Tag Archives: LSN

Hot Investor Mandate 3: Investment Arm of Major China Genomics Company Looks for Complementary Early-Stage Genomics & Big Data/AI Technologies

15 Mar

A branch of a subsidiary of a major genomics sequencing company in China is actively seeking technologies from the US, Canada, and China that will complement what they currently have. In addition to direct investments, the firm often functions as a strategic partner that can help provide a technology platform for a startup or even integrate the new technology into their system. The firm also provides access to their large marketing team once the product is developed to help the startup during their commercialization phase. The firm is currently interested in early stage companies: usually at seed to series A and is rather flexible as to the financing terms. Additionally, the firm is willing to work through either partnerships or direct investments.

The firm is actively seeking new genomics technologies. Currently, the firm is interested in any technology within diagnostics, digital health, and medtech that has a focus on genomics. Within the diagnostics and medtech sectors, the firm is particularly interested in sequencing technologies currently, but is willing to see all early stage genomics-based technologies within these sectors. For digital health, the firm is interested in companies involved in big data and AI that already have algorithms that can utilize the large pool of genomics data that the firm currently has access to.

When investing, the firm likes to take an active role in the company and prefers taking board seats but does not require a board seat. Otherwise, the firm prefers to work with companies that the firm can work with and help develop into either a potential integration or a productive partnership.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

When Raising Capital, CEOs Should Understand the LSN Value Proposition

22 Feb

By Skylar Jacobs, Business Development Manager, LSN

As Next Phase discussed two weeks ago, the world of early stage biotech and medtech investment is far less than straightforward and CEOs often have limited resources for learning where they fit into the capital landscape. In this article, we’ll look more closely at how LSN designed the LSN Investor Platform to address this problem.

Finding and Connecting with Investors that are a Fit for Your Company

LSN has found that the biggest difficulty for fundraising executives is identifying active investors that are a fit for their stage of development and product.  When raising a seed or series A financing, most executives go straight to a few brand name VCs and angel groups in their backyard, and, mistakenly, think this is going to get the job done. The reality is that fundraising is a numbers game, and there are thousands of groups across the world that are not currently known to the fundraising team, but may be a great fit for your venture. The problem is how to efficiently identify these groups, if they are a fit and, most importantly, how to reach them.

Global Matching Platform

Through this outreach, LSN has created the LSN Investor Database, giving fundraising executives the ability to generate a global target list of investors who are a fit for their company.  Like all databases, there is a front end of the active players – which is approximately half of our total network– which includes profiles of firms in active dialogue with the LSN Research Team and profiles of firms that have enough publicly available information/contact details to be listed.  The back-end of the database contains investors that have requested that LSN match them with fundraising companies but prefer not to be listed in the front end, investors we have identified but are not currently investing, and profiles that will be moved into the front end once we have enough data to justify value. The good news is that we think we have identified about 85% of the global early stage investors.  The functionality of the LSN Investor Database allows you to easily apply filters to generate a list of firms who are a fit for your company, which usually leaves about 300-500 firms as initial targets to begin initial qualification and potential interest.

Pricing

The LSN team has conducted an analysis of hundreds of successful fundraising campaigns and has determined that, on average, a start-up company can expect to spend between $70,000 to $100,000 on their fundraising efforts.  These costs include: creating and maintaining your marketing materials and web presence, business trips, conferences, partnering road trips and other miscellaneous costs.

Campaign Component
Typical Cost
Creating and maintaining your branding, messaging, marketing collateral and web presence for a year
$25,000 – $30,000
One conference per quarter, travel and expenses
$12,000 – $20,000
1-2 week road trip per quarter, two people
$10,000 – $15,000
Global target list of investors and campaign infrastructure
$10,000 – $12,000
Legal and professional fees
$10,000 – $20,000
TOTAL
$67,000 – $97,000

The LSN Investor Platform is competitively priced at $6,995 for an annual subscription to fundraising executives.  This pricing is based upon making you, the fundraiser, more effective and efficient by dramatically increasing your access to global investors that are a fit for your company’s stage of development and product. Pricing justification is that the annual subscription costs:

  • 10% of typical fundraising campaign costs
  • Approximately $25 per targeted investor profile

The LSN Research Team has done the work for you to collect details regarding exact investment interests, typical allocation size, fund vintage, company management team requirements, past investment history, and personal contact details for Partners, Directors, and C-Level Executives at each firm – information that is rarely found in other investor profiles. The price of the LSN Investor Database includes: initial identification of our client’s global target list of 300-500 investors, a consultation on your introductory marketing materials (intro email and deck), campaign outreach advice, and email alerts including updates of investors added to the platform who are a fit for your company.  Additionally, the LSN Investor Platform includes an export function that provides startup CEOs with data that can be imported into a CRM system to manage outreach and track the progress of every investor relationship.  LSN has already integrated with SalesForce.com to make this process seamless for our clients.  In total, LSN offers a complete package for fundraising executives to ensure they have the strategy and investor targets necessary to conduct a successful capital raise.

The Redefining Early Stage Investments Conference Series

In addition to the LSN Investor Platform, the RESI Conference is another tool provided by LSN for fundraising CEOs. The RESI conference allows entrepreneurs to meet face-to-face with up to 16 relevant investors in one day and begin to develop a personal relationship with them. Subscribers of the LSN Investor Platform have a powerful tool that allows them dig into the investors’ profile prior to the meeting to understand the investors’ interests and preferences, greatly increasing the quality of an intro discussion and making the best use of their face-time. Using the LSN Investor Platform and RESI conference in parallel creates a tremendous value for any fundraising CEO in the early-stage life science space by not only providing the connections, but also by facilitating face-to-face interactions.

In Summary

LSN estimates that approximately 250 clients who read our CEO’s book, The Life Science Executive’s Fundraising Manifesto, purchased the database, and participated in the RESI Conference Series have raised upwards of 350 million dollars.  LSN’s value add to a fundraising CEO and scientist/entrepreneur is equivalent to 5 years’ work by 6 LSN research analysts, curating your Global Target List (GTL), which is at least 50% of the effort of raising capital – finding investors that are a fit for your stage of development and product.

The personal connection between the LSN research team and an investment firm allows LSN to capture and utilize a unique flow of information and provides an unmatched tool for fundraising CEOs to understand the players in their space, their nuanced preferences/strategies and a way to begin a dialogue with them. No other service or data provider comes close to the focused, high touch, relationship-oriented nature of data collection and maintenance.

An Investor Database That Works

8 Feb

By Lucy Parkinson, Director of Research, LSN

LSN created the LSN Investor Platform, which is the only early stage life science investor platform that goes across the silos of drugs, devices, diagnostics and healthcare IT. Over 600 clients have used this service, raising millions of dollars from investors located all around the globe. We’ve recently updated our video to reflect the latest generation of the cloud-based investor and strategic partnering database – take a look below!

Diagnostic Investors Share their Insights

8 Feb

By Christine A. Wu, Senior Research Analyst, LSN

chrsitine

We see a lot of innovative point-of-care diagnostics out there, but what do these opportunities truly mean to diagnostic investors? How do diagnostic companies climb the reimbursement hurdle and how will the actionable information provided by these new diagnostics change healthcare delivery? Diagnostic investors discussed these questions at LSN’s Redefining Early Stage Investments Conference in San Francisco on January 9th.

Moderated by Akhil Saklecha, Partner of Artiman Ventures, we heard from:

  • Jenny Rooke, Venture Partner, F-Prime Capital
  • Alessio Beverina, Founder & Managing Partner, Panakès Partners
  • Eric Hargarten, Investment Associate, Sandbox Industries
  • Wouter Meuleman, Director of Investments, Illumina Ventures

Last week, we summarized what we heard from the Big Pharma panel. Now what about the diagnostics side? Below are the main takeaway points.

Consider how the diagnostic would effectively disrupt the current healthcare delivery system to solve the problem. Investors are looking at the rest of the diagnostic system, how solutions are currently being delivered, and how your solution solves the workflow of delivery. Areas these investors noted as “uncapped and wide open” are concussions and head injuries, genomics, proteomics, and oncology.

“Point-of-Care” diagnostics is too crowded an area, especially when the company does not know at what point or for what care. There are many barriers to entry for point-of-care diagnostics to demonstrate usefulness in the healthcare system. How does the point-of-care diagnostic affect a clinical decision? Other oversaturated diagnostic areas are liquid biopsies, such as blood-based oncology tests, and NGS software tools.

Focus on payor-relations by continually publishing clinical evidence, especially if aiming for reimbursement. One of the large concerns for diagnostics is reimbursement. If the company can solve a significant problem for patients, but cannot demonstrate a business case for the key players in the healthcare system, adoption will be a huge issue. Particularly in the U.S. where the expectation is for third-party insurance companies to pay, it becomes imperative for diagnostic companies to perform trials and demonstrate clinical utility in practice. Investors suggest having a person on the team dedicated to publishing studies aimed at winning over payors. How many studies should you complete before getting reimbursement, you ask? “One more than you have,” quotes Eric Hargarten from Sandbox Industries.

Think more broadly than classic venture money—VCs are not your only source of capital, especially for diagnostics. Apply for non-dilutive grant money—SBIRs are a great way to progress early-stage development. Other equity, dilutive funding sources that are not exactly the classic healthcare investors also exist. These can be tech investors that are interested in the data-side of diagnostics, as well as corporate and strategic partners. Companies should also seek foundations and family offices that are perhaps more mission-driven around the problem at hand. Incubators are also a source to gain early proof-of-concept.

Final Advice for Entrepreneurs:

  1. Have a high level of clarity. This demonstrates proprietary insight of the clinical problem and will get the investors’ attention to drive further conversation. Be sure the issue you are trying to solve is explained as clear as possible.
  2. Consider the strategic alignment with the investor. Also consider the market size, particularly for payor or provider-backed venture funds.
  3. Be prepared for technical conversations. Investors are excited by great science and great technology that solves problems others are not able to solve (think diagnosing Alzheimer’s disease before any symptoms appear!). Have your technical material on hand and be prepared to go deep. That said, be sure to also know your business model and plans for regulatory reimbursement.
  4. Carefully pick your advisors, board of directors, and KOLs. Be sure they understand what you are doing and truly champion your company.
  5. Think about what your company will look like in five years, and know what it takes to get there.

 

Life Science Nation Considers RESI China

1 Feb

By Jessica Yang, Investor Research Analyst, LSN

Life Science Nation (LSN) has created a fully integrated global matching platform that allows for buyers and sellers in the early stage life science arena to find and connect with each other based on a company’s stage of development and product. An integral part of LSN’s matching platform is the Redefining Early Stage Investments (RESI) conference series that that currently is held six times a year in life science technology hubs throughout North America and Europe. RESI is a one-of-a-kind partnering event, in that the event has a 1:1 ratio of scientist/entrepreneurs to investors/strategic partners. Hundreds of investors and strategics regularly attend the RESI conference to source technology deals.

LSN has been approached over the last two years regarding bringing the RESI conference to China. The LSN Research team has done significant outreach to help establish a strong ecosystem of China-based investors who speak on our RESI panels and use RESI as a vehicle to source and vet diverse technology assets across the silos of drugs, devices and diagnostics and digital health.

You Can Help LSN Decide on RESI China

LSN currently has concerns about bringing RESI to China, and indeed to Asia. At a typical RESI event, half of the attendees are scientist-entrepreneurs who have left a major pharma/healthcare firm or a university to create their own startup company, with initial funding sourced from government grants, friends and family, or angels. These scientist-entrepreneurs then attend RESI conferences to find additional funding. The issue for LSN and RESI is to understand if China has a sufficient number of scientist-entrepreneurs in China who are starting companies independently of government, pharma or academia? Also, if the Chinese model of life science company development is different, how can RESI adapt our conference to the Chinese model and make it work? If you’re interested in seeing RESI come to China, please take this survey below to help us better understand how we can successfully bring RESI to China. We are looking for sponsors and partners to support us in this initiative.

LSN Launches RESI on MaRS Innovation Challenge with an All New Application Portal – LSN Sourcing & Ranking Expert System

25 Jan

By Samuel Rubin, Business Development Manager, LSN

After receiving some excellent feedback from past applicants, the RESI Innovation Challenge Review Team has re-tooled the online application to create a standardized and efficient Sourcing & Ranking Expert System. For years LSN has been evaluating technologies for government organizations, large pharma, and other groups using this system to vet biotech, medtech, diagnostics, and healthcare IT companies based on their science and “invest-ability”.

LSN believes the RESI Innovation Challenge application process will now be more logical and easier to navigate, streamlining the process from beginning to end. The application has now launched online. The deadline to apply for RESI on MaRS is Friday March 2nd. We look forward to reviewing all of your impressive applications!

Life Science Nation Scores A “Hat Trick” with the Third RESI in Toronto – April 10th at MaRS Discovery District

18 Jan

By Dennis Ford, Founder & CEO, Life Science Nation; Creator of RESI Conference Series

LSN is pleased to announce that RESI on MaRS is on schedule to land in Toronto April 10th, and JLABS and MaRS Discovery District will be the Title Sponsors. The big news here is that this event will be larger from an international perspective than previous RESI on MaRS events. The global early stage life science investor and partnering community has stepped up efforts to source technology assets throughout North America, and Toronto has a trove of up and coming startups across the domains of drugs, devices, diagnostics, and healthcare IT.

LSN has built a compelling group of investors and strategic partners (dubbed “the tribe”) that use the RESI conferences as a vehicle to source and vet new technologies. These investors all have a mandate to allocate capital resources in order to fill their portfolios and product pipelines and expand their global channels. LSN has already seen very strong interest from investors based in Asia, Europe and the U.S., who are vying for panel slots at the upcoming conference. RESI’s panels will feature investors from Asia-based pharma and strategics, global family offices, venture capital firms, angel syndicates, private equity, corporate venture, foundations and impact funds. The market is heating up for early stage technology, and 2018 looks like it will be a banner year for dynamic global partnerships.

Last year, RESI on MaRS hosted over 250 Canadian and international investors who participated over 900 meetings with fundraising CEOs and scientist-entrepreneurs in one day. These investors went to Toronto with mandates for investment and indeed fostered relationships that led to deals. Part of RESI on MaRS is the Innovation Challenge which will feature 30 top life science startups that has become a major draw for the investors that attend the event. The Innovation Challenge showcases these local startups on a global stage.

MaRS and JLABS will work together to showcase best-of-breed technology to the global players at this event. RESI is also part of the Toronto Health Innovation Week, which features a bevy of activity over the course of five days, leveraging the fact that RESI on MaRS will bring in the global players. Looking forward to seeing you on MaRS!

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