Pullan’s Pieces #3 – January – A Corner on Market Sentiments – Seed to Series A

29 Jul

As the saying goes, “What’s in a name? That which we call a Series A by any other name would smell as sweet.” Er… something like that, right? Hmmm, maybe it went a little bit differently.

But whatever it be, or not to be😊, the Seed Round is the new Series A. Clearly. I think we’ve all felt it for sometime but the data is in and the good ‘ole Series A just don’t buy what it used to. Nahhh… the Seed round does that, and it may buy more (equity) than it used to as a Series A (more data hunting and crunching required but one gets a sense that the venture capitalists are, well, capitalizing).

Labiotech does a really nice job collecting and summarizing a variety of topics related to financings and dealmaking in the biotech sector and the 2024 breakdown of funding offers the following approximations (roughly, with some rounding made by this author):

The internal breakdowns for amounts invested look like this:


Readers of this corner will know that we keep a close eye on the XBI

As usual, the outliers can skew the numbers (more on this in a moment) but the median amounts invested into these rounds puh-rihhhty much drive the nail in the coffin of the old thinking about Series dynamics. This data could be charted in another way in which an inverted bell curve would appear and a GAPING hole between $20M and $50M would stare back at you. Think about that for a moment… if you can’t get to value inflection for ~$15-20M, you better be raising $60-75M and have multiple reasons to do so as a cursory view of the companies listed in the dataset further indicates that the lower outliers (sub-median) on the Series A were generally geared for “finding out” about a single asset in the clinic.

Back to that previously mentioned outlier that can skew the averages… it also happens to bring even more of a spotlight to those famed words from Shakespeare which began this Corner on Market Sentiments. One of the companies in the 2024 data set raised a whopping $100,000,000 … as a Seed Round!! Indeed, a rose by any other name…

Hot Investor Mandate: VC Firm Headquartered in Asia Makes Early- to Expansion-Stage Investments Into Digital Healthcare Companies With Asia Market Potential 

29 Jul

A venture capital investor based in Asia with a presence in the US makes early- to expansion-stage investments across multiple sectors, ranging from smart cities and fintech to healthcare. Investment size is highly variable depending on the company’s stage. The firm invests alongside other venture capital firms in companies located in North America and Europe that have a market expansion strategy into Asia. 

The firm takes an opportunistic approach to digital healthcare companies, particularly those leveraging AI and bioinformatics to accelerate the drug discovery process. 

The firm seeks entrepreneurs who are passionate, driven, and enthusiastic, with sustainable business models and globally scalable ideas. 

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com

Hot Investor Mandate: Venture Arm of Investment Bank Seek Therapeutics and Medtech Companies in CNS, Oncology, and More, Focusing on US Based Opportunities

29 Jul

An investment bank headquartered in the US  does not act as a traditional investment bank, as the firm participates in venture capital, investing in and working with early-stage technology and life science companies with the main goal of taking the companies to public markets. The firm has also spun out and out-licensed technologies from universities and has capabilities to help with company formation, business strategy, IP, and early IPOs. The firm utilizes a sister company to further analyze company technologies and IPs. The firm can fund from $5-12M USD from Seed to Series A rounds with preference in US-based companies, though the firm is open to global companies. 
 
The firm is looking at biotech, medical devices, and diagnostics companies and is technology-agnostic. The firm generally does not look at digital health. There has been strong interest in immuno-oncology, neurology, and CNS. 
 

The firm works closely with companies and founders and will lead investment rounds. The firm typically requires taking a board or observer seat while deciding strategy, and once the company goes public, the firm will bring in a board member with expertise in the field. 

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com

Hot Investor Mandate: VC Firm Focuses on Global Early-Stage Medical Device Investments, With Strong Interest in Companies Developing Class III Devices

29 Jul

A venture capital firm, founded in 2019, is a global venture capital investor. The firm specializes in early-stage medical device companies and actively leverages expertise and industry resources to support portfolio companies. The firm prefers taking a leading role in investment rounds and may seek board seats in such cases. 

The firm focuses on medical devices and is open to all subsectors and indications. The firm seeks innovative technologies, primarily investing in Class III devices, and occasionally considers Class II devices if they demonstrate significant innovation. The firm is open to working with companies at all stages, including those in the early idea phase. 

The firm prefers founding teams with strong scientific expertise and comprehensive knowledge of their respective fields. 

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com

Hot Investor Mandate: USA-Based Early-Stage Venture Fund Invests in Seed Stage Companies With Opportunistic Interests Across Life Sciences

29 Jul

An early-stage venture capital firm, headquartered in the U.S., allocates roughly 40% of its investments to life sciences. The firm primarily invests from the Seed stage, with the ability to provide follow-on capital. Check sizes are flexible, typically reaching up to mid-6 figures. The firm is open to evaluating opportunities from global companies. 

The firm has broad interests in life sciences and healthcare sectors and considers all types of innovative technologies and indication/disease areas.  
 
The firm does not impose specific requirements on company structure or management teams. 

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com

Hot Investor Mandate: Investing Holding Company Backed by Leading European Institutions Seeks Europe and US-Based Companies in All Life Science Sectors 

22 Jul

An investment holding company founded by leading European institutions has raised over €100 million from a base of more than 200 institutional and private shareholders. The firm invests from Seed to Series B stages, with a strong preference for early-stage companies and potential for follow-on funding. Check sizes can reach up to $2 million per company, with flexibility based on the stage of development. The firm is open to both leading and co-investing, and while it is primarily Europe-focused, it is increasingly pursuing U.S. opportunities. 

The firm invests across biotech, MedTech (including therapeutics, medical devices, and diagnostics), and digital health. It remains modality- and indication-agnostic, seeking opportunities with strong growth potential and technological innovation. 

There are no specific requirements for company founding teams, and the firm works closely with its portfolio companies to support their development. 

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com

Hot Investor Mandate: Global Manufacturing Company Seeks Strategic Partnerships With Early-Stage Medical Device and Digital Health Companies Across the Globe  

22 Jul

A global manufacturing company, with over a century of history, is a leader in advanced materials and pressure-sensitive adhesive technologies. With a strong presence in the U.S. for many decades, it has built a reputation for innovation across industries including aerospace, electronics, healthcare, automotive, housing/construction, environmental applications, and general industry. 

In healthcare, the firm is actively seeking strategic partnerships with early-stage companies that complement its product lines. While it is open to meeting startups at the Series A stage, its focus is more on the development stage of technologies rather than funding rounds. The company has a global outlook and welcomes partnerships worldwide. 
 
The company is particularly interested in medical devices and digital health solutions. Priority technologies include sensors for applications such as injury prevention, rehabilitation for musculoskeletal disorders, stroke recovery, and neurological conditions. The company favors startups with prototypes and looks for technologies aligned with its existing products, such as flexible or stress sensors. 

If you are interested in more information about this investor and other investors tracked by LSN, please email salescore@lifesciencenation.com