, management team and breakdown of pipeline (indication, stage of development, licensing status), the target company’s website and other informational resources are used to create a comprehensive list of relevant companies and their technologies.

*   Level 2 Profile – The Level 2 profile consists of our research team members calling all the core “global target list” entities and conducting one-on-one interviews. The researcher uses a survey that LSN has created and is the foundation of the LSN expert system. The survey conducted via a one on one phone interview which encompasses a dozen key topics that involve over 200 data elements that we accrue and enter into the expert system. The system then generates a score for each entity based on the weighted categories and the data elements within each category. The combination of the level 1 and 2 profiles provide an up-to-date, multi-layered, and actionable profile which now can be stack ranked. This stack ranking is based on the individual score generated through the expert system for each company. LSN delivers this information via reports and also allows the client access via a secure password protected content/data vault. LSN’s sourcing and ranking service allows clients to be highly selective and much more efficient from a time perspective delivering results within 90 days.

*   Level 3 Profile – LSN works with the client to select the top assets from the stack rank list that best fit the client’s objectives. Based on client’s input, LSN will conduct a more detailed assessment of these companies—building off of the initial phone conversations. LSN research will obtain all the available company collateral such as executive summaries, PowerPoint presentations, technical publications, as well as their most up to date white papers and business plan. At this point LSN collaborates with the client to design more elaborate interviews with additional one-on-one phone conversations and in-depth interviews as we build and enhance the Level 3 Profiles. The new profile allows LSN to create a new stack ranking order based on the additional data and generate a summary report for the client.

*   Data Vault – The client has access to a proprietary ‘Data Vault’ which will be hosted by LSN on a secure website to house info and portfolio of the assets discovered. The client has access to on-line ‘data vault’ with all asset information via a user name and password. The content, data and reports are never more the 90 days old.  Guaranteeing current and accurate information is critical in sourcing assets. The finalized stack-ranking report generated from LSN’s due diligence and top asset recommendations can provide a significant edge and make the client extremely efficient in evaluating technology. The Client will be able to download profiles and reports as needed.

LSN is uniquely positioned at the intersection between investors and early-stage companies. SRS is designed to provide our clients with a rapid, end-to-end research capability that will enable them to efficiently access the assets that are the right match for their new business initiatives and partnerships.

The Dynamic Landscape of Asia Outbound Dealmaking Comes to RESI

4 May

By Shaoyu Chang, MD, MPH, Director of Research & Asia Business Development Liaison, LSN

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The year 2016 saw strong outbound investments from Asia, with China leading the pack. However, the investment landscape is rapidly changing, influenced by regulatory pressure, political uncertainty, and market demand. For North American entrepreneurs seeking opportunities in Asia, it is critical to understand your counterpart’s strategy and incentives.  Therefore for RESI San Diego, LSN has introduced new panel sessions to the Asia-North America Track in order to highlight the current key players in the region.

China Healthcare Investors

China is clearly a frontrunner in outbound activities. China’s foreign direct investment (FDI) set a record of US$94.2 billion in 2016, up 189% in North America and 90% in Europe, compared to the prior year. Despite the strict currency restrictions implemented by the Chinese government by the end of 2016, this trend is generally expected to continue in the long run.

Among all sectors, healthcare will most likely see sustained growth in investments, fueled by a rapidly aging population and favorable national mandate to upgrade its healthcare industry. The Chinese healthcare sector received 18.3 billion Yuan (US$2.64 billion) in VC investment in 2016, only second to the internet sector. Healthcare VC/PE funds are mushrooming in China in recent years. With sufficient ‘dry powder’ in hand, many fund manager are looking overseas for high-quality, high-return investment targets.

China Strategic Investors

According to PwC, China’s outbound M&A value increased by 246% last year compared to 2015. An increasing number of Chinese pharmaceutical and medical device corporations are scouting around the world for valuable assets. To work with strategic investors, typically overseas partners will have to offer one or more of the following: assets fitting strategically with the Chinese partner’s existing pipeline; critical expertise such as technology platform, production knowhow, and regulatory experience; or access to key markets in the US or Europe.

Korea/Japan Investment Environment

While Chinese outbound deal making is likely to be slowed by tighter currency control, analysts expect Japan’s cash-rich firms to pick up the slack. Many Japanese pharmaceutical companies have already established multinational operations and have participated in overseas venture deals. A weak domestic consumer market and negative interest rates will further drive these corporations to expand businesses offshore.

Following years of government spending in R&D, Korea is experiencing a biotech boom. In 2016, VC investment in Korean biotech surpassed that in IT for the first time. Korean healthcare startups have attracted interest from foreign investment groups and multinational pharma companies. Fueled by the optimistic mood, Korean corporations are now actively engaged in outbound acquisition and expansion.

The week of the BIO event in San Diego sets the perfect stage for cross-border dialogues. The upcoming RESI San Diego conference will include three panels: China Healthcare Investors, China Strategic Partners, and Korea/Japan Investors. Highly experienced deal-makers are invited to share their first-hand experiences and help entrepreneurs understand the nuts and bolts of building a successful collaboration with Asia.

RESI San Diego Panel Announcement – Diagnostic Investors

4 May

By Michael Quigley, VP of Market Research, LSN

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Fundraising for diagnostics companies, like most early stage healthcare technologies, is no easy task. A relative lack of a thriving M&A/IPO exit environment compared to other life science sectors along with high profile flops in the space has made some investors wary. However there exists a significant need for advancement in the field of diagnostics. From pharma companies wanting novel biomarkers to more accurately stratify patients for clinical trials, to the rise of personalized therapies via genomic testing, there’s a growing need for more accurate diagnostics and in many disease areas they do not currently exist.

In addition, many traditionally software or technology focused VCs and major strategics are looking to utilize their expertise to advance bioinformatic breakthroughs. While some these “new” healthcare investors have learned the hard way the difference between healthcare and consumer tech, as they continue to learn they will likely represent an increase of value added capital to the space.

In this session, we will hear from 5 Investors including VCs, large corporations and angels with experience and intent to invest in early stage diagnostics companies. The speakers will cover the types of investments they are looking to make and share insights they have learned working within the space. For any entrepreneur looking to raise capital for a diagnostic technology this is a must attend panel. Look below to see the speakers for yourself. We hope to see you in San Diego.

Hot Investor Mandate 1: Oncology Fund Invests in Novel Cancer Drugs

4 May

A Europe-based firm that specializes in investing in oncology is currently investing from its third oncology fund of USD 64 million. The firm generally makes investments in Series A, B or C equity rounds; the firm is not interested in seed rounds. The firm typically makes allocations of $3-8 million, and may either lead investments or act as a co-investor alongside a syndicate. The firm is open to oncology opportunities globally but has recently invested primarily in the USA.

The firm is currently focused on oncology therapeutics. The firm will consider any form of therapeutic molecule in oncology, including small molecules, antibodies or new technologies such as cell therapies. The firm generally invests at the late preclinical stage, from 6-12 months pre-IND, but is also interested in companies with Phase I or Phase II assets.

The firm places high importance on the management team’s scientific rigor and industry experience; the firm prefers to work with entrepreneurs who have led biotech companies previously. The firm also considers the strength of the investor syndicate and their alignment of interests.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Investor Mandate 2: Southeast VC Raises New Fund for Therapeutic and Medtech Opportunities

4 May

A Venture Capital company based the southeast USA manages several funds, with its most recent fund having had its first close in 2017. The firm looks to provide up to $3-4 million of preferred equity capital in the initial round and up to $6 million over the life of the investment. The firm is very flexible in terms of period to exit but generally looks to exit in around 5 years. The firm will consider companies globally.

The firm is currently looking for companies developing Therapeutics and Medical Technology. Within therapeutics, which is the firm’s primary focus, companies with an asset anywhere from pre-clincal with positive animal data to phase II will be considered. The firm is generally open to all technology types and indications with the exception of wound care and psychiatry. Within devices, the firm is currently looking for market approved product with early revenue; however, devices are not an investment priority at present. The firm is looking for companies targeting true un-met medical needs where either no treatment currently exists or the existing standard of care is wrought with side-effects and other impediments to quality care.

The firm does not have any specific requirement for a firm’s management team although they are an active investor looking to take a seat on the company’s board. The firm generally tends to lead or co-lead investments into selected companies.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Investor Mandate 3: Hedge Fund Bets Big on Late-Stage Therapeutic and Genomic Platforms

4 May

A hedge fund sponsor with offices in New York, Hong Kong and London currently manages a total of over $30 billion in total. The firm invests primarily in public and private equity securities from a wide range of industries globally. The firm prefers to participate in a financial round of at least $40 million, and has no hard stops on phase of development. The group has the potential of allocating $100 million in equity over the life of investment in companies with at least $400 million valuation.

The firm invests across several industry sectors. In life sciences, the firm is agnostic to subsectors and therapeutic areas but is currently interested in genomics and biotech therapeutics. The firm looks for late stage platform technologies with significant market potential, and rarely invest in companies with a single therapeutic asset.

The firm is seeking competent and experienced management teams with proven business model.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Investor Mandate 4: Hematology Enterprise Invests in Medical Technology for Blood and Liver Diseases

4 May

A China-based enterprise specialized in blood purification is seeking to collaborate with early stage businesses with advanced technology and mutual cooperation on China-USA market that are a strategic fit for its pipeline and marketing resources. Equity investment size can be flexible which is mostly regarding strategic collaboration but typically ranges from US$1-5 million. The firm can also consider collaborative research, licensing, and merger and acquisition. The firm is looking for new opportunities globally with a focus on the US.

The firm is interested in consumables and medical devices in the hematology, renal diseases and liver diseases fields. The firm prefers post-prototype products with preclinical and clinical validation. Products should have a strategic angle with the firm’s pipeline.

The firm is looking for experienced management teams with sector expertise. The firm is interested in distribution rights in China.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com