Tag Archives: investment

Hot Investor Mandate 2: USA Venture Fund Invests in Therapeutics and Digital Health, With Strong Interests in Small Molecule Therapies in Inflammation, Infectious, Autoimmune Diseases

31 May

A USA-based venture capital fund is currently making investments out of a $150-million-dollar fund. The firm is looking to make 15 additional investments with allocations generally in the $1-3 million range. The firm is looking to make equity investments and is open to investing in companies globally.

The firm is interested in therapeutic companies developing small molecules for inflammation, infectious and autoimmune disease and stays away from biologics, cell and gene therapy. The firm is also interested in digital health and mobile health services, AI in healthcare, B2B2C medical devices. The firm is looking for companies with some level of proof-of-concept data either in vivo or in vitro up until Phase II of clinical trials. As for digital health, the firm is looking for scalable SAAS models, novel types of healthcare delivery, point-of-care diagnostics and patient’s self-management tools.

The firm is willing to work with incomplete management teams, often working with IP that has just recently spun out of a university. The firm is willing and able to act as a lead or co-investor in financing rounds.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

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Hot Investor Mandate 4: China-Based Investment Institution Invests in Early to Growth Stage Biotech Companies with Large Market Potential in China

31 May

A professional investment institution that is based in Shanghai invests in early and growth stage companies in the field of biomedicine through its fund management company. The firm currently manages a $100 million fund. Typical equity investments range from $5 to 20 million in Angel to Series B rounds. The firm is currently seeking opportunities from China, the US and Canada.

The firm’s key areas of focus include medicine, medical devices, diagnostics, biotechnology and healthcare services. The firm is seeking products that have large market potential in China and have achieved prototype and clinical proof-of-concept. The firm is agnostic when it comes to indication areas.

The firm is looking for competent management teams with validated assets. The firm can assist with finding registration and distribution partners in China and may request regional rights on a case-by-case basis.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

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Finding Investment Opportunities At RESI: An Interview with Andy Li (Biosense Global)

17 May

Andy Li

 An interview with Andy Li, CEO & President, Biosense Global

– By Jessica Yang, Investor Research Analyst, LSN

Jessica Yang

Earlier this week, I had the pleasure of speaking with Dr. Andy Li, the founding partner of Biosense Global LLC. Andy has attended nearly every RESI event in the last 2 years. RESI is a partnering event that enables early-stage life science, MedTech and digital health companies to meet and interact with investors and strategic partners based on mutual fit. Recently, we learned that Biosense Global has invested in two companies that Andy first met at RESI.

In this interview, Andy discusses his perspectives on his RESI experiences, Biosense Global’s investments in companies attended RESI, and some suggestions for fundraising CEOs.

Jessica: To begin, please tell us a little bit about your background and your fund.

Andy: My name is Andy Li, and I am the founding partner of Biosense Global LLC. I have more than 25 years of biomedical research and biopharmaceutical industry experience with proven track records in global drug development in multiple therapeutic areas, alliance management, and business development. Currently, Biosense Global invests in early to mid-stage biopharma and Medtech projects. With our R&D facilities in China, in-licensing assets from the U.S. and Europe to China would be an important consideration.

Jessica: How many RESI conferences have you attended? What was your first impression of the RESI Conference series?

Andy: I’ve attended RESI conference six times to date, and the upcoming Boston one will be the seventh. One thing I enjoyed about attending RESI is that I think RESI attracts early-stage companies with good qualities. The companies I met in the previous RESI have solid science and great teams, and RESI allows investors and companies from around the globe to build connections easily.

Jessica: What successes have you experienced through RESI?

Andy: We’ve invested in a company focusing on immuno-oncology that I first met in RESI. The company is called PrimeVax, and this company uses a combination of the dengue fever virus and autologous dendritic cells to induce a strong immune response along with personalized tumor targeting. In addition, we’ve invested in another company call Curtana Pharmaceuticals. I met this company at a previous RESI conference, and we continued a great relationship that eventually led to an investment. Curtana is developing therapies for the treatment of brain cancer, including glioblastoma in adults and pediatric high grade glioma in children.

Jessica: In your opinion, what are the greatest strengths of RESI?

Andy: RESI is a well-organized conference, especially in its online partnering system. Compare to many conferences I’ve attended before; I think RESI has a solid platform that allows investors to have a better understanding of attending companies and book meetings easily online. Also, since Life Science Nation has great connections with many companies in your platform, I think this helps you in organizing the RESI conference, and your significant portion of company connections also help us to find ideal companies that match our investment criteria. Another thing is that I think you choose great times to hold RESI conferences, for example, you hold RESI concurrent with BIO or JPM, and this attracts investors to attend all these events at one time to reduce travel inconvenience.

Jessica: What were some aspects that differentiated the companies you’ve invested in vs. others?

Andy: Overall, I’ll look at three aspects. First and the most important one to me is whether the company’s technology is unique and innovative. Second, I’ll look at the company’s management team – I prefer a solid team with relevant experiences. Last, I think it’s also essential that the company’s investment value is reasonable.

Jessica: How can companies better prepare for an initial meeting with your group?

Andy: Sometimes, early-stage companies that founded by scientist-entrepreneurs may only focus on the technologies. I’ll suggest companies try to touch on technology, IP, commercial potential (more important for not well-known indications), competitor analysis, and fundraising plans, etc.

Jessica: Do you have any suggestions for RESI?

Andy: It would be great for you to give suggestions for attending companies to know what aspects they can cover in their presentations and slide decks. This will help increasing companies’ qualities in RESI.

About Biosense Global LLC:

BioSense Global, LLC is an NJ-based venture investment firm that was founded in 2016 and focused on bridging Eastern and Western innovations and investment opportunities. Biosense invests in early to mid-stage biopharma and medtech projects. In addition, the company has R&D operations in China. Biosense is currently looking for new opportunities globally.

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Hot Investor Mandate 3: California-Based VC Seeking to Invest in Therapeutic Technologies that Solve Problems Within Genetically Driven Diseases

17 May

A California-based firm backed by a number of well-known global funds is actively seeking investment opportunities. The firm prefers to be the first institutional investor in a company, and is typically an active, lead investor (often the sole investor). The firm typically invests in 5 opportunities per year.

The firm focuses on genetic drivers of disease, and therefore only invests in treatments for monogenic diseases or genetically-driven cancers. The firm is only interested in treatments that elicit a disease-modifying response; treatments that target symptoms of monogenic diseases are not of interest. Therapeutics must have a clearly-defined mechanism of action. The firm usually invests at the preclinical stage, up to 18 months prior to IND, but is open to later stage candidates (including clinical).

The firm focuses on individual products, not technology platforms. The firm typically houses each single asset in its own discrete subsidiary. The firm has internal expertise in medicinal chemistry, biology, and clinical trials, with personnel having significantly contributed to 30+ INDs and 10+ approved drugs. The company will often leverage internal expertise for subsidiaries, and can also assist with recruiting.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

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Hot Investor Mandate 1: Family Office Creates Investment Arm for Medical Device Companies Based in the U.S.

10 May

A family office arm specializes in investing in and operating medical device companies in which it holds a controlling interest. The firm looks to invest in early and seed stage companies with the goal of investing in 1-2 companies per year to add to its portfolio.

The firm looks to invest in medical device companies that are still in development. The firm prefers technologies subject to the FDA 510(k) pathway, but will consider PMA/combination device and therapeutics if the technology is extremely disruptive. The investors are agnostic with regards to subsector and indication. Current portfolio companies include surgical tools for cardiovascular interventions, consumer health electronics, hospital hardware and therapeutic delivery devices for multiple clinical applications.

The firm looks to invest in companies with great technology that need operational expertise to help advance the technology to market with the goal of leveraging its internal management team for execution of product development, regulatory, and commercial strategy.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

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Hot Investor Mandate 1: Toronto-Based Single Family Office Looking to Invest in Seed-Stage Medtech, Diagnostics, and Digital Health Companies

3 May

A single family office based in Toronto, Ontario has its main focus on real estate and mining, but is now looking to expand into the healthcare sector and plans to initially invest approximately $10M into seed-stage deals in the healthcare space. The firm may potentially reserve another pool of capital for additional healthcare investments in the future. The firm has flexibility with deal structures and may make either straight equity or convertible loan investments depending on the deal. In addition to capital, the group looks to add value to portfolio companies through marketing and sales expertise. The firm has no specific number of healthcare investments it’s looking to make.

Within healthcare, the firm is focused on the medtech, diagnostic and health IT space. The firm is particularly interested in newly created or accessible markets such as leveraging smart phones, big data/data mining and AI for healthcare purposes. The firm is highly interested in mobile diagnostic devices, diagnostics for the consumer market and portable lab devices. The firm will also look at more traditional FDA regulated medical devices and diagnostics on a secondary basis.

The firm seeks companies addressing specific markets, but has no set requirements for entrepreneurs/management teams other than a very focused team that is passionate about the tech and market being pursued. The firm typically seeks a board seat along with in an investment, but may not require one depending on the terms of the deal.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

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Hot Investor Mandate 2: Canada-Based VC Partnered with China I-Bank to Invest Up to $10M or More in Life Science Companies in North America

3 May

A venture capital firm based in Canada is making investments out of its first fund which closed at $500M. The fund was jointly established with a leading Chinese investment bank. The firm usually makes initial investments in the range of $5M-$10M with additional capital reserved for follow-on investments, but is capable of making smaller or larger investments. The firm primarily makes straight equity investments, but may consider convertible notes for smaller/earlier rounds. On occasion, public companies may be considered for investment. The firm is open to opportunities globally and will lead rounds as well as co-invest in a syndicate. The firm has no set number of investments it makes per year, but is a relatively nimble firm and able to act quickly when an opportunity presents itself.

The firm’s focus is in health sciences, including therapeutics, devices, diagnostics and health IT. Generally, the firm focuses on assets with clinical data and will invest in up unto Ph. III. The firm will evaluate pre-clinical assets pending there is a strong scientific rationale, and tends to prioritize platform technologies for early-stage assets. As for medical device companies, the firm prefers to see products with clinical data.

The firm prefers to work with experienced management teams, but will consider first time entrepreneurs as well. The firm typically seeks a board seat along with investment and in addition to capital, seeks to add value through developmental, infrastructure and expertise support, as needed, through the firm’s global network. The firm’s approach is to establish long-term relationships with target companies, with a view to enable and strengthen management to realize the full potential and value of the technology.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

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