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Going To a Conference? Follow These Four Tips for Partnering Success

17 Mar

By Jay Doherty, Business Development, LSN

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Like many players in healthcare, the Life Science Nation team travel around the world to attend partnering conferences and build dialogue with investors and fundraising CEOs. We’ve had the opportunity to see both the best and the worst in partnering, and have also heard from investors about what catches their attention in a partnering message. Last year, LSN provided a template partnering message designed to increase your response rate when reaching out to investors. Here are some additional tips for successful partnering requests:

Be brief and concise in your outreach. Investors want to see enough information to entertain a meeting, but will not spend all day reading an introductory email. Hit the points you need to and ask for a meeting.

Follow up on your requests. If you have not heard back after a few days, send another message, and follow up with a phone call if possible. Investors are flooded with emails daily and cannot catch every one. Being persistent and politely resending a request will likely get an answer, and hopefully a meeting, quicker than leaving it to chance.

Do not be deterred by a full schedule. Investor schedules will fill up for a partnering event, but that does not mean they absolutely have no time to chat. Be proactive, suggest an ad hoc meeting, or a quick introduction throughout the course of the day. You might not get every meeting you want, but getting in front of an investor for a brief moment will better your chances of securing a meeting down the road.

Make sure you set yourself up for the future. Do not forget to get an investor’s contact information at the end of the meeting. Even if you’re not a fit for their current investment preferences, they might be able to connect the dots for you elsewhere.

By sticking to these fundamentals, you can make it easier for an investor to identify you as a fit for their investment strategy. This will lead to higher response rates and more productive meetings.

RESI@TMCx Panel Announcement: Incubators, Accelerators & New Models

17 Mar

By Lucy Parkinson, Director of Research, LSN

With the explosion of activity in early stage life sciences in the last few years, many new programs have been formed to support the youngest new biotech, medtech and healthcare IT companies in developing their products and making first steps toward commercialization.

This RESI panel will highlight five programs that provide vital resources at the earliest stage, including support, work space, mentoring, business education, and investment. The panelists will talk about how they select companies, how they help entrepreneurs turn scientific ideas into commercial success stories, and what makes each of their programs unique.

Moderated by Atul Varadhachary, Managing Partner, Fannin Innovation Studio, this session will feature:

How Massachusetts Wins the War for Global Talent

10 Mar

By Bill Brah, Founder and Director, UMass VDC

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“54% of the life science companies (including MIT spinout SQZ Biotech) launched at the VDC were founded by foreign-born entrepreneurs that came to Massachusetts for graduate study and remained to launch a company. The Massachusetts Global Entrepreneur-in-Residence Program has increased their odds of getting a visa from less than 50% to 100%!”

The Venture Development Center, more commonly referred to as the “VDC” at University of Massachusetts in Boston, is an experienced community guiding startup companies from vision to launch, no strings attached. Ninety-five entrepreneurs, both from life science and technology, are currently in residence. About one-third are from UMass, while the rest are from Harvard, MIT and other universities.

It is truly a special place. Not a day goes by without learning something new from an entrepreneur. That’s because the entire VDC staff spends a lot of time listening. Listening with the goal of understanding is the key to being helpful to entrepreneurs. It’s also the precursor to discovering new opportunities to help many entrepreneurs.

Only by listening can you link together pieces of information to reveal bigger ideas to make the business ecosystem more supportive. My experience in business, university and government helps me to see connections. But it is our willingness to experiment that allows the VDC to then integrate them into something that never existed before.

Great teams are looking for an opportunity to startup

This is how the VDC came into being in 2009. (I’m Assistant Vice Provost for Research at UMass Boston, and the Founder and Director of the VDC.) We knew the city had been awash in NIH grants for decades and could see the shifting emphasis on translation (commercializing research) versus discovery. Our own university was growing in life science. Other tech transfer officers confirmed the shortage of lab space suitable for founders ready to take the tactical step from their university labs to environments where they could prove out the technology by generating the data needed to raise financing. Small, reasonable priced and well-located facilities would be a draw, despite being outside the traditional hub Kendall Square. At the end of the day scientist entrepreneurs will always choose the best value for deployment of their scarce capital.

The bargain with UMass was that I could have 18,000 square feet of hotly contested space (a former cafeteria) in the heart of the campus if our team raised the money to build startup labs and offices externally, and be financially self-sufficient. This would also serve as an example for others on campus to be more entrepreneurial. We started in 2006, and successfully raised $7.8M from five different sources to build the VDC.

We opened the VDC in 2009 at the height of the global financial crisis, when investors had taken a walk on biotech, making it challenging for new companies to get financed. However, it was still apparent that there were great teams looking for an opportunity to start. The VDC started small with only four labs and launched 13 venture backed biotech startups that eventually raised over $130M. Three months ago, one of our companies, SQZ announced a $500M deal with Roche to fight cancer with novel cell engineering technology.

Focus on global entrepreneurs

This same dedication to listening how to make the ecosystem more supportive of entrepreneurs led the VDC to jump into Massachusetts’ pioneering Global EIR Program when leaders at other universities wouldn’t.

I got a call in 2013 from Pam Goldberg of the Mass Tech Collaborative who asked if I’d join a group of heavy hitters who had been working on Mass Passport, a strategy to help startup founders get visas so they could stay after they graduate and launch their business.

Why did I eagerly volunteer to pilot and now lead the program? Because the VDC attracts science and engineering focused entrepreneurs, I had come in contact with many who came from abroad to study at our universities. 54% of the 13 life science companies (including SQZ) launched at the VDC were founded by foreign-born entrepreneurs who came to Massachusetts for graduate study and remained to launch a company. They all talked about their immigration woes.

I also understood that my own university was globalizing. Many of our students are first generation and have modest means, unable to afford to study abroad. Surrounding them with global entrepreneurs would give them a great experience, and maybe even a great job.

For their sake, I understood how vital it is for Massachusetts to win the global war for talent. A conversation years earlier, in 2010, with Iker Marcaide helped me to connect the dots. Iker graduated the previous year from the Massachusetts Institute of Technology – Sloan School of Management. He told me about his startup, peerTransfer, which helps universities streamline the processing of international tuition payments. But would UMass be willing to try the service out for itself and would any students be interested in joining the peerTransfer team?

Marcaide, a Spanish national, started the firm after being shocked by the cost of wiring fee payments from abroad. peerTransfer is solving a problem most don’t realize is a problem: it’s difficult and expensive for international college students to transfer money to pay their tuition. 55,447 currently attend a Massachusetts university, 8.2% more than in 2014.

Now called Flywire, the Boston-based company has raised $43M in venture capital, and last year doubled its revenues and headcount to 98.

Iker ended up hiring Catherine Cam, a Newton North High School grad and UMass Boston economics major. Cam worked at peerTransfer for 13 months as a Sales Operations & Marketing Intern while she completed her studies. She’s now an applications developer at Granite Communications.

Iker opened my eyes to the thousands of business, science, and engineering graduate students who attend a university in Massachusetts on an F-1 visa and desire to remain to grow a company. I also learned that Iker is a lucky one. The odds of international students like him obtaining an H-1B work visa in the national lottery after graduating are less than 50%. It is so challenging for startup founders to simply qualify that many don’t even try.

Reversing the exodus of Massachusetts most entrepreneurial grads

After the idea of an entrepreneur startup visa died in Washington, D.C., the Mass Passport group was formed. Massachusetts wanted to take matters into its own hands and increase the odds for grads like Iker. But they needed a university to step forward to use its cap-exempt status (allowing an entrepreneur to bypass the national H-1B lottery and get a cap-exempt visa) to make the program work. UMass was the only university willing to lead.

The Senate and House staff who worked on the bill to provide money for what is now known as the known as the Massachusetts Global Entrepreneur-in-Residence Program (GEIR) had no problem with engaging in regulatory competition with the feds, but wanted answers to convince their members why this was good for the state. Shouldn’t we be helping our own native born entrepreneurs? I drew on plenty of stories foreign-born entrepreneurs had told me, and pointed to what job creating machines their startups were.

Greg Bialecki, Massachusetts Secretary of Housing and Economic Development, understood the need for more evidence, as a result the VDC received funds from the Mass Tech Collaborative to pilot the program with two entrepreneurs.

Jeff Bussgang, a Flybridge partner, and the driver behind the GEIR idea, told me, we’d better find a way to add more entrepreneurs. Two entrepreneurs prove little. Even though they were his students from Harvard Business School, statistics say their companies might not survive, even though in failure, they’d become better entrepreneurs. This is a hits based business, and depends on lots and lots of trips to the plate.

So, through scrappy experimentation, Jeff and I figured out how to add more entrepreneurs without any more state money. Good thing, because the state had a budget deficit, and couldn’t make good on its $3M promise.

Last week, GEIR reached a milestone – its 10th visa. What this means is that GEIR has increased the odds of entrepreneurs graduating from our universities getting a work visa from less than 50% to 100%!

It took all of 2015 to get these 10 visas. I’ve probably spent 25% of my time on it. Each visa involves a laborious, 22 step, three-month process involving as many as nine administrators at UMass. The way the university has rallied around GEIR is impressive.

The total venture capital raised by the 10 entrepreneurs’ nine companies is $49.9M. The companies have a headcount of 137 employees. We are in process of doubling the number of entrepreneurs in 2016, with 13 already accepted. The next challenge is how to support hundreds more who want to remain after they graduate and grow a business. I think it is time other universities follow our lead.

Making the ecosystem stronger is everyone’s mission

GEIR has been transformative for the entrepreneurs and hopefully Massachusetts. We’ve written the playbook how to reverse the exodus of a group of our most important grads. Founders in California have even moved back to participate in the program!

I am proud that UMass has stepped up to the plate to make our ecosystem stronger. After all, that’s its mission as a public university.

But it should be everyone’s mission. So, let’s stop boasting about Massachusetts being the most innovative state, and instead listen more carefully how to make it the best in the world for global entrepreneurs.

RESI@TMCx Panel Announcement: Early Stage Therapeutic Investors

10 Mar

By Lucy Parkinson, Director of Research, LSN

Early stage therapeutics companies have a long road ahead to reach the marketplace, and will require significant investment along their way. The level of risk involved at this stage deters some investors, and much has been written about the pull-back of many venture capital firms from this phase of investment. At RESI, a panel of 5 investors who are highly experienced in investing in early stage therapeutic development will discuss how they pick winning scientfic teams and support their portfolio companies through the challenges of the development process.

Moderated by Lisa Rhoads, Managing Director, Easton Capital, the panel will feature:

This panel will give fundraising entrepreneurs a firsthand look at the strategies used by early stage therapeutic investors to assess companies at the earliest, riskiest stage of development, and will help the audience to position their companies as an attractive investment opportunity.

By registering for RESI@TMCx, you’ll be able to listen to the early stage therapeutic panel live in person, and also experience numerous opportunities to expand your network in the life sciences and to learn more about the fundraising process.

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RESI@TMCx Panel Announcement: Venture Philanthropy Investors

10 Mar

By Christine A. Wu, Research Analyst, LSN

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Venture philanthropy organizations provide more than just financing. Often times, these investors can provide a network of experts, patients, and resources in their niche space. Here in Next Phase, LSN has previously covered trends in venture philanthropy investment and advice in how to approach venture philanthropy investors.

LSN is pleased to announce a panel of five investors in the venture philanthropy space for RESI@TMCx on April 11th. Moderated by Jit Patel, VP of Research and Business Development of Juvenile Diabetes Research Foundation (JDRF), the panel will be joined by:

Panelists will address their specific investment criteria and unique missions; their investment decision-making process; important trends in the space; and the best approach to reach and heighten their interest.

Interested in this panel? It’s not too late to register for RESI@TMCx Houston and see this panel live. View the full RESI@TMCx agenda here. You can also view a video recap of our RESI San Francisco Venture Philanthropy session.

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Nature BioEntrepreneur Features LSN: Aligning Needs

3 Mar

By Dennis Ford, Founder & CEO, LSN

Dr. William Kohlbrenner, CSO, LSN

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Nature Magazine has published an article written by Dennis Ford (CEO) and Bill Kohlbrenner (CSO) that draws upon LSN’s expertise to provide practical guidance on capital raising for early stage life science companies.

If you are an aspiring entrepreneur spinning out a new biomedical technology or launching a biotech startup, one of your first tasks is to understand the funding process and how to tackle it. Five years ago, the accepted investment path was to write a proposal for Small Business Innovation Research (SBIR) grants, hit up a list of friends and family and canvass the local regional angel groups for ‘seed’ funding. After this first wave of funding, the next money was expected to come from venture capital (VC) entities or through collaborations with partnering companies.

What you need to know is that the world has changed, and the investor landscape has morphed. 

Read the full article at Nature.com

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At RESI@TMCx, Make Your Fundraising Budget Count

3 Mar

By Nono Hu, Director of Marketing, LSN

What does it cost to raise capital? In LSN’s experience, one signal that consistently distinguishes a company that is committed to raising capital is that the company has a realistic plan and budget for their fundraising campaign. And when a company has a budget, it’s vital to ensure that they’re getting the most return on investment (ROI) possible from their campaign expenses.

That’s where the Redefining Early Stage Investments (RESI) Conference fits in. As a one-day event with a 1:1 ratio of investors to startup companies, RESI inundates attendees with opportunities to connect. Companies can book up to 16 face-to-face investor meetings in advance of the event; by providing so many opportunities to meet investors in one day, RESI is a high-value event for fundraising CEOs.

RESI Provides a Higher ROI for Cost Conscious CEOs

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