Tag Archives: canada

Hot Investor Mandate: Hong Kong PE Firm Seeks to Invest Up to $10 M in Clinically Validated Medical Device and Diagnostics Products with China Angle

12 Jul

A PE firm that is headquartered in Hong Kong with additional offices throughout China currently manages over US$4 billion in assets and invests across several industry sectors including healthcare. The firm is interested in pre-growth and growth stage companies. Typical investment size ranges from US$5-10 million in Series A rounds. The firm seeks to lead but is open to syndicating with co-investors. The firm is now looking for opportunities in China, the US, and Canada.

Within healthcare, the firm focuses on medical devices and diagnostic technologies that have a China angle. The firm prefers products that have achieved clinical validation with proven advantages. The firm is also interested in clinical-stage biopharmaceutical opportunities as well as health information technology. The firm is opportunistic in terms of indication areas but is less interested in orphan diseases.

The firm is looking for experienced management teams with track record of success. The firm typically requests board representation in its portfolio companies.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Hot Investor Mandate 2: Canada-Based VC Partnered with China I-Bank to Invest Up to $10M or More in Life Science Companies in North America

3 May

A venture capital firm based in Canada is making investments out of its first fund which closed at $500M. The fund was jointly established with a leading Chinese investment bank. The firm usually makes initial investments in the range of $5M-$10M with additional capital reserved for follow-on investments, but is capable of making smaller or larger investments. The firm primarily makes straight equity investments, but may consider convertible notes for smaller/earlier rounds. On occasion, public companies may be considered for investment. The firm is open to opportunities globally and will lead rounds as well as co-invest in a syndicate. The firm has no set number of investments it makes per year, but is a relatively nimble firm and able to act quickly when an opportunity presents itself.

The firm’s focus is in health sciences, including therapeutics, devices, diagnostics and health IT. Generally, the firm focuses on assets with clinical data and will invest in up unto Ph. III. The firm will evaluate pre-clinical assets pending there is a strong scientific rationale, and tends to prioritize platform technologies for early-stage assets. As for medical device companies, the firm prefers to see products with clinical data.

The firm prefers to work with experienced management teams, but will consider first time entrepreneurs as well. The firm typically seeks a board seat along with investment and in addition to capital, seeks to add value through developmental, infrastructure and expertise support, as needed, through the firm’s global network. The firm’s approach is to establish long-term relationships with target companies, with a view to enable and strengthen management to realize the full potential and value of the technology.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

Hot Investor Mandate 3: Canada-Based Investment Group Provides Seed Funding to Medtech, Cleantech, and IT Sectors Across North America, With Canadian Focus

22 Mar

A venture capital fund, angel group, and registered exempt market dealer based in Toronto, Ontario is affiliated with early stage venture funds, including their accelerator fund I and II as well as an angel group. The firm usually acts a lead investor in rounds of up to $2M, with between $300K – $750K coming from the first-mentioned fund, and with additional capital usually coming from the angel group or other family offices or institutional investment partners. The firm has also participated, and will continue to participate, in larger syndicated investment rounds. The firm prefers to lead priced equity rounds and does not usually make investments in uncapped convertible debt or SAFEs (Simple Agreements for Future Equity).

Annually, the firm works with, and makes investments in, 8 to 12 early stage (Seed and Series A) companies in the IT, CleanTech and MedTech sectors. In the MedTech sector, the firm typically does not invest in products with a complex regulatory pathway. The firm is also interested in platform technologies and R&D service/tools companies. Historic MedTech investments include investments in (i) a company which has developed an imaging agent that illuminates tumors both at the surgery planning phase and inside the operating room, (ii) a company that manufactures the world’s only natural, non-toxic, mono-disperse nano particle extracted from sweet corn which has applications in the personal care/cosmetics, nutraceutical and biomedical spaces; and (iii) a company that has a proprietary in silico software platform that maps interactions of drug compounds against the human proteome to identify drug efficacy, side effects and toxicity risks.

The firm is focused on Canadian companies, but will also evaluate U.S.-based and international companies if there is a potential investment fit. The firm’s principals have significant technology, financial and legal experience. The firm’s ideal investment candidate is a company that will benefit from and can leverage this experience and network and to which the firm can provide additional long-term value beyond its cash investment. The firm tries to avoid taking on technology risk but will take on some commercialization risk and prefers entrepreneurs that have had at least one ‘win’ (or event better, at least one ‘loss’)

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

A Canadian Fundraising CEO’s Success at RESI

22 Feb

Anton Neschadim

An interview with Anton Neschadim, CEO, ImmunoBiochem
– By Chris Cummings, Senior Marketing Manager, LSN

Chris Cummings

Chris Cummings: What is your background, and how long have you been working in the life science space?

Anton Neschadim: I am a scientist-entrepreneur. I have a very deep, multi-disciplinary science background that I ultimately combined with a business degree, all from the University of Toronto. I am a lateral thinker, and as such always strived to be a subject-matter expert across multiple areas. And so, contrary to the traditional path of specialization in academia, I wanted to become a problem solver and innovator, and sought to master additional disciplines with every degree – chemistry, physics, immunology, cancer research, regenerative medicine. I believe that being able to draw on knowledge from multiple disciplines is key to generating creative insights. I transitioned into industry eight years ago, in the final year of my PhD, and took up a drug development role in a biologics program, while continuing to work in an academic lab evenings and weekends to amass more than 25 manuscripts and patents. Three years ago, I have focused on leading ImmunoBiochem with an exciting novel biologics program.

Chris Cummings: Are you currently fundraising? What previous financing or milestones has your company achieved (that you can disclose)?

Anton Neschadim: We are always fundraising, and are targeting to close another round led by current investors and partners in March. Our first deal was with one of the RESI sponsors and helped us develop fully-human antibody molecules for our lead target, and the subsequent angel-led round allowed us to develop a lead that we showed to be both efficacious and safe in preclinical animal tumor models. This new round will take our lead molecule into large animal studies, but we are eager to get into the clinic and are looking for additional capital to get us there.

Chris Cummings: How many RESI conferences have you attended previously, and when was your first event? Was ImmunoBiochem fundraising at the time?

Anton Neschadim: I have now attended three RESI conferences with the goal of raising funds every time – two in our hometown of Toronto, and the latest RESI during the JP Morgan healthcare week in San Francisco. We have closed a deal or round subsequent to each conference, and are on track to closing another round of financing following RESI in San Francisco. RESI has been extremely helpful for connecting with smart early-stage capital and learning how to better develop and tell our story to a broad range of investors. You know you have done well when you have new investors reaching out to you to learn more.

Chris Cummings: What components of RESI do you find most valuable? Do you spend most your time in partnering, or try to attend panels as well? When you participated in the Innovation Challenge, what aspects did you find beneficial?

Anton Neschadim: I tend to spend at least half of my day in one-on-one meetings, and then network with investors free-form outside of that. Panels and different tracks can help you be more targeted with the latter. I find the half-hour partnering format to be very optimal – just the right amount of time to make a connection with the investor, tell your story, answer questions, and for you to learn more about the investor’s interests and ask for feedback. The Innovation Challenge provides great exposure and is like real fundraising. It helps to have a team and to ultimately hold as many meaningful conversations as possible.

Chris Cummings: What advice can you give to other fundraising entrepreneurs attending RESI? For example, do you have any suggestions on mastering partnering, or perhaps maximizing your visibility in the Innovation Challenge?

Anton Neschadim: Visibility and being able to highlight your novelty and differentiation are paramount. What I found to be most useful is to have a team on the ground. It is great to have at least one person to move around the event, strike up conversations and bring people to your poster, while another is taking one-on-one meetings. When it comes to one-on-one meetings: register early and start requesting meetings as soon as partnering opens or even before that – spots fill up really fast. Do your research and target the right investors, avoid generic or overly long messaging, and manage time efficiently during the one-on-one meetings. The main goal is to get a second meeting or follow up.

About ImmunoBiochem

ImmunoBiochem is addressing significant unmet needs in oncology by developing highly-selective biological therapeutics. The majority of targeted biologics, which are focused on identifying and targeting unique features on the surface of cancer cells, face the challenge of tumor heterogeneity and general lack of selective tumor antigens, particularly as more potent platforms are utilized. CAR-T therapies are very exciting, with a single CAR-T cell being able to terminate from hundreds to thousands of cancer cells, but the current generation is extremely limited by very few suitable targets, such as CD19. The second generation of CAR-T therapies in the clinic will have to find a way to derive that selectivity from other mechanisms. To circumvent these challenges of surface-targeted biologics and cell therapies, ImmunoBiochem is solving this problem by combining a highly targeted and precise therapeutics platform – antibody-drug conjugates or ADCs – and non-traditional targets in the secretome of cancer cells that are amplified in the tumor microenvironment. ImmunoBiochem has defined a novel class of targets by isolating proteins with specific properties that are necessary to achieve selective and efficacious targeting of tumors with ADCs.  ImmunoBiochem was the original inventor of this technology and has tested this concept within an academic institute, and then developed a lead human antibody molecule in collaboration with the University of Toronto. Today we are supported by multiple organizations, including Johnson & Johnson Innovation (JLABS), where ImmunoBiochem is based, CCAB (the Centre for the Commercialization of Antibodies and Biologics), our key development partner and investor, OBIO, through membership and the CAAP program, and H2i at the University of Toronto.

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