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Big Data, Digital Medicine, and A View of the Future at RESI X

22 Sep

By Caitlin Kramer, Research Analyst, LSN

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RESI X featured the arrival of a new panel session – Big Data in Healthcare.  If you were unable to attend, you will have another opportunity to hear insights from investors and influencers in the space at RESI SF on January 10th.

The panel, available for your viewing below, was moderated by Nicole Fisher (Founder & CEO, HHR Strategies) and featured the thoughts and experiences of:

Each discussed the unique approaches their firms take toward evaluating big data and software investment opportunities, how they partner with and shape start-up growth, and how the healthcare system landscape is (or is not) shifting to enable a realization of the big data vision.

A unique angle toward the healthcare system and policy was brought to the table by moderator Nicole Fisher, who works on Capitol Hill as a senior healthcare policy advisor, Forbes’ Contributor, and Founder and CEO of HHR Strategies.

At many points throughout the panel discussion, the conversation trended toward how data can improve healthcare delivery and outcomes. Emerging technologies blending healthcare, science, and data do not enter the same marketplace as other generalist tech software; instead they must interface with provider systems and policies in ways that are new and different from the existing therapeutic and device sectors. Morris gave an illustrative example of the “noise” created by this new relationship: he and his primary care physician ordered genetic tests, and faced with interpreting the 24 pages of results realized “neither of us are cardio-geneticists, so now what?” While the technologies advanced by new companies may provide actionable information, the health system will ultimately play a central role in their utilization and continued innovation in the space.

Entrepreneurs need to know that technology itself frequently takes a back seat to other aspects of a company. Getting blunt, de Winter shared: “The way investors think is driven by fear and greed. You want to think about how your idea specifically addresses the greed part of that equation.” Morris, an entrepreneur himself, had to transition away from his natural enthusiasm for the underlying science of a company when he began his career in venture capital. “The order of operations in the way we look at a company is market, then team, then the product, and then finally technology”, he said.

There is consensus that teams are central to accomplishing a company’s goals. Hazlehurst describes how oftentimes a company’s goal is to “translate science into software”. She goes on, “It’s a fun and challenging problem because the lifestyle and culture between the people building in these different domains is very different, and getting everyone you need working together is more than just a technical problem.” Deep and practical expertise in life sciences and software engineering are indeed vastly separate, and teams need to effectively coordinate internally and externally with strategics to formulate long-term visions.

With regard to the technology, two main aspects of big data technologies were touched upon: algorithms and data. Entrepreneurs may be surprised to learn that IP around algorithms is not a core focus of potential investors. Algorithms will change and evolve in response to higher quality or increased data. Therefore, a more important focus is access to high quality proprietary data through partnerships or through its generation as part of the platform. “We have now over 300 million individual patient records spanning 5-10 years, but that’s not enough and we still crave more”, said Pan.

Wearables, which continuously record certain metrics for individuals, inevitably enter conversations about health data. Their true utility to big data applications in healthcare is still unclear, although it is clear that in many respects they empower individuals to better understand and track their daily habits. Creating a distinction, and if necessary a distance, between digital health trends and rigorously validated data acquisition is important to avoiding hype cycles and fostering continued innovation in the field.

How we can ultimately arrive at the vision shared by entrepreneurs, investors, established companies, and individuals is explored in moderator Nicole Fisher’s recently authored whitepaper “The Digital Medicine Crystal Ball: Unlocking the Future of Real-Time, Precise, Effective, Healthcare”, published by EBD Group last month: “It is time we agree on defining and refining the meaning of digital medicine, particularly as it pertains to the toys versus the tools that will usher in a new age of healthcare. This will determine how the proper tools can lead to the most efficient and effective R&D process, strengthen the patient-physician relationship, and simultaneously enable individuals to become the CEO of their own health.1

Life Science Nation is proud to have hosted these thoughtful and influential individuals and the firms they represent, as well as the many inspiring entrepreneurs doing the heavy lifting to champion their technologies. Said Hazlehurst, “One of the beauties of investing in early stage companies is that you’re waiting for the day an entrepreneur is going to walk through your door and pitch you on something that’s really unique and disruptive.” To our life science entrepreneurs in the audience: get out there and do it. Many, like LSN, are here to help.

  1. Fisher, Nicole. The Digital Medicine Crystal Ball: Unlocking the Future of Real-Time, Precise, Effective, Healthcare. Publication. Carlsbad: EBD Group, 2016. 4.

Chapter 13: “Straight Talk About Finding, Vetting, and Closing Capital”

22 Sep

By Nono Hu, Director of Marketing, LSN

Following the overview of the fundraising process inChapter 12, we get into some of the nitty-gritty areas and explore a few common pitfalls and how to avoid them. Chapter 13 discusses the importance of getting on the road or hitting the phone to engage with relevant investors, and why it’s important to ensure that all the investor prospects you speak with are kept in context regarding the deal. Finally, the chapter explores how to prioritize your prospects to use your runway time most effectively while raising money.

Click here to download/print the chapter PDF

Next week, LSN will bring you the final chapter, “Thirty-One Tips For Effective Fundraising”.

Enjoyed the preview? Buy now from Amazon.com or Barnes & Noble

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RESI SF 2017 Will Definitely Sell Out! Register Early Bird

15 Sep

By Dennis Ford, Founder & CEO, LSN

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After the huge success of RESI Boston, which attracted over 700 attendees for an unprecedented number of face to face meetings, it’s time to look ahead to this winter’s conference season. RESI will be joining the JPM fray for our largest event yet. The 11th Redefining Early Stage Investments (RESI) Conference will take place on January 10th in San Francisco.

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2016 has seen a grand RESI tour, beginning with a sellout event in San Francisco, then to Houston, and up to Toronto for our first international RESI event, and home to Boston in the fall. For 2017 we’ll once again open the year with a splash in San Francisco. With other events focusing on late stage or publicly traded companies, RESI San Francisco will offer early stage companies and investors an opportunity to get the most out of the wild week when the biotech and medtech world gathers by the Bay. As RESI SF is highly likely to hit capacity again, we encourage you to register early.

RESI is a venue for entrepreneurs to meet with 10 categories of investors that LSN tracks including Family Offices, Corporate Venture Funds, Angel Groups, Venture Philanthropy, Venture Capital and more. Through the RESI Partnering, fundraising executives can have up to 16 scheduled meetings as well as many more ad-hoc meetings with diverse life science investors who fit their company’s technology sector, indication and stage of development. Additionally, through an expansive series of panels and workshops, attendees will have the chance to hear firsthand accounts from investors explaining their current investment mandates and process for identifying and qualifying candidates.

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LSN Summer Reading Series Chapter 12: “Anatomy of an Allocation Process”

15 Sep

By Nono Hu, Director of Marketing, LSN

In recent weeks we’ve covered how to make a global target list of potential investors, and the basic techniques of phone canvassing and email outreach required to initiate dialogue. This week, LSN takes a look under the hood of the investment process. How do you turn that initial spark of interest into an allocation check?

This chapter explains how you can move the process forward through the pipeline and describes the people you’ll have to work with in order to make the allocation happen—from the initial gatekeepers to the final decision-makers. We look at how to make a good first impression and how to run a productive meeting with an investor, and explore what will happen during the due diligence process. If you’re preparing to meet with a potential investor in the near future, this chapter will be invaluable.

Click here to download/print the chapter PDF

Next week, join us for Chapter 13: “Straight Talk About Finding, Vetting, and Closing Capital.”

Enjoyed the preview? Buy now from Amazon.com or Barnes & Noble

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Redefining Early Stage Investments Conference Series – Boston 2016 Program Guide Announced

8 Sep

By Nono Hu, Director of Marketing, LSN

Next week, RESI is heading home for the 10th conference in Boston, where the LSN team hosted the very first RESI three years ago. So far, we have over 900 meetings booked through the RESI Partnering Platform, and have registered nearly 250 early stage investors.

LSN would like to present the RESI Boston 2016 Program Guide. If you’re planning your day in Boston and want to see full lists of the speakers, RESI Innovation Challenge participants, exhibitors and sponsors you could meet, look no further!

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RESI Boston 2016 Agenda Announced

1 Sep

By Michael Quigley, VP of Market Research, LSN

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LSN’s, Redefining Early Stage Investments conference series, is back in Boston for its 10th conference. The RESI team has produced a content rich agenda featuring over 75 investors on 18 different panels, and 5 educational workshop sessions. Investors from family offices, top tier VC’s, large pharma/medical technology firms, angels will be shedding light regarding their process of making investment decisions and what early stage companies should be doing to stand out from the crowd.

RESI Boston also represents an amazing geographic diversity with investors hailing from North America, Europe and Asia all with a common goal of sourcing early stage assets. There will be a new Asia-North America Investor Track that will feature a total of 15 different speakers representing Japan, Korea and China based firms looking to make investments across the pacific. The broad strategy of these Asian based investors is simple – identify compelling assets for their dynamic markets.

The agenda below represents the current early-stage healthcare investment landscape and how it has adapted to serve this evolving industry. Click on any image below to see the full speaker lineup for yourself and to decide who you will be listening to come September 13th.

Track 1: Therapeutics Investor Panels Track 2: Device, Diagnostic, and HCIT Investor Panels Track 3: Early Stage Workshops
Track 1: Therapeutics Investor Panels Track 2: Device, Diagnostic, and HCIT Investor Panels Track 4: Asia-North America Panels

Partnership Building: First Step of a Successful Asia Strategy for Your Startup

25 Aug

By Shaoyu Chang, MD, MPH, Senior Research Manager & Asia Business Development Liaison, LSN

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The momentum of cross-border investment from Asian countries such as China, Japan, and Korea continues to grow. China has picked up steam in overseas M&A with $122.57 billion in deal value in just the first half of 2016, shattering its record and surpassing that of the US and Germany.

The LSN team regularly travels to major innovation hubs in North America, from Boston and San Francisco to Houston and Toronto. Everywhere we go, we are seeing a growing number of Asian investors and corporations in search of innovative healthcare products. The healthcare sector has become increasingly attractive for its long-term growth as well as solutions to the buyer’s domestic unmet medical needs.

The cross-border investment scene not only has seen quantitative changes, but qualitative ones. A decade ago, only a small number of state-owned entities or large corporations went outbound to acquire strategic resources. In recent years, the arena has been filled by publicly traded or private-owned companies . The changing landscape reflects a new mindset that views overseas activities as a part of regular business strategy.

As the diversity of buyers increases, so does the scope of their investment. Backed by highly trained workforce and ‘returnee’ scientists, Asian biopharma industry has demonstrated strong ambition in innovation. Instead of focusing on snatching mature businesses, Asian biopharma companies are now active in swapping assets with their US and West European counterparts. According to LSN Licensing Deals Platform, Asia accounts for 40 percent of all global cross-border biopharma licensing deals from January to August this year (see Figure 1).

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What does it all mean for early-stage entrepreneurs? For US- and Europe-based businesses, Asia may present as a potential funding source. However, effective collaboration would never happen if you do not have thorough understanding of how your product fits into a different patient population, healthcare environment, distribution channels, and regulatory system.

Though stories of cultural clash are sometimes heard, one cannot deny that a trustworthy and experienced Asia partner can be of great help with navigating the uncharted waters and avoiding unforeseeable pitfalls. To build any business relationship, physical interaction is a critical first step, which is especially true in the Asian business cultures. For entrepreneurs with an Asia strategy, they should strive to grab every chance to get in-person time with potential Asia partners.

RESI Boston conference is offering such an opportunity, where a group of highly reputable investors and corporations from China, Hong Kong, Taiwan, Japan, and Korea are attending. Entrepreneurs working on novel therapeutics, medical devices, diagnostics or other healthcare technology will be able to find investors in your sector and engage in dialogue with them. You can find speakers on RESI Asia panels through the following links:

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