Partnership Building: First Step of a Successful Asia Strategy for Your Startup

By Shaoyu Chang, MD, MPH, Senior Research Manager & Asia Business Development Liaison, LSN

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The momentum of cross-border investment from Asian countries such as China, Japan, and Korea continues to grow. China has picked up steam in overseas M&A with $122.57 billion in deal value in just the first half of 2016, shattering its record and surpassing that of the US and Germany.

The LSN team regularly travels to major innovation hubs in North America, from Boston and San Francisco to Houston and Toronto. Everywhere we go, we are seeing a growing number of Asian investors and corporations in search of innovative healthcare products. The healthcare sector has become increasingly attractive for its long-term growth as well as solutions to the buyer’s domestic unmet medical needs.

The cross-border investment scene not only has seen quantitative changes, but qualitative ones. A decade ago, only a small number of state-owned entities or large corporations went outbound to acquire strategic resources. In recent years, the arena has been filled by publicly traded or private-owned companies . The changing landscape reflects a new mindset that views overseas activities as a part of regular business strategy.

As the diversity of buyers increases, so does the scope of their investment. Backed by highly trained workforce and ‘returnee’ scientists, Asian biopharma industry has demonstrated strong ambition in innovation. Instead of focusing on snatching mature businesses, Asian biopharma companies are now active in swapping assets with their US and West European counterparts. According to LSN Licensing Deals Platform, Asia accounts for 40 percent of all global cross-border biopharma licensing deals from January to August this year (see Figure 1).

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What does it all mean for early-stage entrepreneurs? For US- and Europe-based businesses, Asia may present as a potential funding source. However, effective collaboration would never happen if you do not have thorough understanding of how your product fits into a different patient population, healthcare environment, distribution channels, and regulatory system.

Though stories of cultural clash are sometimes heard, one cannot deny that a trustworthy and experienced Asia partner can be of great help with navigating the uncharted waters and avoiding unforeseeable pitfalls. To build any business relationship, physical interaction is a critical first step, which is especially true in the Asian business cultures. For entrepreneurs with an Asia strategy, they should strive to grab every chance to get in-person time with potential Asia partners.

RESI Boston conference is offering such an opportunity, where a group of highly reputable investors and corporations from China, Hong Kong, Taiwan, Japan, and Korea are attending. Entrepreneurs working on novel therapeutics, medical devices, diagnostics or other healthcare technology will be able to find investors in your sector and engage in dialogue with them. You can find speakers on RESI Asia panels through the following links:

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Digital Health: Two Panels Showcase the New Innovation Frontier at RESI X

By Lucy Parkinson, Director of Research, LSN

Boston is known for being the hub of the biotech world. But as software is eating the world, innovators are finding new avenues for digitization of healthcare. Some are tackling inefficiencies and bottlenecks in the healthcare delivery system; others are using big data algorithms to explore biological processes, make new discoveries, or find new signals in population health data.

RESI Boston will feature two panels that explore this collision between software and health. The Healthcare IT session will look at the current landscape in digital health investment. What kind of solutions are investors excited about, and how do they assess startups in this increasingly crowded sector?

Moderated by Michael A. Greeley, General Partner, Flare Capital Partners, the panelists are:

In Big Data in Healthcare, RESI will take a laser focused look at the new possibilities that data science is creating in biotech and health innovation. Five investors will explore what they’re looking for in a big data opportunity. The participants will be:

If you’d like to catch these panels in person, you can register for RESI now.

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LSN Summer Reading Series Chapter 11: “Email Campaigns”

By Nono Hu, Director of Marketing, LSN

This week, the LSN Summer Reading Series covers one of the most powerful tools in your fundraising arsenal: the outreach email.

From basics like mail merging and segmenting your list to sophisticated tools such as delivery scheduling and analytical tracking, this chapter covers how to use email to introduce your company to an audience of potential investors. This chapter also explains the importance of targeting the right contacts when you send an email and of including clickable links in order to uncover which recipients are engaging with your message.

Click here to download/print the chapter PDF

We hope you find this chapter useful in moving your fundraising campaign for us. Next week, join us to read “Chapter 12: Anatomy of an Allocation Process.”

Enjoyed the preview? Buy now from Amazon.com or Barnes & Noble

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RESI Boston Panel Announcement: Early Stage Therapeutics Investors

By Lucy Parkinson, Director of Research, LSN

Boston is often called the center of the global biotechnology industry, and it’s therefore no surprise that investors are flocking to RESI Boston to meet with early stage drug development entrepreneurs. LSN has gathered a panel of 5 top investors in therapeutics to share their tips and insights on the assessment of novel therapeutic technologies.

These five panelists will be sharing their expertise with RESI’s audience:

The panel will cover the challenges of raising capital for early stage drug development.  It’s a high-risk, high-reward investment sector, and these five investors have a wealth of experience in searching for the strongest early stage opportunities.  Representing diverse groups, from foundations to VC to pharma, these investors will explain how you can position your company to work with them.  If you’re interested in catching this panel live, you can sign up for RESI Boston now.

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Elevating an Ecosystem – Incubators, Accelerators, and New Models Panel at RESI on MaRS

By Caitlin Kramer, Research Analyst, LSN

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Incubators, accelerators, and other organizations are increasingly emerging as conduits for early stage life science companies to plug in to pre-existing networks, infrastructure, and capital.  Entrepreneurs may find themselves faced with choosing whether to participate in such programs, and weigh and evaluate the benefits a given program may offer in helping them achieve their goals. At RESI on MaRS, five panelists from different groups in this sector discussed the topic from their own unique positions, each presenting the specialties and area of focus of their organization.

Moderated by Rebecca Yu, Head of JLABS @ Toronto, Johnson & Johnson Innovation (JLABS), panelists include

Each model has a unique value proposition which lies in its approach to network-building

Across the board, incubators, accelerators, and other models act as hubs for connecting startups to a wide range of entities; but which entities? Christopher Kim (KSL) shared how he brings in experienced Entrepreneurs in Residence to work with management teams on their project, as well as interfacing with potential customers through his contacts in Big Pharma. Linda Maxwell elaborated on the outbound offering of Biomedical Zone, where the “focus is getting clinicians involved with the technology, to not just look at the clinical outcomes, but the business case validation.” BioMedical Zone helps companies execute pilot programs to deploy products in their partner hospitals such as St. Michael’s, where traction is gained with the people who will ultimately champion the products. Autodesk’s approach, described by Gordon Kurtenbach, is “positioning ourselves in a community, opening up our doors, and establishing a social relationship to find out what is interesting to all of us.” Dianne Carmichael said that MaRS Discovery District adds value through providing expertise and preparation to companies, as well as exposure to investors and partners – so that when entrepreneurs finally pitch to a good fit investor, they are prepared and polished. “Gone are the days when fundraising CEO’s are thrown in front of organizations that have no intention of partnering or investing in them”, she said.

Elevating the early stage ecosystem

“With incubators and accelerators, there’s somewhere in the neighborhood of 7500 of them in North America”, said Carmichael.  She described how with this, there are many resources to “help companies that are starting…but I would argue that many of them don’t last.” At MaRS, a major focus is elevating the reputation of the entire early stage model ecosystem by carrying out due diligence on potential portfolio companies, and ensuring that the technology and management teams are well developed and prepared for talks with investors. Maxwell, herself an advisor to MaRS, described “working towards a new investment model, where investors are other hospitals, where we develop technology or pilot technology that people are mutually interested in.” This would result in “broadening the landscape for piloting and demonstrating clinical and business case validation.”

International collaboration is important at the earliest stages

For many companies, the “next stage” of success lies on penetrating international markets – particularly the US and Asian markets. Bringing in international investors is an excellent way to gain early exposure to global markets, competitors, and networks. For this reason, international collaboration is a key theme for firms like KSL and innovation hubs like MaRS. The relationship between people and hubs in the US and Canada are emphasized by Carmichael and Maxwell. “It’s easier to start a company in Canada than it is virtually anywhere else in the developed nations, but we have a real problem with scaling,” said Carmichael. Maxwell went on, “until we develop our own infrastructure for really adequate scaling of companies, early stage companies are going to go to the US” for that purpose.

Final Remarks

The early stage ecosystem is ripe with resources for entrepreneurs. There are a variety of models, some more hands-on than others. These will be the models that perform diligence, and bring in/coordinate with outside expertise and investors with a customized approach for their portfolio companies. Other models are more “open door”. Companies would not be expected to achieve milestones or need to wait for diligence, but should not expect the same level of guidance and support network that more rigid programs offer. Entrepreneurs should evaluate whether there is alignment between their goals and the specific “value proposition” of a given model.

LSN Summer Reading Series Chapter 10: “Phone Canvassing”

By Nono Hu, Director of Marketing, LSN

Once you have a global target list of investors as we outlined in last week’s chapter, you will want to begin going outbound and contacting these groups. With this week’s edition of the summer reading series, we explain what goes into an effective phone canvassing campaign.

“Chapter 10: Phone Canvassing” goes through the process of reaching out to potential investors effectively via the phone. Now the idea of contacting investors, or anyone for that matter, via a cold call may sound daunting to many fundraising entrepreneurs; however, in the highly competitive marketplace for early stage investment, entrepreneurs should use this and all professional tactics available to them in order to separate from the crowd and garner more attention from potential investors.

Click here to download/print the chapter PDF

Join us next week for Chapter 11: “Email Campaigns”

Enjoyed the preview? Buy now from Amazon.com or Barnes & Noble

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RESI Boston Panel Announcement: Medtech Strategic Firms Partnering for Innovation

By Lucy Parkinson, Director of Research, LSN

It’s well known that big pharma firms are often looking to partner early.  Many major medical device companies are also looking outward for innovation, and at RESI Boston, five experienced corporate investors will explain how they use early stage device investments to strategic effect.  This panel will cover how medical device entrepreneurs should approach a larger company for an investment or development partnership, and what kinds of investment these major players are currently focused on.

These five panelists will be sharing their expertise with RESI’s audience:

If you’re interested in hearing from these firms on their varied approaches to early stage innovation, you can register for RESI now.

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