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The Hero’s Journey: A CEO’s mission to find a cure to save his sons – Part II

3 Jun

Sougato-DasThe best products are often developed when the product manager is also a customer, or in the case of biotech, when the CEO is also a patient. Hear from Nick Sireau of Serenatis Bio, who developed a product that’s on the market for an ultra-rare disease, and is now preparing for a series A raise for an OCD asset after a successful seed raise. Nick’s story, including how Life Science Nation’s training, data, and events helped him, is an inspiring tale of keeping the patient first while navigating the labyrinth of the investment landscape. When Nick one day received a newsletter from Dennis Ford, CEO of LSN, saying that you need 600 – 800 investor leads to do a successful raise, he re-evaluated his strategy and realized it was a numbers game, and he had to play it fast. He searched LSN’s investor database of thousands of investors to find the best fits in the least amount of time, and participated in training from Greg Mannix, VP of International Business Development of LSN, on how to pitch and optimize partnering strategies. Now he’s on the hopeful path of bringing a treatment to a condition that is absolutely devoid of good treatment options, that can dramatically reduce quality of life and even lead to suicide. If you are an entrepreneur fundraising, this video will give you sage advice that you can use right away to accelerate your raise.

Engineering Breakthroughs: How Tecan Partners with MedTech Innovators to Scale Smarter 

3 Jun

At RESI Boston June, Tecan joins as a sponsor, and a strategic development partner for early-stage MedTech and life science companies. In this interview, Jed Palmer, Director of R&D and Engineering, shares how Tecan supports innovators from prototype to scalable product, what technologies they’re excited to partner on, and what startups can do to stand out in the eyes of a seasoned engineering team.

Jed Palmer CaitiCaitlin Dolegowski

Caitlin Dolegowski (CD): Can you briefly introduce Tecan and your role within the company, particularly as it relates to partnering and innovation?

Jed Palmer (JP): Tecan partners with companies across life sciences, diagnostics, and MedTech as an integrated, global development and manufacturing organization. Within Tecan, our Technology Development group works closely with MedTech innovators to bring breakthrough technologies from concept to working prototype in months, not years. From there, Tecan supports the transition to manufacturable, scalable solutions through our global network and operations

In my role as Director of R&D, I lead cross-functional teams of engineers and scientists who specialize in early-stage system design, particularly for electronics-based, energy-delivering and high-precision medical devices. We work closely with startups and emerging technology companies to overcome integration, prototyping, and scalability challenges, acting as a true extension of their R&D team.

CD: What motivated Tecan to sponsor and attend RESI Boston this year? What makes this conference valuable to your team?

JP: RESI Boston is one of the premier conferences that brings together a critical mass of early-stage life sciences and MedTech innovators who are actively looking for partnership, not just exposure. For us, it’s a unique opportunity to connect with founders and technical leaders who are right at that moment where concept validation meets real-world execution.

We sponsored RESI because we believe our customers’ technologies have the power to shape the future of healthcare and drive meaningful impact. As engineers, we want to be at the center of that innovation, working side by side with our partners. Our goal is to be a true strategic collaborator, not just a service provider, offering deep technical expertise and scalable platforms that help turn promising ideas into transformative, market-ready products.

CD: What types of early-stage companies or technologies are you most interested in connecting with at RESI? Are there particular therapeutic areas or platforms that align with Tecan’s strategic goals?

JP: We’re especially interested in early-stage companies developing energy-based therapies, electrophysiology tools, neuromodulation platforms, and next-gen surgical systems, particularly those integrating complex electronics or control systems. Therapeutic areas that align closely with our strategy include:

  • Cardiac and electrophysiology devices
  • Minimally invasive surgical technologies
  • Implantable and wearable therapeutics
  • Neurotech platforms

We partner with teams solving tough engineering problems in power delivery, system integration, miniaturization, etc. Our goal is to accelerate their journey to functional prototype and scale.

CD: How does Tecan typically engage with startups? Are you looking to collaborate through investment, strategic partnerships, technology licensing, or another model?

JP: Our approach is very hands-on and partnership-driven. We focus on collaborative technology development, acting as an extension of our partners’ R&D team—bringing a multidisciplinary group of engineers, physicists, and system architects to accelerate progress.

We understand that no two companies or technologies are the same. Whether it’s a short-term technical challenge or a long-term product roadmap, we work with our partners to define a structure that aligns with their goals, resources, and timelines. Our focus is on building the kind of partnership that delivers meaningful value.

CD: What advice would you give to early-stage companies looking to capture the interest of a company like Tecan at a partnering conference?

JP: The most compelling startups are the ones who are clear on what problem they’re solving—and have a grounded view of what they need help with. You don’t need to have everything figured out. What resonates with us is clarity around the application, an understanding of technical gaps, and openness to collaborative development.

Also, don’t be afraid to bring your early challenges forward. We’re not just here for polished decks—we’re here for the engineering friction points, the integration problems, and the roadblocks that need real solutions.

CD: Are there any common challenges you see when evaluating potential partners in the life science ecosystem, and how can companies better prepare to overcome them?

JP: In the early stages of technology development, it’s very common to not recognize the assumptions that were made in designing a treatment. We like to see teams that are open to having those assumptions challenged in order to progress the technology.

Another common challenge is underestimating the time and complexity required to move from proof-of-concept to a robust, testable prototype. Teams often get stuck when transitioning from feasibility to development because the architecture wasn’t built with flexibility or scale in mind.

Companies can better prepare by thinking about system-level design earlier in their process. Bringing in a development partner with deep hardware/software integration experience can help avoid costly rework, especially for energy-delivering or electronics-driven devices. Early conversations around testability, firmware strategy, and control platforms can save months.

CD: Looking ahead, what trends or innovations in the life sciences space are you particularly excited about, and how do they align with Tecan’s long-term vision?

JP: We’re particularly excited by the convergence of energy delivery technologies, real-time sensing, and closed-loop control, especially in areas like Neurostim technologies and electroceuticals. These are areas where modular, scalable architectures can unlock faster development. We’re also watching the push for personalized and distributed care, which demands smaller, smarter, and more adaptable devices.

Our long-term vision is to be the go-to partner for teams looking to innovate faster and scale smarter. RESI is one of the places where that journey starts.

Beyond Big Pharma Panel at RESI Boston June 

28 May

By Joey Wong, Director of Investor Research, Hong Kong BD, LSN

Joey-New-Headshot

At the upcoming RESI Boston conference this June, the panel Beyond Big Pharma: Partnering Early to Foster Innovation offers a rare window into how pharmaceutical companies identify, evaluate, and engage with early-stage innovators. As the healthcare industry continues to prioritize external innovation, pharma firms are increasingly scouting novel therapeutics at earlier stages than ever before. This panel brings together industry leaders who are on the front lines of these partnerships.

Panelists include:

Marc-Appel
Marc Appel

Managing Partner
Pacific Bridge NY (Moderator) 
Salma-Al-Zubi
Salma Al-Zu’bi

Investment Principal
Hikma Ventures 
Dirk-Buscher
Dirk, Büscher

Sr Director Grifols Innovation and New Technologies
Grifols
Chloe-Lepretre
Chloé Lepretre

Head of Global R&D Search and Evaluation
 Servier
Nicolas-Stalder
Nicolas Stalder

Sr. Investment Manager
Debiopharm Innovation Fund 

This panel will shed light on how pharma companies, whether the biggest players or mid-size companies, source assets, the evaluation process behind partnering decisions, and what factors drive interest at the earliest stages of development. Panelists will also share perspectives on the evolving therapeutics landscape, where unmet needs remain, and what kinds of assets are positioned to lead in the years ahead.

Whether you’re a first-time founder or a seasoned entrepreneur, this session will help demystify the strategic thinking behind pharma partnerships and provide tangible guidance for building investor interest.

RESI Boston is your gateway to strategic investors, global pharma leaders, and actionable feedback. Join us in person this June to attend this panel and over a dozen others, meet with investors through our partnering system, and experience the collision factor that defines RESI.

Meet the Finalists: 14 Sessions of Cutting-Edge Innovation at the RESI Boston June Innovator’s Pitch Challenge 

28 May

By Claire Jeong, Chief Conference Officer, Vice President of Investor Research, Asia BD, LSN

The Innovator’s Pitch Challenge (IPC) returns to RESI Boston this June with a robust lineup of 14 pitch sessions featuring early-stage companies from across the life science spectrum. Finalists span core sectors including Medical Devices, R&D, Therapeutics, Diagnostics, and Digital Health. Several sessions will highlight technologies with a specific focus—such as surgical applications, oncology, gene therapy, and advanced delivery systems—providing a deeper look at high-impact areas of healthcare innovation.

These sessions offer RESI attendees the opportunity to explore a wide range of breakthrough solutions and meet the entrepreneurs behind them. Each company will present to a panel of active investors and strategic partners, engaging in live Q&A and receiving valuable feedback. Beyond the pitch stage, IPC finalists will also be featured in the RESI exhibition hall, where they will host tables to continue conversations and meet one-on-one with potential partners and investors.

IPC voting will take place online throughout the conference, with attendees selecting their top picks. The three companies with the highest number of votes will be recognized at the conclusion of the event and featured in Life Science Nation’s Next Phase newsletter. In addition to this recognition, winners will receive complimentary registration to future RESI conferences.

More than just a pitch event, the IPC is designed to help fundraising companies gain visibility, validate their approach, and connect with a global network of partners in the early-stage life science ecosystem.

See the full list of pitching companies:

The Hero’s Journey: A CEO’s mission to find a cure to save his sons

28 May

Sougato-DasNick Sireau became a new father in 2000. However, the usual joys of parenthood were quickly cut short when Nick discovered his son had black bone disease, also known as alkaptonuria, a debilitating condition for which there was no treatment. Two years later a second son came into Nick’s life, similarly afflicted. Nick, a solar power entrepreneur, embarked on the journey of a lifetime to find a cure. Raising money any way he knew how, from half marathons to grants from the European Commission, Nick funded and led the research needed to repurpose a drug and get it approved for alkaptonuria. Click here to watch the incredible story of courage, resilience, and a refusal to give up that produced a near-perfect treatment for an ultra-rare disease that diminishes the lives of over 20,000 patients worldwide. Repurposed drugs for ultra-rare diseases rarely see the light of day due to lack of commercial incentive. Heroes like Nick, and rare disease patients everywhere, need policy-based help to provide the incentives for investors and pharmas to move more promising assets forward. At Life Science Nation, we are dedicated to connecting innovators with the capital they need to help patients. Join Nick and other heroes at Life Science Nation’s RESI conferences and become part of the solution.

BioMetas and Life Science Nation Form Global Accelerator Alliance to Transform Early-Stage Therapeutics 

20 May

By Dennis Ford, Founder & CEO, Life Science Nation (LSN)

DF-News-09142022

BioMetas Group, a leading preclinical contract research organization (CRO), and Life Science Nation (LSN), a global leader in life science commercialization and capital formation, have joined forces to launch a strategic cross-border accelerator alliance. This partnership aims to reshape how early-stage therapeutic startups are sourced, developed, and scaled, combining scientific execution with commercialization readiness to build globally fundable companies.

The new alliance links BioMetas Innovator (Singapore) and LSN Labs (Boston) into a fully integrated platform. Together, they will select and support elite early-stage therapeutic assets from their shared networks in North America, APAC, and Europe.

At the heart of the partnership is a joint service-for-equity model designed to address one of the most persistent challenges in early-stage biotechs: the capital gap between scientific promise and commercial viability. By providing critical services in exchange for equity, both accelerators aim to empower promising startups that might otherwise stall due to limited funding.

“The early-stage ecosystem often fails not because of science, but because of timing, execution, and lack of access,” said Simon Hua, Founder of BioMetas. “By partnering with LSN, we combine rigorous preclinical testing with a global commercialization platform to help these companies reach key inflection points and engage the world.”

BioMetas will deliver milestone-based development and scientific validation through its CRO services. With a team of over 150 experienced scientists and deep experience across oncology, immunology, and other diseases, BioMetas provides a full suite of preclinical services, including in vivo / in vitro pharmacology, PK/PD modeling, biomarker discovery, protein science, and IND enabling package studies. These capabilities are offered under a service-for-equity structure, allowing startups to generate high-value, decision-driving data before raising their first institutional capital.

LSN will provide its entrepreneurial education curriculum, global partnering and roadshow training, access to its proprietary investor and licensing partner database, BD Assist meeting scheduling, and the tools needed to prepare and execute global roadshow campaigns. Companies will also gain exposure by participating in the RESI global partnering conferences that connect startups with capital investors and business development teams annually at five international events.

Launching with a 20-company pilot cohort, the alliance will apply a shared diligence framework to evaluate scientific potential and commercial readiness. Participating startups will gain access to targeted development services, curated partner matching, and cross-border exposure to capital and licensing partners.

Too often, scientific founders are left to navigate commercialization alone. The new program provides a structured bridge from discovery to global market engagement, giving founders the tools, systems, and support to thrive.

“This alliance creates a new engine for global therapeutic innovation,” said Dennis Ford, Founder of Life Science Nation. “It’s not just about helping scientists become entrepreneurs — it’s about giving them the infrastructure, the partners, and the roadmap to succeed on a global stage.”

This initiative marks the first step in building a scalable venture-building infrastructure for early-stage therapeutics. As the platform expands, startups will gain access not only to services and education, but to a growing ecosystem of capital partners and strategic collaborators committed to advancing breakthrough innovation.

Media Contact:
info@lifesciencenation.com
www.lifesciencenation.com | www.biometasgroup.com

Prep for BIO & RESI with the LSN Pharma BD Directory 

20 May

Sougato-DasThe two biggest biopharma licensing and investment events, BIO and RESI, respectively, will be in Boston mid-June. BIO will feature thousands of large pharma delegates seeking licensing candidates while RESI will have over 400 seed through series B investors and pharma external innovation scouts. If you’re targeting a pharma deal in the short or long term, you should know which pharmas are best fits for you, and you should be starting conversations with them already. This applies equally if you’re seeking funding or out-licensing. Earlier stage companies will want to court the early innovation scouts at RESI while later stage biotechs will want to target the BD&L scouts at BIO.

To help you determine which pharma partners are optimally aligned with your company and submit your non-confidential deck or proposal in advance of BIO and RESI, we’ve provided the LSN Pharma Directory. This guide lists the business development/licensing/partnering pages for the top pharmas and lets you instantly see their licensing goals. Get the conversation started (for follow-up at BIO and RESI) by leveraging the submission portals contained in the Directory. The hundreds of investors attending BIO will want to see that you have a solid exit plan and have a good sense of the competitive landscape. Check out the LSN Pharma Directory for free now!

Check Out the LSN Pharma Directory for Free now!