Hot Life Science Investor Mandate 3: Corporate VC Arm of Healthcare Provider Seeking Early Stage Devices, Diagnostics and Healthcare IT

The corporate venture capital arm of subsidiary of a US healthcare provider has closed its third fund at $225 million in 2012.The firm makes equity investments into early-stage companies of approximately $3 million to $10 million initially with additional capital reserved for follow on financings, and generally it can invest $4 million to $15 million over a life cycle. The firm seeks to invest in companies in Series A & B financing rounds, but it is open to consider companies in other stages of development. The firm is geographically agnostic, but highly prefers to invest in companies that are based in the US.

The firm is currently looking for new opportunities in the Medical Devices, Diagnostics, Healthcare IT and Healthcare Services spaces. The firm considers all classes of medical devices and focuses on companies in the clinical stage. However, the firm will also considers products that are on the market. The firm is generally opportunistic in terms of indication.

The firm primarily invests in pre-revenue private companies. The firm looks to invest in companies with a strong management team who can demonstrate relevant experience, depth and capability to build and scale the business and attract customers Ascension Ventures typically requests a Board seat or Board observation rights for each portfolio company.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Preclinical and Phase I Investors Leading the Charge at RESI

By Michael Quigley, Director of Research, LSN

mike-2On Monday, August 18, LSN’s partnering system for our Redefining Early Stage Investments (RESI) Conference will go live. The purpose of the system is to help scientist-entrepreneurs and funding executives connect at the conference with potential investors.

Using the LSN’s partnering system is fairly straightforward. Registered scientists and executives enter information about their company’s research—including technology type, indication, and phase of development—and the system identifies registered investors who may be a fit. Then scientists and executives use the system to book meetings—as many as 16 per attendee—with those investors.

What are the interests of these investors? This conference is designed to attract investors looking to allocate to early stage companies. Exhibit 1 shows that that largest number of attending biotech investors are interested in technologies in the preclinical and phase I stages. Exhibit 2 shows that the largest number of attending medtech investors are interested in technologies that are in development and the clinical stage. Keep in mind these are just the confirmed investors are attending thus far, so expect these number to increase come September 17th.

Exhibit 1
Exhibit 1
Exhibit 2
Exhibit 2

We are able to attract a large pool of early stage investors because we target ten categories of investors. Many of these investors are relatively new to the space; a lack of capital and a glut of compelling science have attracted newcomers in recent years.

By drilling down into the data set, we are able to determine the indications of interest for registered investors. Exhibit 3 shows the number of investors interested in a given indication.

Exhibit 3
Exhibit 3

Neoplasms/Cancer/Oncology leads the pack, garnering the most interest from investors. In what may be surprising to many, diseases of the nervous system comes in at number two. This level of interest in technologies for the central nervous system is in part the result of the many specialized foundations and venture philanthropy organizations that will attend. The interest in numerous indications is another reason why this conference is of tremendous value to fundraising entrepreneurs.

Connecting with investors is only half of the value that the RESI conference offers, though. Scientists and executives also have the opportunity to attend our panels and hear representatives from all ten investor categories have in-depth discussions on a variety of topics. We hope to see you there.

Controlled Release, Nanotechnology and Structural Genomics Surfacing in the Platform Arena

By Alejandro Zamorano, VP of Business Development, LSN

Alejandro 10*10LSN Globally tracks technology platforms and has been able to yield some interesting data by classifying the different platform types and assessing the number of technologies within each classification. As you can see in Exhibit 1 LSN breaks down technology platforms into 26 categories as described below:

Exhibit1
Exhibit 1

One of the most interesting findings was that number of large molecule discovery platforms is fairly abundant in the market place. This makes sense considering the explosion of biotech companies that have emerged over the last several years each claiming their unique mechanism to creating newest and hottest molecules. In addition, the bioinformatics also seem to be a strong platform which also is in line with the advances in computational power and the increasing sophistication of software data feeds that one is able to leverage. It would appear that these technology platforms in the space that have grown to be more abundant than others as a result of a higher level of investment in their respective class at an early stage.

The bottom of the chart is perhaps the most interesting where can see technology platforms that are relatively rare in the marketplace. Controlled release platforms for example appear to be relatively novel with only 14 companies reporting an in house platform. In addition in silicon modeling (of disease physiology or mechanism of action) is also a fairly unexplored field with vast opportunity. These areas could prove highly profitable for savvy investors able to identify leading technologies in a relatively unsaturated marketplace.

Knowing where you stand relative to the marketplace is a significant data point to understand both as entrepreneur positioning yourself or as an investor making a decision.

 

 

RESI Panel Announcement: The Challenge of Outbound Fundraising

By Tom Crosby, RESI Conference Manager, LSN

Tom 2In today’s fundraising environment, investors are inundated, sometimes seeing hundreds of executive summaries a month. Life science entrepreneurs, on the other hand, are all but obligated to run a calculated outbound sales and marketing campaign. But how do you set yourself apart from the crowd? This panel features successful life science entrepreneurs at various stages of their fundraising campaigns, telling their tales from the road.

Moderated by Rick Berenson, CEO of Thermalin Diabetes, the audience will hear from:

Fred Colen, President & CEO, BeneChill

Richard Gauthier, Head of Business Development, Microbiotix

Gabor Bethlendy, CCO & Founder, Parabase Genomics

Michael Tippie, CEO, TomegaVax

Panelists will share insights and best practices based on their experiences with raising capital in the new investor landscape. The goal of the discussion is to help emerging companies understand what it takes to fund a biotech or medical device company today. What are their best tips for interfacing with different types of investors? How did they structure their campaigns? What types of resources did they use along the way, and how have they found the correct investor in the past? Listen in as these executives share their best anecdotes from tackling the challenges of fundraising first-hand.

RESI3

Hot Life Science Investor Mandate 1: Corporate VC Seeking Investments in the Intersection of Life and Materials Science

The corporate venture capital arm of a global science-based company active in health, nutrition and materials is looking The firm makes equity investments into seed and venture stage companies. The firm makes allocations ranging from a few hundred thousand dollars to $5 million initially with additional capital held for future financing rounds. The firm is looking make approximately 5-10 investments over the next 6-9 months with +10 being made over the next 2 years. The firm invests in companies located around the globe with a focus on the U.S., Europe and Israel.

The firm is looking for companies in the intersection of Life and Materials Sciences. These includes companies developing devices and materials targeting indications of cardiovascular, orthopedics, ophthalmology, dental, drug delivery and next generation cellular therapy. The firm is also interested in companies in the Agbio and nutraceutical spaces. While the firm has invested in companies all the way from seed to 3-month pre-IPO, they generally invest into companies that do not yet have a product on the market.

The firm highly values experience in a firm’s management team and generally looks to take a board seeks and play an active role in its portfolio companies. The firm is looking for companies that are in cooperation/alignment with the parent business.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Life Science Investor Mandate 2: Hedge Fund Seeking Range of Therapeutics Opportunities

A biotechnology-focused equity hedge fund based in Western US is looking to invest in therapeutics space. The investment size can vary greatly and the fund is very flexible depending on each company’s needs. The fund is geographically agnostic and looks to invest globally.

The firm is highly interested in biotech therapeutics. The fund is extremely opportunistic in terms of subsectors and indications and will consider companies at all stages of development. The fund recently invested in a European-based company developing small molecule therapeutics for CNS diseases and a US-based company developing therapeutics for oncology.

The firm seeks a company with a strong and experienced management team or technical experts in the relevant technology. The fund will require either a board seat or observer status.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com

Hot Life Science Investor Mandate 3: Global VC Seeking Therapeutics and Diagnostics with Early Human Data

A Venture Capital company with offices all around the globe is currently looking to make equity investments generally ranging from $5 to $25 million. The firm has no set number of investments it plans to make over the next 6-9 months but is actively reviewing companies for investment. The firm is willing to pursue opportunities located globally.

The firm is looking for companies in sectors of Biotechnology Therapeutics, Diagnostics, and Nutrition/Food. The firm is most interested in areas of brain health, GI (gastro intestinal), metabolic disorders and aging. The firm typically looks for early human clinical data and focused on compounds (both small molecules and biologics) with a strong safety profile that are suitable for chronic use, along with strong IP protection and a scientific rationale for their effect.

The is looking for management teams with domain expertise and a strong track record and generally looks to take a board seat following investment.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com