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Diagnostic Investors Explore Their Strategies at RESI Boston

31 Aug

By Lucy Parkinson, Director of Research, LSN

Personalized medicine, NGS and new biomarkers promise a new age of tailored, targeted medical care. However, diagnostics is a notoriously challenging landscape for both entrepreneurs and investors. Through our research and outreach, LSN has found that many investors are still looking at diagnostic opportunities, with some focusing exclusively or primarily on the sector. At RESI Boston, we’ve gathered five experienced investors from both the venture and corporate worlds to explain what they’re looking for in the sector and how entrepreneurs can improve their odds of finding funding for their diagnostic business.

Moderated by Tom Miller, Managing Director, GreyBird Ventures, the panelists are:

  • Alex Dewinter, Director, GE Ventures
  • Wouter Meuleman, (Director of Investments, Illumina Ventures
  • Diana Saraceni, Founder & Managing Director, Panakes Partners
  • Adam Lessler, Vice President, Canepa Healthcare

In addition to these five experts, nearly a hundred investors attending RESI have an interest in diagnostic opportunities. If you’re looking for investment in this sector, sign up now.

Next Phase Interview: NCI Program Director Todd Haim Explains How RESI Boston Became A Showcase For NIH SBIR Grantees

24 Aug

For the third year in a row, the NIH has sponsored a group of grantees to be part of the RESI Boston Innovation Challenge. This week, Dennis Ford(DF) interviews Program Director Todd Haim(TH) to explore how this relationship benefits the NIH’s grantees, and how RESI stands out as a venue for these companies to present.

Dennis Ford
Founder & CEO, Life Science Nation; Creator of RESI Conference Series

Todd Haim
SBIR Program Director, National Cancer Institute

 

 

 

 

 

 

DF: What is the basic reason NIH is showcasing technology at RESI?

TH: The NIH is supporting the SBIR awardees to showcase their own technologies, and we do this at a variety of industry conferences. And the real goal from the NIH´s perspective is that we realize that we cannot support these companies forever; and that each individual company, in order to reach the patient and the market, will need a lot more funding than can be provided just through SBIR. They will need downstream partners and funders, and it is in our interest to help as much as we can to facilitate those partnerships.  RESI along with other early stage investor conferences provides a forum for our portfolio companies to interact with these parties. The conference hosts a unique set of investors and partners that are a good match for our Investor Initiatives program. This is the third year that we will be sending our companies to RESI.

DF: How many NIH-funded companies apply for the RESI Innovation Challenge and how many are selected as finalists?

TH: Over the past 3 years, over 150 companies have applied, and 60 of those have been featured as finalists. 20 at each conference.

DF: What are some key differences you see in the RESI conference compared to other conferences you attend?

TH: I would say two things stand out about RESI. One is the inclusion of Family Offices and groups that you don´t see at many other industry forums and showcases. The other benefit of RESI is the broad base in terms of technology types. Many of the other conferences we have participated in are really focused on one technology area, whether it be devices or therapeutics. RESI has individual tracks that represent devices or that represent therapeutics, which really allows us to present a greater variety of our companies there, and I think that broad focus is very helpful at this early stage.

DF: Is this type of showcasing of NIH-funded technology going to continue?

TH: We continually evaluate the outcomes of our companies’ participation in conferences like RESI to ensure the value of such events to our portfolio companies. We recently found out that CellSight Technologies, one of the companies that attended RESI as part of NCI SBIR’s Investor Initiatives, signed an agreement with Boehringer Ingelheim to partner on a clinical study using CellSight’s technology. We hope that participation in NCI SBIR’s Investor Initiatives will result in additional partnerships and investment for our portfolio companies. Should RESI participation continue to prove effective for NCI SBIR’s portfolio companies and our program continue to have sufficient funding for these efforts, we are likely to continue considering participation in RESI.

DF: Typically, we see for the Innovation Challenge participants up to 50% get funded or get involved in partnerships but we haven’t correlated that to SBIR participants specifically (though I know of around a half dozen off the top of my head that have fared quite well by participating in RESI). 

DF: Tell the readers some great stuff that is happening right now in the NIH funding domain:

TH: Sure. NCI and many of the other Institutes participate in both the Omnibus grant funding opportunity, which is available three times a year and the next receipt date is September 5th. About two thirds, if not more, of the funding for the NIH/SBIR program is actually through the Omnibus solicitation, which is an investigator initiated solicitation. You submit the application and you tell us what you’re working on; then it gets peer reviewed and we consider it from there. Then we have some of the Institutes within the Health and Human Services (HHS) including NCI, using a SBIR Contract Solicitation that goes out once a year to fund high-priority areas for each of those Institutes. The solicitation is now available and applications are due by October 20th. You can find the solicitation on NCI SBIR’s website (https://sbir.cancer.gov), as well as on https://sbir.nih.gov. I would definitely encourage all of the readers to look at both of those funding opportunity announcements with upcoming due dates and consider applying. We are here to work with potential applicants and help them understand how the program works, and how an application can be competitive.  So I encourage you to reach out to our office (ncisbir@mail.nih.gov) or to the SBIR Program Officers and Coordinators across the NIH before you apply. If you would like to speak to a Program Officer before you apply, that is definitely something we can arrange and provide guidance. Come and talk to us, we’re always interested in supporting new companies through the SBIR program and new projects.

How RESI Turned a Good Fit Into an Exclusive Collaboration

24 Aug

By Natasha Eldridge, Director of RESI Conference Series, LSN

natasha-wp-newIn the last 4 years, RESI has facilitated thousands of new connections between early stage companies and investors, and we often hear of successful partnerships and allocations that have begun at this hub of communication and dialogue. In this article, we’ll take a look at one example of a great RESI success.

An early stage therapeutics company was one of 30 companies selected to participate in a RESI Innovation Challenge, out of over 100 applicants. Prior to the event the company used the RESI Partnering software to book a meeting with an investor representing the corporate venture capital fund of a major pharma firm that was looking for assets in their field. Although the startup was a little too early in their development process to match the corporate VC’s criteria, the technology was a strong potential fit with the firm’s pipeline. The meeting went well, and the investor therefore connected the startup to the pharma company’s Business Development team. Two years later, with additional validation for the startup’s assets, they closed a significant collaboration deal with the pharma company. This is how it works in the early stage arena – by using venues like RESI to make your first early connections with major players, you can build bridges to future deals.

This startup was based in a city that’s not established as a major biotech startup hub. It’s an example of how LSN brings together buyers and sellers from all over North America, and indeed the world. Everybody is familiar with the obvious biotechnology centers like Boston and the Bay Area, but many players overlook less obvious sources of new technology. LSN not only marks these other hubs on our map, but we also develop relationships with startups in these areas via our outreach and our “Fundraising Bootcamp” educational workshops which help scientist entrepreneurs understand the details of partnering and fundraising. At the same time, the LSN Research team speaks to investment firms and large pharmaceutical companies worldwide about what kind of technology they need to see.

In this case, the LSN Research Team and Business Development Team were speaking with both the startup and the major pharma firm. Based on the relationships developed both decided to go to RESI and met through the partnering system which matched up their profiles as good fits to meet each other. That’s how we’ve seen RESI lead to so many deals over the last 4 years.

Biotech Family Offices Discuss Direct Investment at RESI Boston

24 Aug

By Lucy Parkinson, Director of Research, LSN

RESI Partnering is now open, providing attendees with the opportunity to book one on one meetings with investors.  If you log in to Partnering, you will see a wide variety of investors available to reach out to, including venture capital firms, big pharma, angels – and family offices.

RESI Boston’s Biotech Family Office sesssion features family office investors from around the world who are making direct investments into early stage drug development companies.  These firms have a variety of strategies, interests and motivations.  If you’d like to know how family office investors think about early stage drugs and what kind of technology catches their eye, this is the panel for you.

Moderated by Colin Widen (CEO, Boston Innovation Capital), the panelists are:

  • Christine Bunt (Venture Partner, 20/20 HealthCare Partners)
  • Pini Orbach (Head of Pharma, Arkin Bioventures)
  • Alex Pickett (Principal, Mediqventures)
  • Jayson Rieger (SVP of Business Development & Portfolio Management, PBM Capital)

We’ve extended the RESI discounted registration until Friday, so if you want to hear from these Biotech Family Offices now is the time to get registered.

Get Ready, RESI Partnering Opens Monday, August 21st – New Premier Partnering Plus Is On The Docket

17 Aug

By Natasha Eldridge, RESI Conference Manager, LSN

natasha-wp-new

On Monday August 21st, Partnering for RESI Boston will open and all the entrepreneurs and investors attending the event will be able to start filling out their dance cards for RESI’s one-on-one meetings.  While RESI Partnering has always been the heart of the event, RESI also offers dozens of educational panels and workshops and also an engaging venue for ad-hoc networking.

The new Premier Partnering Plus will feature deep profiles of investors and strategic players that can be used to ensure attending startups get in front of the most relevant, best-fit buy side players possible.  Below is a partial list of investors who are already signed up to take part.  These investors range from family offices to major pharma players, from local funds to international cross border investors. Entrepreneurs can meet an incredible diversity of global investors at RESI Boston and continue the dialogue 6 weeks later at RESI NYC November 15.

While all attendees can use RESI Partnering to send meeting requests to attending investors, Premier Partnering Plus registrants will have a new unique tool to vet investor fits through viewing full mandate data for each investor.  This additional service will inform entrepreneurs as to what kind of opportunities these investors are most focused on, and for the first time, will also provide entrepreneurs with access to direct contact info.  In a previous edition, we took a closer look at what Premier Partnering Plus adds to the RESI experience.  If you’re already registered and would like to talk about upgrading your registration, please contact us at resi@lifesciencenation.com.

CONFIRMED INVESTORS AND STRATEGIC PARTNERS

Pitch Deck Pitfalls – To Get Investor Meetings, Avoid These Common Errors

17 Aug

By Lucy Parkinson, Director of Research, LSN

The LSN team reviews a lot of pitch decks on behalf of our clients, and we also hear many investor responses to startup presentations. We therefore have a unique window into what catches an investor’s eye, and what makes them lose interest. In this article, we’ll take a look at some common mistakes we’ve seen recently.

 

Tell Your Story

It’s all too easy to fill a deck with information on your science and the market but not have any unifying message that brings this information together. A deck is much more likely to get you a meeting if it tells a cohesive story. What motivated you to start this company? What goal is your company working towards? How did your fellow founders get involved? The answers to these simple questions can build your deck’s story and convince an investor to take a meeting. Remember, investors allocate to people rather than to assets – they need to know what your vision is and why you believe in this company. If you do this right, the investor will begin to believe in your company too.

It’s Not A Science Presentation

We often see pitch decks that are laden with graphs, data and images from preclinical studies. Often, these decks are produced by career scientists who have much more experience in presenting at scientific conferences than in marketing a startup to investors.

It’s important to remember that the purpose of a deck is first and foremost to get an investor interested in meeting with you. Every slide should have some important information that you and the investor can then discuss in more depth if there’s an interest. So for example, your slide might briefly summarize the results of your study or state that you found a positive result, then in conversation with the investor you could share these results in more depth if the investor wanted to see them.

Remember that life science investors, even if they’re not scientific experts personally, have access to expert reviewers who will assess your scientific case in great detail if the investor is interested in your company. Neither the deck nor the meeting has to make that deep scientific case for your startup.

Don’t Forget To Talk Business

Some pitch decks devote a lot of space to demonstrating why the scientists believe that their product will successfully demonstrate safety and efficacy in humans, but reserve little space for talking about the business that the product will power. Be realistic about the investor’s motivation: return on capital. Investors will want to know that you’re looking at the competitive landscape for your product, how your product will compete with the current standard of care (or any late-stage assets that might become a new standard of care), and how many patients your product can reach.

Don’t Miss The Exit

Investors will also be focused on how/when your company might be able to exit. Show the investors some comparable companies that IPOed or were acquired recently. In our experience, early stage biotechs benefit from starting discussions with strategic partners as early as possible – how are you positioning the product to such partners to align with their pipeline needs?

Don’t Lose Focus

Early stage biotech companies are often formed around several assets, either related via an underlying platform or created by the same scientist or academic institution. Many new entrepreneurs therefore assume that investors will be interested in the breadth of their portfolio as an opportunity to get several “shots on goal”. However, our experience is that investors generally prefer to see a clear focus on 1 or at most 2 highly promising lead programs. It is useful to mention that you have other assets as well – many strong pitch decks include a ‘Pipeline’ slide that shows all the company’s assets and the stage of development that they’ve reached – but investors primarily value the company according to the development of a lead program.

If you’re interested in getting some feedback on your deck and your investor outreach campaign, we’d be happy to provide a free consultation – you can find more details here.

Need Seed Stage Device Capital? Meet the Medtech Angels at RESI Boston

17 Aug

By James Huang, Research Analyst, LSN

james-wp

With medical technology entrepreneurs facing a challenging capital landscape, angel capital remains a vital source of early stage funding in the sector.  According to studies by the Angel Resource Institute, of every angel dollar invested in the USA, nearly 20 cents goes into healthcare and life sciences.  In recognition of the importance of angel financing to early stage companies, RESI features two angel panels, and today we would like to announce our Medtech Angels panel for RESI Boston.  If you’re interested in how to pitch to an angel group, what makes a medtech opportunity suitable for angel investment, or how angels work with their portfolio companies to hit subsequent milestones and follow-on raises, this panel is for you.

LSN has brought together five highly experienced angels who have a focus on medical technology investment.  The participants are: