RESI Boston Panel Announcement: Investing In Cell & Gene Therapy

By Lucy Parkinson, VP of Investor Research, LSN

Cell therapies and gene therapies represent the cutting edge of life science innovation.  Only a handful of treatments in this field have reached commercialization, but with many scientists forming new companies to develop treatments based on their research in this field, we could be on the cusp of a revolution in treatments for cancer, rare genetic diseases, and many other diseases.  However, startups in this field face many challenges – not the least of which is finding the right investors and strategic partners.

From among the hundreds of investors who will be attending RESI Boston, LSN has invited five experts in this field to take part in a panel discussion on how they find the right venture investment opportunities in cell and gene therapy startups, and how they guide their portfolio companies through challenges specific to cell and gene therapies, including manufacturing, regulatory issues, and more. The participants are:

Vivian Choi (Head of Gene Therapy Research, Takeda)

Strategic & scientific leader with 9+ years of gene therapy drug development experience. Spearheaded and advised at executive level on gene therapy drug development programs in 2 global bio-pharmaceutical companies. A combined 18+ years of research experience in viral gene delivery, immunology, genetics and pharmacology research. Authored and co-authored 2 US patents, 13+ scientific articles, 5+ review papers, and 20+ international conference presentations.

Elona Baum (Managing Director, DEFTA Partners)

Elona Baum is Managing Director of DEFTA Partners and has 20 years of biotech and regenerative medicine management experience. Prior to joining DEFTA Partners, Ms. Baum served as a senior executive (General Counsel & VP Business Development) for five years at the California Institute for Regenerative Medicine (“CIRM”). During her tenure, CIRM invested nearly $1 billion in regenerative medicine programs, created a $40 million iPSC bank and launched annual roundtable meetings with FDA. Prior to joining CIRM, Ms. Baum held senior positions in the legal and regulatory departments at Genentech Inc. for over a 13 year span. Ms. Baum received her BA in Economics from the University of California (Cum Laude) and her JD from the University of San Francisco School of Law (Magna Cum Laude). She served as an extern for Justice John A. Arguelles, California Supreme Court. Ms. Baum is a frequent speaker at industry conferences and is an active mentor with Enterprise Futures Network.

Kevin Scanlon (Investor, Sky Ventures)

Dr. Kevin Scanlon’s career spans roles in academic medicine, senior management in the pharmaceutical industry and biotech companies, as well as an individual investor. Currently, he is an investment advisor to Sky Ventures and a Professor of Practice at Northeastern University.

He was the Chairman of Pasadena Angels Investment Group, with ~100 investors that funded over 50 companies in two years. He has been CEO of four biotechnology companies, including Melanoma Diagnostics, which was sold to Myriad Genetics. At Schering AG/Berlex, now Bayer, he was responsible for the genomic and cancer programs.

Dr. Scanlon’s academic achievements include: Leukemia Society Scholar, Paul Martini Medical Research Prize, Co-Founder of the Nature Journal “Cancer Gene Therapy”, President of the International Society of Cell and Gene Therapy, co-authored 135 peer-reviewed scientific articles and nine medical books. Dr. Scanlon also holds seven issued US Patents.

Stefan Vitorovic (Managing Director, Vida Ventures)

Stefan Vitorovic is Co-Founder and Managing Director of Vida Ventures, a life sciences focused company-building and investment firm.

Prior to founding Vida Ventures, Stefan was an investment professional at Third Rock Ventures, an early stage life sciences venture capital firm. At Third Rock, Stefan focused on new company formation, due diligence, portfolio company financings, and partner development. He was part of the founding team of Decibel Therapeutics, a hearing-focused drug discovery and development platform company.

Before Third Rock, Stefan was an investor at TPG Capital, where he focused primarily on majority, control stakes in healthcare companies. Stefan worked on a variety of equity and debt financings, including Aptalis Pharma and Biomet. Prior to TPG, Stefan was an investment banker at Credit Suisse’s healthcare banking group. There he primarily focused on M&A and equity financings for pre-commercial life sciences companies.

Stefan received his B.S. with Honors in Biological Sciences at Stanford University. He completed his M.S. in Biology at Stanford, where he conducted biomedical research in the lab of Dr. Helen Blau at Stanford Medical School. Stefan later received his MBA from Harvard Business School. Stefan currently serves on the Board of Directors for Praxis Precision Medicines and BAIT Cellular Therapeutics and as a Board Observer for Oyster Point Therapeutics.

Yury Kukushkin (Principal, 4Bio Capital Partners)

International, trilingual venture capital professional with strong scientific background and seven years of experience inbiotech consulting and venture capital projects.

 

 

 

Hot Investor Mandate: USA Venture Capital Firm Invests in Early-Stage Device & Digital Health Technologies, in as Early as Pre-Prototype Stage Companies

A venture capital company with multiple USA offices, is currently making investments from its vintage 2019 fund and is looking to make equity investments into early stage medical devices and digital health companies. The firm’s investment size varies depending on the financial needs of the company and they generally participate in seed through series B rounds. To date the firm has only made investments in companies throughout the United States though they are open to pursuing investments globally. The firm generally makes 1-2 new investment per year.

The firm is focused entirely on early stage medical devices and digital health. The firm is open to invest in all classes of medical devices and all indications and all areas of digital health. The firm generally looks to be the first round of institutional financing often investing in companies that have yet to fully develop their prototype. Companies the firm has invested in previously include devices for Orthopedics, Diagnostics, DNA Sequencing, Women’s Health, Diabetes, Imaging, and Active and Implantable Devices.

The firm is looking for companies whose market has barriers to entry, a quick path to proof of concept, and capital efficient operations. The firm looks for passionate founders and will evaluate management on a case-by-case basis.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Hot Investor Mandate: Japanese Investment Firm Seeks Early-Stage, Breakthrough Therapeutics Including Platform Technologies as well as Diagnostics and Digital Health

A VC firm based in Japan that is opening an office in Boston, MA, invests primarily in therapeutics, with a secondary focus in molecular diagnostics and digital health. For those fields, the firm is interested in first-in-class technology approaches and will invest in early companies with great science, from seed to series A. With their expansion to the US, the firm is now open to investing globally. The firm has generally led investments, but is willing to be part of a syndicate as well. The firmI’s investments range based on the stage of the company, but will generally be no more than $5M for seed stage and no more than $10M for series A rounds.

Within therapeutics, the firm is open to both subsector and indication as long as the science is breakthrough. The firm is willing to invest earlier in platform technology companies, and will consider such technologies as early as POC stage. For companies with single assets in development, the firm prefers to see at least small animal data. For molecular diagnostics and digital health companies, the firm is opportunistic as well.

Because the firm invests early in companies with breakthrough science, they are willing to help their portfolio companies develop their strategies and operations. With its broad and trustful network with pharma companies, the firm helps portfolio companies’ boost their businesses development activities. The firm will take a board seat after investment if needed to help the company.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Hot Investor Mandate: Investment Firm Formed by Group of Chinese Medical Device Experts Invests Primarily in Early-Stage Medtech & Diagnostics Companies with China Angle

An investment group founded by Dr. Zhang Xu and six other Chinese medical device experts based in Suzhou, China seeks to allocate 5-20 Million RMB (0.7-3 Million USD) in various early stage life science opportunities. The firm seeks to make several investments in the upcoming year and focusing on opportunities raising angel,  pre-A, Series A, and B rounds. The firm seeks to make use of their founders’ expertise and successes in the medical device industry to help guide their investments towards growth and success. The firm is investing out of a CNY fund and as a result, is currently focused on companies willing to start a joint venture in China.

The firm is primarily interested in medical devices and in vitro diagnostic (IVD) technologies and/or companies. More specifically, they’re interested in opportunities in areas related to cardiology, neuromodulation, in vitro diagnostics, and imaging as that is where they have the most expertise. However, they are willing to look at other areas as well so long as the opportunity is interesting and has the potential to be developed. The firm is also interested in investing in R&D services as well. The firm’s most recent investment was in a company that utilized AI to process images in order for better and faster diagnoses.

The firm heavily prefers that the company has a China angle to work with. They believe that they can contribute more to companies who wish to work in China through connections they have already made such as through helping acquire non-dilutive funds from the government of China and utilizing various connections in industrial parks across China. The firm also wishes to work with companies that are willing to work with the partners at the firm so that they can utilize their prior experiences to help the companies grow.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Hot Investor Mandate: Venture Investment Firm Invests in USA-Based Medical Device Companies Targeting Cardiovascular & Orthopedic Indications

A venture capital firm based in USA focuses exclusively on early stage and seed investments in medical device companies. The firm provides seed, first, or second round of financing, typically in equity. The initial investment in a company ranges from $250K to $3M, with follow-on financing rounds. Accordingly, the firm invests between $2-6M over the life of an investment. The firm typically invests in companies that are based in the US, but may consider exceptional opportunities abroad. The firm is actively seeking new investment opportunities.

The firm is specifically looking for medical devices that address cardiovascular, orthopedic indications. The firm has no clinical requirements and will invest in design stage. The product must be based on strongly protected IP.

The firm prefers to invest in companies that are not looking to develop their own sales team, but rather developing a technology that can be sold at a healthy premium to a company which already has the requisite sales and marketing teams in place. The firm generally takes a board seat, but is not a requirement. In addition, the firm prefers to assume a role on the company’s scientific advisory board. The firm is looking for companies with a strong and experienced management team.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Tech Hubs in the Spotlight at RESI Boston 2019

By Bryanna Allison, Business Development Manager, LSN

We are in the age of the incubator. Sprouting up in biotech hubs such as Boston, around universities and research hospitals at a rapid rate — these facilities are intended to help entrepreneurs take those difficult first steps. With new technologies developing at an accelerated rate, it just makes sense. Starting your own company is risky, bootstrapping is even riskier. An incubator serves to soften this risk and give budding entrepreneurs some of the support and advice they need to make their company a success.

With investors and strategic partners looking earlier, either for partnerships or to keep an eye on potential future investments, it only made sense to incorporate these tech hubs into our ecosystem, creating a special segment for them at our RESI Conference in Boston last fall.

In September of 2018 LSN launched our first ever “First Coast Innovators’ Gathering” at RESI. We invited incubators, accelerators, tech transfer or regional organizations based on the East Coast from DC to Boston to not only exhibit their programs but to bring their constituents to meet with the early stage investors at RESI. These tech hubs could benefit from the exposure they receive, form relationships with investors who may be interested in their portfolio companies, while the constituents could meet potential investors or even form relationships for the future and get investor feedback on what they need to become more relevant.

To great success, LSN has incorporated a tech hub component into every conference since. RESI will be back in Boston on Sept. 11th, and joining us will be the second First Coast Innovators’ Gathering will be the following tech hubs:

 

Investors Descend on Boston for RESI

By Karen Deyo, Investor Research Analyst, LSN

We have been amazed by the enthusiastic response from investors about RESI Boston. With over 200 investors and strategic partners already registered, RESI Boston will be a great opportunity for companies, investors and service providers to network, connect and form relationships. Join us at RESI at the Westin Copley Place on Sept 11th to be a part of this global network of players in the early stage life science ecosystem!

Confirmed RESI Boston Investors

As of July 25th, 2019

And More…