By Dennis Ford, Founder & CEO, Life Science Nation; Creator of RESI Conference Series
The First Coast Innovator’s Gathering is a new component of the Redefining Early Stage Investments (RESI) Conference Series which was requested by the investors and strategic channel partners who routinely attend RESI. Many of these partners wanted LSN to bring the “earliest stage” companies so that they can identify them and get them on their radar screens in order to start a dialogue that can result in a future partnership. The First Coast Innovator’s Gathering focuses on tech hubs and companies from the First Coast of life sciences: DC, MD, PA, NJ, NY, RI, CT, and MA. Dozens of tech hubs will be attending RESI to take a spot in the exhibit hall and showcase the new technologies being developed at their institution or facility. This fall, RESI will expand to include the earliest stage companies from the discovery stage through venture stage: companies seeking grants, seed, angel, series A, and series B funding.
This RESI event offers exhibit tables to the incubators, accelerators, tech transfer offices, university translation initiatives, hospitals, research labs and their constituents, with space for incubator members’ poster boards (5 poster boards for each tech hub). LSN’s network of early-stage global investors will have access to all the key players in one place to learn about the iterative, breakthrough, and transformative technology coming out of the First Coast region.
Stetson Family Office, a Title Sponsor of RESI and a supporter of the Innovator’s Gathering, is pioneering new global funding initiatives and platforms to help the early stage players move faster through the development cycle. See below for the tech hubs that are confirmed to be part of the First Coast Innovator’s Gathering. Tech hub members are also eligible to apply for free to the First Coast Innovation Challenge to pitch in front of a panel of investors. The deadline for applications is Friday August 17th – that’s tomorrow! If you’d like to make a 7-minute pitch to investors at RESI, it’s not too late to sign up. We hope you will join us at RESI Boston on September 6th to see more. Click to see the confirmed First Coast Innovator’s Gathering participants
Incubators, accelerators, and other organizations are increasingly emerging as conduits for early stage life science companies to plug in to pre-existing networks, infrastructure, and capital. Entrepreneurs may find themselves faced with choosing whether to participate in such programs, and weigh and evaluate the benefits a given program may offer in helping them achieve their goals. At RESI on MaRS, five panelists from different groups in this sector discussed the topic from their own unique positions, each presenting the specialties and area of focus of their organization.
Gordon Kurtenbach, Senior Director of Research, Autodesk
Linda Maxwell, Founder and Managing Director, Biomedical Zone
Each model has a unique value proposition which lies in its approach to network-building
Across the board, incubators, accelerators, and other models act as hubs for connecting startups to a wide range of entities; but which entities? Christopher Kim (KSL) shared how he brings in experienced Entrepreneurs in Residence to work with management teams on their project, as well as interfacing with potential customers through his contacts in Big Pharma. Linda Maxwell elaborated on the outbound offering of Biomedical Zone, where the “focus is getting clinicians involved with the technology, to not just look at the clinical outcomes, but the business case validation.” BioMedical Zone helps companies execute pilot programs to deploy products in their partner hospitals such as St. Michael’s, where traction is gained with the people who will ultimately champion the products. Autodesk’s approach, described by Gordon Kurtenbach, is “positioning ourselves in a community, opening up our doors, and establishing a social relationship to find out what is interesting to all of us.” Dianne Carmichael said that MaRS Discovery District adds value through providing expertise and preparation to companies, as well as exposure to investors and partners – so that when entrepreneurs finally pitch to a good fit investor, they are prepared and polished. “Gone are the days when fundraising CEO’s are thrown in front of organizations that have no intention of partnering or investing in them”, she said.
Elevating the early stage ecosystem
“With incubators and accelerators, there’s somewhere in the neighborhood of 7500 of them in North America”, said Carmichael. She described how with this, there are many resources to “help companies that are starting…but I would argue that many of them don’t last.” At MaRS, a major focus is elevating the reputation of the entire early stage model ecosystem by carrying out due diligence on potential portfolio companies, and ensuring that the technology and management teams are well developed and prepared for talks with investors. Maxwell, herself an advisor to MaRS, described “working towards a new investment model, where investors are other hospitals, where we develop technology or pilot technology that people are mutually interested in.” This would result in “broadening the landscape for piloting and demonstrating clinical and business case validation.”
International collaboration is important at the earliest stages
For many companies, the “next stage” of success lies on penetrating international markets – particularly the US and Asian markets. Bringing in international investors is an excellent way to gain early exposure to global markets, competitors, and networks. For this reason, international collaboration is a key theme for firms like KSL and innovation hubs like MaRS. The relationship between people and hubs in the US and Canada are emphasized by Carmichael and Maxwell. “It’s easier to start a company in Canada than it is virtually anywhere else in the developed nations, but we have a real problem with scaling,” said Carmichael. Maxwell went on, “until we develop our own infrastructure for really adequate scaling of companies, early stage companies are going to go to the US” for that purpose.
Final Remarks
The early stage ecosystem is ripe with resources for entrepreneurs. There are a variety of models, some more hands-on than others. These will be the models that perform diligence, and bring in/coordinate with outside expertise and investors with a customized approach for their portfolio companies. Other models are more “open door”. Companies would not be expected to achieve milestones or need to wait for diligence, but should not expect the same level of guidance and support network that more rigid programs offer. Entrepreneurs should evaluate whether there is alignment between their goals and the specific “value proposition” of a given model.
It is well known that early stage therapeutic companies require a significant source of funding due to the long road of development. Despite therapeutic companies’ high-risk development timeline, many investors continue to remain focused on investing in biotechnology with a steadfast belief in the potential of the space.
For RESI on MaRS (June 23rd), LSN has assembled five highly experienced investors particularly interested in biotech therapeutics. Held in the heart of Canada’s healthcare innovation hub, MaRS Discovery District, the Early Stage Therapeutic Investors Panel will be moderated by Cynthia Lavoie, Partner of TVM Capital, and will be joined by:
Jennifer Hamilton, Senior Director, New Ventures (Canada), Johnson & Johnson
The panel will serve as an educational opportunity for scientist entrepreneurs to better understand the trends in investment in therapeutics, the investor’s perspective when approaching a deal in a high-risk space, and the best approach to initiate dialogue with them.
This is a tremendous opportunity for biotech life science entrepreneurs to meet and develop relationships with potential investors.
Incubators & Accelerators
It’s a huge challenge to launch a healthcare startup, but an increasing number of incubators and accelerator programs are stepping up to support early stage entrepreneurs and provide services, facilities and capital to speed their paths to market.
Leaders from five of these organizations are gathering at RESI on MaRS to share their experience of working with very early stage companies, and to explore how a startup can work with an incubator or accelerator partner to get ahead on their development pathway.
The moderator, Rebecca Yu, Head of JLABS @ Toronto, will be joined by:
With the explosion of activity in early stage life sciences in the last few years, many new programs have been formed to support the youngest new biotech, medtech and healthcare IT companies in developing their products and making first steps toward commercialization.
This RESI panel will highlight five programs that provide vital resources at the earliest stage, including support, work space, mentoring, business education, and investment. The panelists will talk about how they select companies, how they help entrepreneurs turn scientific ideas into commercial success stories, and what makes each of their programs unique.
Moderated by Atul Varadhachary, Managing Partner, Fannin Innovation Studio, this session will feature:
The firm is focused on therapeutics companies and does not invest in medical devices, diagnostics, or digital health. The firm is open to considering assets of very early stages, even those as early as lead optimization phase. The firm considers various modalities, including antibodies, small molecules, and cell therapy. Currently, the firm is not interested in gene therapy. Indication-wise, the firm is most interested in oncology and autoimmune diseases but has recently looked at fibrotic diseases and certain rare diseases as well.
The firm is opportunistic across all subsectors of healthcare. Within MedTech, the firm is most interested in medical devices, artificial intelligence, robotics, and mobile health. The firm is seeking post-prototype innovations that are FDA cleared or are close to receiving clearance. Within therapeutics, the firm is interested in therapeutics for large disease markets such as oncology, neurology, and metabolic diseases. The firm is open to all modalities with a special interest in immunotherapy and cell therapy.
A strategic investment firm of a large global pharmaceutical makes investments ranging from $5 million to $30 million, acting either as a sole investor or within a syndicate. The firm is open to considering therapeutic opportunities globally, but only if the company is pursuing a market opportunity in the USA and is in dialogue with the US FDA.
The firm is currently looking for new investment opportunities in enterprise software, medical devices, and the healthcare IT space. The firm will invest in 510k devices and healthcare IT companies, and it is very opportunistic in terms of indications. In the past, the firm was active in medical device companies developing dental devices, endovascular innovation devices, and women’s health devices.
A venture capital firm founded in 2005 has multiple offices throughout Asia, New York, and San Diego. The firm has closed its fifth fund in 2017 and is currently raising a sixth fund, which the firm is targeting to be the largest fund to date. The firm continues to actively seek investment opportunities across a […]