Tag Archives: San Francisco

Hot Investor Mandate 3: San Francisco-based Large Global Private Investment Firm Seeking Early-Stage Therapeutics and Commercial-Stage Devices Worldwide

10 May

A large PE/VC is investing in life science innovation through its $5B Growth and Rise funds. The firm is a leading global private investment firm with over $59 billion AUM, based in San Francisco, California. The investment size typically ranges from $20M to $50M in equity. The firm is agnostic to company location or stage.

The firm aims to invest in therapeutics, commercial stage medical devices, and opportunistically in other innovative life sciences spaces. For therapeutics, the firm seeks small molecules and biologics and is open to all indications including orphan indications. The firm will consider products in all phases of clinical trials, from pre-clinical to phase III, and also commercial stage therapeutics. The firm is open to both PMA and 510K devices, as long as the device is already being sold at a commercial stage. The firm is also interested in services such as CROs and CMOs as well as tools of genomics and proteomics.

The firm invests for the long term, and is heavily involved in, and committed to, the growth and success of their portfolio companies. The firm, therefore, generally take a board seat/observer rights. The firm only invests in private companies.

If you are interested in more information about this investor and other investors tracked by LSN, please email mandates@lifesciencenation.com.

RESI San Francisco Innovation Challenge – Check Out the Winners

11 Jan

By Nono Hu, Director of Marketing, LSN

RESI San Francisco 2018 was the biggest Redefining Early Stage Investments event yet. In a highly competitive RESI Innovation Challenge we saw novel technologies represented from the therapeutics, medtech, diagnostics, and healthcare IT verticals – we know it was tough for RESI attendees to choose how to allocate their 5 RESI “investment” tokens! We wish all our finalists the best in bringing their products forward toward commercialization, but there could only be 3 top prize winners.

First Place: CorInnova

With a $6 million lead investment from the UK-based Wellcome Trust ($26 billion in assets), CorInnova is developing an innovative minimally invasive cardiac assist device to treat heart failure. The collapsible soft robotic direct cardiac compression device, deployed minimally invasively into the pericardial space around the heart, does not touch the blood. The device should reduce hospital length of stay from 30 to 4 days and adverse events vs. LVADS by 40%. It will expand the eligible patient population 3 to 4X to an addressable market of up to $14 billion. CorInnova has a world-class team. First-in-human trials are anticipated to begin in 18 months. Three similar cardiac companies with only 10 patients’ data sold for $250 to $400 million in cash.

Boris Leschinsky, Vice President of Product Development,CorInnova | Dennis Ford, CEO, Life Science Nation | William Altman, CEO, CorInnova | Keith Svagerko, Vice President, Business Development, CorInnova

 

Second Place: ImmunoBiochem Corporation

ImmunoBiochem is a privately held biopharmaceutical company solving the problem of tumor heterogeneity by targeting unique proteins enriched in the secretomes of cancer cells with Antibody Drug Conjugates (ADCs) – a promising class of biological anticancer therapeutics. ImmunoBiochem has identified a class of molecular targets that are secreted by cancer cells, but not healthy cells, and possess unique properties enabling the highly-selective delivery of toxic payloads to cancer cells, while leaving normal cells unharmed. ImmunoBiochem’s next-generation biologics aim to offer a superior safety profile and broad therapeutic window. Lead candidate, IMB-212, is aimed at a well-characterized cancer biomarker supported by a wealth of clinical data, and is being developed for Triple-Negative Breast Cancer (TNBC) – an aggressive disease for which no targeted biologics treatment options are available.

Dennis Ford, CEO, Life Science Nation | Anton Neschadim, CEO, ImmunoBiochem | Lucy Parkinson, Director of Investor Research, LSN

 

Third Place: Biorez

Biorez is an early-stage regenerative medicine company developing a bioresorbable scaffold for ACL reconstruction. Despite over 400,000 procedures each year, current surgical options are limited to autograft tissue, which requires a patient to sacrifice their own tendon, or allograft tissue, which is harvested from cadavers and has a higher failure rate. There is a large, unmet clinical need for a consistent, off-the-shelf device for ligament regeneration. The Biorez device provides the necessary strength to support physical activity, while its highly porous, proprietary structure facilitates a patient’s own cells to follow the scaffold and regenerate new functional tissue. The company is supported by early-stage VC investors, world-class scientific advisors, and a dedicated team to commercialize this exciting technology.

Dennis Ford, CEO, Life Science Nation | Kevin Rocco, CEO, Biorez | Lucy Parkinson, Director of Investor Research, LSN

Thank you to all who competed in the RESI JPM Innovation Challenge, and to all the RESI attendees who took part by investing their votes in their favorite competing companies. Welcome to join our upcoming RESI on MaRS event on April 10th, register now.

Meet The RESI San Francisco Innovation Challenge Finalists

21 Dec

By Chris Cummings, Senior Marketing Manager, LSN

Happy Holidays! With just under 3 weeks until the 4th annual RESI San Francisco, LSN is proud to announce this year’s crop of innovative new life science companies participating in the RESI Innovation Challenge.

The RESI Innovation Challenge covers startups in therapeutics, medtech, diagnostics and healthcare IT companies from around the globe. All applicants are vetted based on not only the quality of the company’s scientific work, but also the strength of the management team and how well-positioned the company is to receive investment.

Previous Innovation Challenge participants have proven to be successful entrepreneurs; we have seen as many as 50% of companies in a Challenge receive funding within one year of the conference. Top competitors are able to find a balance between utilizing both the structure of RESI’s partnering system, and the ad-hoc nature of the Innovation Challenge.

On January 9th, RESI SF’s estimated 1000 attendees will receive “RESI Cash” to allocate to the entrepreneurs whose technologies they expect will be most influential. The capital invested will be tallied up and the top three winners will receive prizes and be featured in our RESI newsletter recap that will go out to LSN’s 20,000 newsletter readership.

Therapeutic

Medtech Device

Diagnostic

Healthcare IT

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